Search results for "PC(O)"
showing 10 items of 172 documents
A novel pro-apoptotic role of zinc octacarboxyphthalocyanine in melanoma me45 cancer cell's photodynamic therapy (PDT)
2018
Abstract Zn-based phthalocyanine acts as drug or photosensitizer in photodynamic therapy (PDT) for the treatment of cancer cells. The activated zinc octacarboxyphthalocyanine (ZnPcOC) reacts with oxygen, to generate reactive oxygen species for the damage of melanoma cancer cells, Me45. This in vitro study aimed at investigating the cytotoxic effects of different concentrations of ZnPcOC activated with a diode laser (λ = 685 nm) on Me45, and normal human fibroblast cells, NHDF. To perform this study 104 cells/ml were seeded in 96-well plates and allowed to attach overnight, after which cells were treated with different concentrations of ZnPcOC (10, 20 and 30 μM). After 4 h, cells were irradi…
Initial Biological Assessment of Upconversion Nanohybrids
2021
Nanoparticles for medical use should be non-cytotoxic and free of bacterial contamination. Upconversion nanoparticles (UCNPs) coated with cucurbit[7]uril (CB[7]) made by combining UCNPs free of oleic acid, here termed bare UCNPs (UCn), and CB[7], i.e., UC@CB[7] nanohybrids, could be used as photoactive inorganic-organic hybrid scaffolds for biological applications. UCNPs, in general, are not considered to be highly toxic materials, but the release of fluorides and lanthanides upon their dissolution may cause cytotoxicity. To identify potential adverse effects of the nanoparticles, dehydrogenase activity of endothelial cells, exposed to various concentrations of the UCNPs, was determined. Da…
Dynamic Characterization of Upconversion in Highly Er-Doped Silica Photonic Crystal Fibers
2012
Measurements of time evolution of amplified spontaneous emission for square-wave modulated pump were made on a highly erbium-doped silica photonic crystal fiber and fitted to theoretical results calculated using different formalisms to describe the ${\rm Er}^{3+}$ -ion migration-assisted co-operative upconversion mechanism in the population densities rate equations. The determined characterization parameters are the constant homogeneous upconversion coefficient, 3.0 $\times 10^{-24}~{\rm m}^{3}/{\rm s}$ , the critical radii for upconversion and migration, 10.5 and 14A, respectively, and the rate of clustered ions, 14%. These parameters are analysed and compared to those obtained with contin…
Lifecycle of Polycystic Ovary Syndrome (PCOS): From In Utero to Menopause
2013
Context: Polycystic ovary syndrome (PCOS) is diagnosed during the reproductive years when women present with 2 of 3 of the following criteria: 1) irregular menstrual cycles or anovulation, 2) hyperandrogenism, and 3) PCO morphology. However, there is evidence that PCOS can be identified from early infancy to puberty based on predisposing environmental influences. There is also increasing information about the PCOS phenotype after menopause. The goal of this review is to summarize current knowledge about the appearance of PCOS at different life stages and the influence of reproductive maturation and senescence on the PCOS phenotype. Evidence: PubMed, the bibliography from the Evidence-Based …
Ultrafast broadband fluorescnce up-conversion of N-acetyl-L-tryptophanamide (NATA)
2011
GAPPCO: An Easy to Configure Geometric Algebra Coprocessor Based on GAPP Programs
2017
Because of the high numeric complexity of Geometric Algebra, its use in engineering applications relies heavily on tools and devices for efficient implementations. In this article, we present a novel hardware design for a Geometric Algebra coprocessor, called GAPPCO, which is based on Geometric Algebra Parallelism Programs (GAPP). GAPPCO is a design for a coprocessor combining the advantages of optimizing software with a configurable hardware able to implement arbitrary Geometric Algebra algorithms. The idea is to have a fixed hardware easily and fast to be configured for different algorithms. We describe the new hardware design together with the complete tool chain for its configuration.
RUOLO DELL’EPITELIO RESPIRATORIO NELLA RISPOSTA IMMUNITARIA INNATA DEI PAZIENTI CON BPCO
2012
Consensus On Women'S Health Aspects Of Polycystic Ovary Syndrome (Pcos)
2012
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females with a high prevalence. The etiology of this heterogeneous condition remains obscure and its phenotype expression varies. Two, widely cited, previous ESHRE/ASRM-sponsored PCOS consensus workshops focused on diagnosis (published in 2004) and infertility management (published in 2008). The present third PCOS consensus paper summarizes current knowledge and identifies knowledge gaps regarding various women's health aspects of PCOS. Relevant topics addressed-all dealt with in a systematic fashion-include adolescence, hirsutism and acne, contraception, menstrual cycle abnormalities, quality of life, ethnicity, preg…