Search results for "PAPER"
showing 10 items of 2166 documents
Assessing the case of Dengue in Argentina 2009: discrimination and fear
2010
After almost a decade, the re-appearance of Dengue in Argentina caused panic and fears. Unlike Bolivia, Brazil and Paraguay where policies of preventions have been followed, the future of dengue is uncertain for Argentina; this paper does not have any political affiliation but emphasizes the role that mass media play in the coverage of epidemics. The question as to whether a newspaper or mass media corporation should maintain a minimum of objectivity is too complex to be resolved in this short article. However, we have so far set forth a model which will help other researchers to interpret topics of this nature in the future. In moments of disorder, uncertainty or disaster, societies experi…
Evaluation of a novel monoclonal antibody against tumor-associated MUC1 for diagnosis and prognosis of breast cancer
2019
There is still a great unmet medical need concerning diagnosis and treatment of breast cancer which could be addressed by utilizing specific molecular targets. Tumor-associated MUC1 is expressed on over 90 % of all breast cancer entities and differs strongly from its physiological form on epithelial cells, therefore presenting a unique target for breast cancer diagnosis and antibody-mediated immune therapy. Utilizing an anti-tumor vaccine based on a synthetically prepared glycopeptide, we generated a monoclonal antibody (mAb) GGSK-1/30, selectively recognizing human tumor-associated MUC1. This antibody targets exclusively tumor-associated MUC1 in the absence of any binding to MUC1 on health…
Estimating Heart Rate, Energy Expenditure, and Physical Performance With a Wrist Photoplethysmographic Device During Running
2017
BackgroundWearable sensors enable long-term monitoring of health and wellbeing indicators. An objective evaluation of sensors’ accuracy is important, especially for their use in health care. ObjectiveThe aim of this study was to use a wrist-worn optical heart rate (OHR) device to estimate heart rate (HR), energy expenditure (EE), and maximal oxygen intake capacity (VO2Max) during running and to evaluate the accuracy of the estimated parameters (HR, EE, and VO2Max) against golden reference methods. MethodsA total of 24 healthy volunteers, of whom 11 were female, with a mean age of 36.2 years (SD 8.2 years) participated in a submaximal self-paced outdoor running test and maximal voluntary exe…
Self-care of heart failure patients: practical management recommendations from the Heart Failure Association of the European Society of Cardiology
2020
Self-care is essential in the long-term management of chronic heart failure. Heart failure guidelines stress the importance of patient education on treatment adherence, lifestyle changes, symptom monitoring and adequate response to possible deterioration. Self-care is related to medical and person-centred outcomes in patients with heart failure such as better quality of life as well as lower mortality and readmission rates. Although guidelines give general direction for self-care advice, health care professionals working with patients with heart failure need more specific recommendations. The aim of the management recommendations in this paper is to provide practical advice for health profe…
Surgical research and clinical routine in the new century.
2002
The German Research Foundation (DFG) has recentlydenounced the poor state of clinical research in Germany[2]. It is therefore worthwhile to contemplate the currentstate of surgical research with special focus on the futurepossibilities to combine research and clinical routine inuniversity hospitals.Current StateReading the daily newspaper one may get the impres-sion that German universities and clinical research in par-ticular are in a deep crisis, and that German professors areto be blamed for it. In medicine, additional insufficienciesof the system are obvious, with corruption cases broughtup against clinicians and conflicts of interest due to thefact that clinical professors in addition …
Mechanical rotational thrombectomy with Rotarex system augmented with drug-eluting balloon angioplasty vs. stenting for the treatment of acute thromb…
2018
Introduction Mechanical thrombectomy is an alternative to local thrombolysis for the treatment of severe ischaemia in the femoropopliteal segment, but stent implantation is usually required after this procedure. The use of drug-eluting balloons (DEBs) may overcome long-term problems associated with stents, but it remains unclear how often such a treatment is technically feasible and efficient. Aim This post hoc single-centre study was aimed at assessment of the feasibility, safety and efficacy of mechanical thrombectomy followed by application of DEBs. Material and methods Fifty-one patients, aged 69.1 ±11.6 years, were managed for acute thrombotic or chronic critical ischaemia in the femor…
Stem cells and new intervention measures as emerging therapy in cardiac surgery
2020
Cardiovascular disease (CVD) presents a great burden for elderly patients, their caregivers, and health systems. Structural and functional alterations of vessels accumulate throughout life, culminating in increased risk of developing CVD. Several inflammatory pathway are involved in vascular ageing. The growing elderly population worldwide highlights the need to understand how aging promotes CVD in order to develop new strategies to confront this challenge. In this review we analyzed the role of stem cells and new intervention measures as emerging drugs for vascular aging.Choroby układu krążenia (CVD) są ogromnym obciążeniem dla osób w podeszłym wieku i ich opiekunów, a także systemów opiek…
Anthropometric and physical characteristics allow differentiation of young female volleyball players according to playing position and level of exper…
2017
The aim of our study was to determine the differences in some anthropometric and physical performance variables of young Croatian female volleyball players (aged 13 to 15) in relation to playing position (i.e., independent variable) and performance level within each position (i.e., independent variable). Players were categorized according to playing position (i.e., role) as middle blockers (n=28), opposite hitters (n=41), passer-hitters (n=54), setters (n=30), and liberos (n=28). Within each position, players were divided into a more successful group and a less successful group according to team ranking in the latest regional championship and player quality within the team. Height and body …
Can supplementation with vitamin C and E alter physiological adaptations to strength training?
2014
Published version of an article from the journal: BMC Sports Science, Medicine and Rehabilitation. Also available from the publisher: http://dx.doi.org/10.1186/2052-1847-6-28 Background: Antioxidant supplementation has recently been demonstrated to be a double-edged sword, because small to moderate doses of exogenous antioxidants are essential or beneficial, while high doses may have adverse effects. The adverse effects can be manifested in attenuated effects of exercise and training, as the antioxidants may shut down some redox-sensitive signaling in the exercised muscle fibers. However, conditions such as age may potentially modulate the need for antioxidant intake. Therefore, this paper …
Position Paper on Young Vascular Surgeons Training of the Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS): State of the Art a…
2021
ABSTRACT The Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS) was founded in 2018, with the aim to promote cooperation among vascular professionals within Mediterranean countries. Due to its prominent social and economic impact on national health systems, diabetic peripheral artery was selected as the very first topic to be investigated by the federation. In this second paper, different experiences from delegates of participating countries were shared to define common strategies to harmonize, standardize, and optimize education and training in the Vascular Surgery specialty.