Search results for "PD"
showing 10 items of 1971 documents
Determinants of between-hospital variations in outcomes for patients admitted with COPD exacerbations: findings from a nationwide clinical audit (AUD…
2015
Background Previous studies have demonstrated significant variability in the processes of care and outcomes of chronic obstructive pulmonary disease (COPD) exacerbations. The AUDIPOC is a Spanish nationwide clinical audit that identified large between-hospital variations in care and clinical outcomes. Here, we test the hypothesis that these variations can be attributed to either patient characteristics, hospital characteristics and/or the so-called hospital-clustering effect, which indicates that patients with similar characteristics may experience different processes of care and outcomes depending on the hospital to which they are admitted. Methods A clinical audit of 5178 COPD patients co…
Interpolated measures with bounded density in metric spaces satisfying the curvature-dimension conditions of Sturm
2011
We construct geodesics in the Wasserstein space of probability measure along which all the measures have an upper bound on their density that is determined by the densities of the endpoints of the geodesic. Using these geodesics we show that a local Poincar\'e inequality and the measure contraction property follow from the Ricci curvature bounds defined by Sturm. We also show for a large class of convex functionals that a local Poincar\'e inequality is implied by the weak displacement convexity of the functional.
Partial discharge detection and localization along medium voltage cables
2017
In the last years different partial discharge (PD) measuring techniques have been developed because PD diagnostic is the most widely tool to evaluate the insulation condition of a power cable. Recently non-conventional methods and sensors have been used in order to reach improved results in PD measurements. The purpose of this work is to perform measurements that allow to study the variation of pulses when they travel along a MV cable and to locate the pulse source through the time arrival difference of the pulses obtained from two sensors installed separately.
1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation
2023
: Among the different hallmarks of cancer, deregulation of cellular metabolism turned out to be an essential mechanism in promoting cancer resistance and progression. The pyruvate dehydrogenase kinases (PDKs) are well known as key regulators in cells metabolic process and their activity was found to be overexpressed in different metabolic alerted types of cancer, including the high aggressive pancreatic ductal adenocarcinoma (PDAC). To date few PDK inhibitors have been reported, and the different molecules developed are characterized by structural chemical diversity. In an attempt to find novel classes of potential PDK inhibitors, the molecular hybridization approach, which combine two or m…
GOLD 2017 on the way to a phenotypic approach? Analysis from the Phenotypes of COPD in Central and Eastern Europe (POPE) Cohort.
2017
The distribution of patients based on exacerbations solely is the most profound consequence of the 2017 GOLD Report http://ow.ly/4UJa309fLbM
Study of scintillation light collection, production and propagation in a 4 tonne dual-phase LArTPC
2020
The $3 \times 1 \times 1$ m$^3$ demonstrator is a dual phase liquid argon time projection chamber that has recorded cosmic rays events in 2017 at CERN. The light signal in these detectors is crucial to provide precise timing capabilities. The performances of the photon detection system, composed of five PMTs, are discussed. The collected scintillation and electroluminescence light created by passing particles has been studied in various detector conditions. In particular, the scintillation light production and propagation processes have been analyzed and compared to simulations, improving the understanding of some liquid argon properties.
Dirichlet approximation and universal Dirichlet series
2016
We characterize the uniform limits of Dirichlet polynomials on a right half plane. In the Dirichlet setting, we find approximation results, with respect to the Euclidean distance and {to} the chordal one as well, analogous to classical results of Runge, Mergelyan and Vitushkin. We also strengthen the notion of universal Dirichlet series.
Latvijas pensiju sistēmas pilnveidošanas iespējas
2019
Maģistra darba „Latvijas pensiju sistēmas pilnveidošanas iespējas” tēma ir aktuāla, jo, kaut arī Latvijas pensiju sistēma, salīdzinot ar citām pasaules valstīm, ir augstu novērtēta un atzīta par ilgtspējīgu, ar pensiju sistēmu nav apmierināti esošie pensionāri. Latvijā pastāv augsts nabadzības risks, un vidējās pensijas apmērs ir zems. Eiropas valstīs notiek sabiedrības strauja novecošanās, kas atstāj iespaidu uz līdz šim stabilām un ilgtspējīgām pensiju sistēmām, jo strādājošajiem ir jāuztur arvien lielāks pensionāru skaits. Darba mērķis ir, pamatojoties uz pieejamo informāciju, izpētīt vecuma pensiju sistēmu Latvijā un citās valstīs un sniegt priekšlikumus tās pilnveidošanai. Darba autore…
Mobilo ierīču apdrošināšanas produkta izveide un ieviešana sistēmā TIA.
2017
TIA ir globāla apdrošināšanas sistēma, kas pārvalda apdrošināšanas procesus no sākuma līdz beigām. Sākotnēji tā tika radīta priekš viena konkrēta uzņēmuma, bet tagad to izmanto plaši pasaulē. Darba mērķis bija izveidot un ieviest mobilo ierīču apdrošināšanas produktu uz TIA kodola versijas. Mobilo ierīču apdrošināšanas produkts tika plānots izveidot kā paraugu, kuru būtu iespējams realizēt nākotnē. Uzdevums bija izveidot produktu tā, ka tam būtu jābūt iespējai izvēlēties no saraksta konkrētu ierīču modeļus vai pievienot jaunus un aprēķināt tām prēmijas, izveidot polises. Tas tika realizēts ar 1 produkta līniju, kurā būs iespējams veikt minētās darbības. Darbā ir atrodams ne vien šī produkta…
Detalizēta piekļuves kontrole datu bāzu pārvaldības sistēmās
2020
Bakalaura darba “Detalizēta piekļuves kontrole datu bāzu pārvaldību sistēmās” mērķis ir veikt pētījumu par SQL un NoSQL datu bāzēm un to atšķirībām detalizētas piekļuves kontroles nodrošināšanā. Izpētei tika izvēlētas divas datu bāzes – relāciju datu bāze Oracle un dokumentu orientēta datu bāze MongoDB Atlas. Autore veica teorētisku izpēti par datu bāzu atšķirībām, Oracle Virtual Private Database drošības risinājumu, MongoDB Atlas platformas Stitch piedāvāto drošības risinājumu , to implementēšanas iespējām un izveidoja un dokumentēja praktisku piemēru , lai apstiprinātu vai noraidītu hipotēzi – dokumentu orientētajā datu bāzē MongoDB Atlas ar platofrmu Stitch ir iespējams implementēt Oracl…