Search results for "PCO2"
showing 4 items of 24 documents
2013
Rodents are most useful models to study physiological and pathophysiological processes in early development, because they are born in a relatively immature state. However, only few techniques are available to monitor non-invasively heart frequency and respiratory rate in neonatal rodents without restraining or hindering access to the animal. Here we describe experimental procedures that allow monitoring of heart frequency by electrocardiography (ECG) and breathing rate with a piezoelectric transducer (PZT) element without hindering access to the animal. These techniques can be easily installed and are used in the present study in unrestrained awake and anesthetized neonatal C57/Bl6 mice and…
Effect of arterial oxygen tension on cerebral blood flow at different levels of arterial PCO2.
1970
Die Wirkung des arteriellen O2-Partialdruckes auf die Durchblutung des Grosshirns, Kleinhirns und Hirnstammes bei normalen und erhohten CO2-Partialdrucken im arteriellen Blut wird an der anaesthesierten Katze untersucht. Die Wirkung des PaO2 ist von der Hohe des PaCO2 abhangig.
TISSUE OXYGENATION AND TISSUE METABOLISM IN THE BRAIN CORTEX DURING PRONOUNCED ARTERIAL HYPOCAPNIA
1981
Publisher Summary This chapter describes the tissue oxygenation and tissue metabolism in the brain cortex during pronounced arterial hypocapnia. Acute arterial hypocapnia induced by hyperventilation leads to typical reactions in the circulation and the metabolism of the brain tissue. With a lowering of arterial CO2 tension, the cerebro-vascular resistance (CVR) increases resulting in a decrease of cerebral blood flow. The changes in CVR are a consequence of decreasing hydrogen ion and potassium ion concentrations in the perivascular space of the brain arterioles. The corresponding changes in the brain metabolism are characterized by elevated concentrations of lactate and pyruvate and an inc…
The accuracy of calculated base excess in blood.
2002
Most equations used for calculation of the base excess (BE, mmol/l) in human blood are based on the fundamental equation derived by Siggaard-Andersen and called the Van Slyke equation: BE = Z x [[cHCO3-(P) - C7.4 HCO3-(P)] + beta x (pH -7.4)]. In simple approximation, where Z is a constant which depends only on total hemoglobin concentration (cHb, g/dl) in blood, three equations were tested: the ones proposed by Siggaard-Andersen (SA), the National Committee for Clinical Laboratory Standards (NCCLS) or Zander (ZA). They differ only slightly in the solubility factor for carbon dioxide (alphaCO2, mmol/l x mmHg) and in the apparent pK(pK'), but more significantly in the plasma bicarbonate conc…