Search results for "PAP"

Using eye-tracking to assess sourcing during multiple document reading: A critical analysis

2018

During the last 15 years, there have been some efforts to extend the use of eye - tracking to researching reading in complex contexts, such as the reading of multiple documents. The research community involved in this extension has been interested in higher - order comprehensio n processes occurring in complex reading contexts, such as sourcing, defined as the processes of attending to, representing, evaluating, and using available or accessible information about the sources of textual content. In this article, we argue that exte nding eye - tracking research to investigate more complex reading contexts has been made without critically reflecting on its validity in those contexts . Specific…

Conceptual Framework: Dibattito e proposte

2014

Staging Life — Interpretation of Life in Kierkegaard’s

2000

“Whether custom and social life in England is of the stuff of primieval rock or whether it consists in seams and glacial debris will become more and more apparent in the course of a few years. At times, the wanderer is overcome by a sensation comparable to that felt when climbing Rosstrappe [an elevation near Magdeburg in present-day Saxony-Anhalt], where the eye ascends over millions of seemingly loose chunks of slate”.1 These lines, published on the 21st of May, 1870 in the German newspaper Neue Preussische Zeitung by the observer Theodore Fontane, might seem, at first sight, to not be a matter of special interest to readers a century apart (unless we are interested in the literary styles…

A conformationally adaptive macrocycle : conformational complexity and host–guest chemistry of zorb[4]arene

2018

Large amplitude conformational change is one of the features of biomolecular recognition and is also the basis for allosteric effects and signal transduction in functional biological systems. However, synthetic receptors with controllable conformational changes are rare. In this article, we present a thorough study on the host–guest chemistry of a conformationally adaptive macrocycle, namely per-O-ethoxyzorb[4]arene (ZB4). Similar to per-O-ethoxyoxatub[4]arene, ZB4 is capable of accommodating a wide range of organic cations. However, ZB4 does not show large amplitude conformational responses to the electronic substituents on the guests. Instead of a linear free-energy relationship, ZB4 foll…

Further Evidence that Papillomavirus Capsids Exist inTwo DistinctConformations

2003

ABSTRACT Cell surface heparan sulfate proteoglycans (HSPGs) serve as primary attachment receptors for human papillomaviruses (HPVs). To demonstrate that a biologically functional HPV-receptor interaction is restricted to a specific subset of HSPGs, we first explored the role of HSPG glucosaminoglycan side chain modifications. We demonstrate that HSPG O sulfation is essential for HPV binding and infection, whereas de-N-sulfated heparin interfered with VLP binding but not with HPV pseudoinfection. This points to differences in VLP-HSPG and pseudovirion-HSPG interactions. Interestingly, internalization kinetics of VLPs and pseudovirions, as measured by fluorescence-activated cell sorting analy…

Fragmento del discurso, hecho por ... Benedicto XIII del Orden de Predicadores, en ocasion, que en Visita Secreta admitiò à los Padres de la Minerv…

1724

Caplletra ornada Reclams

Fragmento del discurso, hecho por ... Benedicto XIII del Orden de Predicadores, en ocasion, que en Visita Secreta admitiò à los Padres de la Minerva …

Precedeix al tít.: [creu de Malta Caplletra ornada, filets Reclams

Reactivity of Nickel(II) Porphyrins in oCVD Processes—Polymerisation, Intramolecular Cyclisation and Chlorination

2019

Abstract Oxidative chemical vapour deposition of (5,15‐diphenylporphyrinato)nickel(II) (NiDPP) with iron(III) chloride as oxidant yielded a conjugated poly(metalloporphyrin) as a highly coloured thin film, which is potentially useful for optoelectronic applications. This study clarified the reactive sites of the porphyrin monomer NiDPP by HRMS, UV/Vis/NIR spectroscopy, cyclic voltammetry and EPR spectroscopy in combination with quantum chemical calculations. Unsubstituted meso positions are essential for successful polymerisation, as demonstrated by varying the porphyrin meso substituent pattern from di‐ to tri‐ and tetraphenyl substitution. DFT calculations support the proposed radical oxi…

Nutraceuticals and functional foods for the control of plasma cholesterol levels. An intersociety position paper

2018

Current evidence shows that cholesterol management either reduces the likelihood of cardiovascular disease (CVD) or slows down its progression. Hence, it is important that all health professionals make appropriate use of all the available intervention strategies to control risk factors: from dietary improvement and positive lifestyle changes to the use of functional foods, food supplements, and drugs. This review examines the effect of the most frequently occurring cholesterol-lowering substances in functional foods or in supplements across Europe, namely plant sterols and stanols, monacolin K found in red yeast rice, berberine and beta-glucans. We conclude that currently available suppleme…

Medical Student Ultrasound Education, a WFUMB Position Paper, Part II. A consensus statement of ultrasound societies.

2020

Ultrasound is becoming a fundamental first-line diagnostic tool for most medical specialties and an innovative tool to teach anatomy, physiology and pathophysiology to undergraduate and graduate students. However, availability of structured training programs during medical school is lagging behind and many physicians still acquire all their ultrasound skills during postgraduate training.There is wide variation in medical student ultrasound education worldwide. Sharing successful educational strategies from early adopter medical schools and learning from leading education programs should advance the integration of ultrasound into the university medical school curricula. In this overview, we …