Search results for "PASS"
showing 10 items of 1629 documents
Design of Implanted RFID Tags for Passive Sensing of Human Body: The STENTag
2012
Numerical processing of passive UHF-RFID tags' response may provide physical insight about the hosting object or about the nearby environment. This idea is here extended to implanted antennas with the purpose to sense the evolution of some human physiological and pathological process involving a local change of effective permittivity inside the body. The goal is to understand how master the design of this class of devices taking into account both communication and sensing capabilities. An ad hoc design methodology is here presented and discussed by means of a realistic medical case concerning the modification of an endo-vascular device to achieve a STENTag able to sense the state of the ves…
Retention-activity relationship studies of benzodiazepines by micellar liquid chromatography
1999
Solute partitioning into lipid bilayers of biological membranes is the basis for drug and metabolite uptake, passive transport across membranes and bioaccumulation. In order to emulate in vitro the partitioning process in the biomembranes, different approaches have been proposed. The use of micellar solutions as mobile phases in reversed-phase liquid chromatography (micellar liquid chromatography, MLC) has proven to be valid in the prediction of the biological activities of local anesthetics, catecholamines and barbiturates. In this paper we focus our attention on benzodiazepines. The retention of benzodiazepines using different concentrations of Brij35 as micellar mobile phase in modified …
Development of predictive retention-activity relationship models of antipsychotic drugs by micellar liquid chromatography
1999
The predictive and interpretative capability of quantitative chromatographic retention-biological activity models is supported by the fact that in adequate experimental conditions the solute partitioning into the chromatographic system can emulate the solute partitioning into lipid bilayers of biological membranes, which is the basis of drug and metabolite uptake, passive transport across membranes and bioaocumulation. The use of micellar solutions of Brij35 as mobile phases in reversed liquid chromatography has proven to be valid in predicting some biological activities of different kinds of drugs. In this paper, the correlations between the logarithm of capacity factors and pharmacokineti…
Medidas de Tromboprofilaxis en Artroplastia Total de Rodilla. Práctica habitual en la Comunidad Valenciana y revisión bibliográfica.
2020
espanolAntecedentes: El tromboembolismo es una complicacion de la cirugia de artroplastia total de rodilla. Para su prevencion disponemos de multiples medidas fisicas y farmacologicas.Objetivo:Conocer quemedidas de prevencion tromboembolica son las empleadas por los cirujanos ortopedicos en cirugia protesica de rodilla primaria en diferentes centros hospitalarios de nuestra region.Metodo: Estudio transversal descriptivo observacional basado en encuesta dirigida a especialistas COT de 9 hospitales publicos de la Comunidad Valenciana y busqueda bibliografica.Resultados: Se obtuvieron 64 encuestas. Todos los cirujanos eligen HBPM durante un mes como medida de tromboprofilaxis, descartando anti…
Development of predictive retention-activity models of butyrophenones by biopartitioning micellar chromatography
2001
The predictive and interpretative capability of quantitative chromatographic retention-biological activity models is supported by the fact that in adequate experimental conditions the solute partitioning into the chromatographic system can emulate the solute partitioning into lipid bilayers of biological membranes, which is the basis of drug and metabolite uptake, passive transport across membranes and bioaccumulation. The use of retention data obtained in biopartitioning micellar chromatography (BMC) has been demonstrated to be helpful in describing the biological behaviour of different kinds of drugs. In this chromatographic system, polioxyethylene 23 lauryl ether Brij35 micellar mobile p…
Development of Predictive Retention-Activity Relationship Models of Barbiturates by Micellar Liquid Chromatography
2000
The need to get a tool for biological parameters estimation of new compounds for clinical applications, supports the postulation of predictive models as an alternative to conventional classical assays being no necessary the use of experimentation in animals. Our main aim in this work is to determine correlations between the logarithm of capacity factors and preclinical pharmacology and therapeutic efficacy parameters of barbiturates. The predictive and interpretative capability of quantitative chromatographic retention-biological activity models is supported by the fact that in adequate experimental conditions the solute partitioning into chromatographic system can emulate the solute partit…
Phenomenology of the Poetical
2004
These lines from “The Doctrine of the Point of View” by Jose Ortega y Gasset, the fragment devoted to the ever-existing antinomy between life and culture and their interpretations from the rationalistic and relativistic view points, are the perfect opening for the present paper as they capture the sense and the mood of the philosophical endeavor taken upon by Anna-Teresa Tymienicka in Poetica nova and Book 3 of Logos and Life: The Passions of the Soul and the Elements into Onto-Poiesis of Culture. In short it could be summarized as the inquiry into phenomenology of the poetical with a special emphasis on literature as the prima facie human creative activity to be approached by the means of …
Social phenotype extended to communities: expanded multilevel social selection analysis reveals fitness consequences of interspecific interactions.
2014
In social species, fitness consequences are associated with both individual and social phenotypes. Social selection analysis has quantified the contribution of conspecific social traits to individual fitness. There has been no attempt, however, to apply a social selection approach to quantify the fitness implications of heterospecific social phenotypes. Here, we propose a novel social selection based approach integrating the role of all social interactions at the community level. We extended multilevel selection analysis by including a term accounting for the group phenotype of heterospecifics. We analyzed nest activity as a model social trait common to two species, the lesser kestrel (Falc…
Eurípides: de la moral pensada a la moral vivida
2011
ResumenLa tragedia griega sigue siendo un gran referente de reflexión filosófica. En este artículo nos centraremos en la figura de Eurípides, concretamente en el tema de los juicios morales que trasmiten sus obras trágicas. La cuestión es que si en Esquilo la razón triunfaba sobre el dilema trágico, en Eurípides no se ve claro ese triunfo si viene impuesto desde fuera y no ha arraigado en el corazón de los ciudadanos. La razón tiene muchas dificultades para ejercer su control sobre la acción y orientarla hacia el bien común. Eurípides planteará que es la persona, su conciencia interior, la que debe de estar convencida de que algo le obligue moralmente. El paso de una moral pensada a una mor…
Can the Excluded Criticize? On the (Im)possibilities of Formulating and Understanding Critique
2021
If critique does not want to be more than just a ‘passion of the head’ it has to engage in dialogue with the worst-off in society. However, there are several mechanisms that hinder the excluded fro...