Search results for "PC"

Functional Principal Component Analysis for the explorative analysis of multisite-multivariate air pollution time series with long gaps

2013

The knowledge of the urban air quality represents the first step to face air pollution issues. For the last decades many cities can rely on a network of monitoring stations recording concentration values for the main pollutants. This paper focuses on functional principal component analysis (FPCA) to investigate multiple pollutant datasets measured over time at multiple sites within a given urban area. Our purpose is to extend what has been proposed in the literature to data that are multisite and multivariate at the same time. The approach results to be effective to highlight some relevant statistical features of the time series, giving the opportunity to identify significant pollutants and…

Cytotoxic Isomalabaricane Triterpenes from the Marine Sponge Rhabdastrella globostellata

2006

Fourteen isomalabaricane triterpenes were isolated from the marine sponge Rhabdastrella globostellata. In addition to the known compounds globostellatic acids A (1) and D (4) and stelliferin riboside (13), 11 of the compounds were new natural products, which included globostelletin (3), eight new globostellatic acid congeners, F to M (2, 5-11), and two new stelliferin ribosides (12 and 14). The isolated compounds were tested against three different cancer cell lines, L5178Y (mouse lymphoma), HeLa (human cervix carcinoma), and PC-12 (rat pheochromocytoma). The isomalabaricane derivatives were found to be selectively active toward the mouse lymphoma cell line L5178Y. The structures were deter…

A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth

2008

The planar polarity and staircase-like pattern of the hair bundle are essential to the mechanoelectrical transduction function of inner ear sensory cells. Mutations in genes encoding myosin VIIa, harmonin, cadherin 23,protocadherin 15 or sans cause Usher syndrome type I (USH1, characterized by congenital deafness, vestibular dysfunction and retinitis pigmentosa leading to blindness) in humans and hair bundle disorganization in mice. Whether the USH1 proteins are involved in common hair bundle morphogenetic processes is unknown. Here, we show that mouse models for the five USH1 genetic forms share hair bundle morphological defects. Hair bundle fragmentation and misorientation (25-52° mean ki…

Detecting topology through dynamics in interacting fermionic wires

2020

We describe a protocol to read out the topological invariant of interacting 1D chiral models, based on measuring the mean chiral displacement of time-evolving bulk excitations. We present analytical calculations and numerical Matrix Product State simulations of interacting Su-Schrieffer-Heeger (SSH) chains, demonstrating how the mean chiral displacement allows to distinguish between topological insulator, trivial insulator and symmetry-broken phases. Finally, we provide an experimental blueprint for realizing a model displaying these three phases and describe how to detect those.

Vēsture: Latvijas Universitātes Žurnāls, 2 

2016

El componente pragmático en los diccionarios: Implicaciones para la Lexicografía

2015

Dictionaries are a list of words, simple or complex, that are treated as entries (lexical items). It is usual to assert several components: the lemma or headword, named after its most neutral form, followed by an indication of the main inflections of its category: genre and number if they are names, syntactic class if they are verbs. Sometimes, indications of it are made in other aspects: etymology, pronunciation, marks of placement, area of use, register, frequency of use, etc.Among all the group, it is pointed out an area that grows daily, painstakingly, in lexicographic works: the pragmatic component. Most of the words are referential (names, verbs, adverbs), but others correspond to lan…

Impact of Destroying the Structure of Model Gels on Volatile Release

2007

International audience; The release of a strawberry aroma from different composite gels taken as models of fruit preparations and from a sucrose solution was investigated. The composition of the model systems differed with regard to the gelling agent, either pectin or carrageenan, and to the rigidity of the gel. With the use of atmospheric pressure chemical ionization−mass spectrometry, the release profiles of the aroma compounds were determined under stirring. At the same time, purge and trap measurements were performed to determine the release profiles of the aroma compounds without stirring. The comparison of the patterns obtained using these two complementary methods made it possible to…

Sympathetic neurons can produce and respond to interleukin 6

1998

Neuronal expression of cytokines is an area of active investigation in the contexts of development, disease, and normal neural function. Although cultured rat sympathetic neurons respond very weakly to exogenous interleukin 6 (IL-6), we find that addition of soluble IL-6 receptor (sIL-6R) and IL-6 enhances neuronal survival in the absence of nerve growth factor. Neutralizing monoclonal antibodies against IL-6 block these effects. Addition of IL-6 and sIL-6R also induces a subset of neuropeptide and transmitter synthetic enzyme mRNAs identical to that demonstrated for leukemia inhibitory factor, ciliary neurotrophic factor, and oncostatin M. Both of these effects are duplicated by addition o…

Fusing storage and computing for the domain of business intelligence and analytics: research opportunities

2015

With the growing importance of external and shared data, the set of requirements for Business Intelligence and Analytics (BIA) is shifting. Current solutions still come with shortcomings, esp. In multi-stakeholder environments where sensitive content is exchanged. We argue that a new level in the evolution of BIA can be unlocked by tearing down the barriers between storage and computing based on upcoming storage technologies. In particular, we propose a revitalization of ideas from object-oriented databases. We present results from a joint project that aimed at delineating design options for BIA solutions built upon this idea. The paper outlines the interplay of various architectural layers…

Quantification and viability assays of Toxoplasma gondii in commercial "Serrano" ham samples using magnetic capture real-time qPCR and bioassay techn…

2014

"Serrano" ham is a typical pork product from the Mediterranean area, highly valued for its flavour. To make Serrano ham, pork undergoes a salting and a subsequent fermentation process known as curing. Certain pigs used for meat production are an important source of Toxoplasma gondii infection in humans. We have developed a method for quantifying and assaying the viability of the T. gondii present in commercial Serrano ham samples. A magnetic capture method for the isolation of T. gondii DNA and a qRT-PCR were used to estimate the T. gondii burden in 475 commercial samples of "Serrano" ham in two presentation formats: ham pieces and sliced ham. The infectivity capacity of T. gondii in positi…