Search results for "PATHOLOGY"

Time course of asymmetric dimethylarginine (ADMA) and oxidative stress in fructose-hypertensive rats: A model related to metabolic syndrome

2011

Asymmetric dimethylarginine (ADMA) is an endogenous modulator of endothelial function and oxidative stress, and increased levels of this molecule have been reported in some metabolic disorders and cardiovascular diseases. The aim of this work was to analyze the time course of dimethylarginine compounds and oxidative stress levels and the relationship between these and cardiovascular function in fructose-hypertensive rats.90 male Sprague-Dawley rats were randomized into 2 groups, fed for 3 months with standard (C) chow supplemented or not with fructose (F, 60%). After sacrifice at different weeks (W), the aorta and plasma were harvested to assess the vascular and biochemical parameters. Our …

Identification of factors involved in dimorphism and pathogenicity of Zymoseptoria tritici

2017

A forward genetics approach was applied in order to investigate the molecular basis of morphological transition in the wheat pathogenic fungus Zymoseptoria tritici. Z. tritici is a dimorphic plant pathogen displaying environmentally regulated morphogenetic transition between yeast-like and hyphal growth. Considering the infection mode of Z. tritici, the switching to hyphal growth is essential for pathogenicity allowing the fungus the host invasion through natural openings like stomata. We exploited a previously developed Agrobacterium tumefaciens-mediated transformation (ATMT) to generate a mutant library by insertional mutagenesis including more than 10,000 random mutants. To identify gene…

Longitudinal Analysis of Serum Autoantibody-Reactivities in Patients with Primary Open Angle Glaucoma and Optic Disc Hemorrhage.

2015

Background The aim of our current investigation was to analyze the autoantibody-reactivities of primary open angle glaucoma patients with optic disc hemorrhage as possibly correlated to disease progression by means of a protein microarray approach. Methods Sera of patients with primary open angle glaucoma and optic disc hemorrhage (n = 16) were collected directly after study inclusion (0 weeks) and after 2 weeks, 4 weeks and 12 weeks. As a control group patients with primary open angle glaucoma (n = 18) were used (0 weeks and 12 weeks). Microarrays were incubated and occurring antibody-antigen-reactions were visualized with fluorescence labeled anti-human-IgG secondary antibodies. To detect…

Syndrome de tracation vitréomaculaire

2017

Le traitement médical de l'oedème maculaire

2019

Data from: Correlational selection on pro- and anti-inflammatory effectors

2012

Parasites impose a permanent threat for hosts. As a consequence, immune defenses are important for host fitness. However, the immune response can also produce self-damage and impair host fitness if not properly regulated. Effectors that up- and down-regulate the immune response should, therefore, evolve in concert, and be under the action of correlational selection. To address this issue, we assessed the shape of the selection operating on pro- and anti-inflammatory effectors following an inflammatory challenge in laboratory mice. We found that selection acts on the combination of these two traits as individuals that produced large amount of pro-inflammatory cytokines could achieve relative…

Oral Pathology and Oral Medicine

2015

This is a multidisciplinary publication for all fields of oral medicine. This book builds a bridge between basic and clinical sciences, promoting the exchange of information and the advancement of oral medicine for the benefit of patients and clinicians. It offers comprehensive coverage of new techniques, important developments, and innovative ideas in all fields of clinical dentistry.

Psychopathology exercise book 2nd semester

2019

El document ha sigut revisat pel Servei de Política Lingüística de la Universitat de València El siguiente folleto tiene un objetivo modesto pero necesario en el contexto universitario de la enseñanza de psicopatología, una disciplina básica para cualquier profesional futuro en psicología: proporcionar ejemplos reales de diversas formas de presentación de psicopatologías, para que los estudiantes puedan familiarizarse con ellos y relacionarlos con ellos. Los conocimientos adquiridos en la enseñanza teórica. The following booklet has a modest but necessary objective in the university context of teaching psychopathology, a basic discipline for any future professional in psychology: to provide…

Apikālā periodontīta sastopamības biežums un endodontikās ārstēšanas kvalitāte pieaugušo izvēlētā populācijā Latvijā

2022

Apikālais periodontīts (AP) ir izplatīta hroniska iekaisuma slimība, kas izpaužas kā dinamiska organisma aizsargreakcija pret mikrobu infekciju zobu sakņu kanālu sistēmā. Pētījumi liecina, ka AP ir plaši izplatīts pieaugušajiem - vismaz viens zobs ar AP ir 27 - 80% pieaugušo (Kirkevang & Vaeth, 2019). AP ir tieša saistība ar sakņu kanālu ārstēšanas kvalitāti – nekvalitatīva ārstēšana tiek saistīta ar palielinātu AP izplatību (Chala et al., 2011; Meirinhos et al., 2020). Darba mērķis bija izpētīt apikālā periodontīta izplatību un endodontiskās ārstēšanas biežumu un kvalitāti izvēlētā Latvijas pieaugušo populācijā.