Search results for "PELE"
showing 10 items of 139 documents
North Atlantic Ice‐Rafting, Ocean and Atmospheric Circulation During the Holocene: Insights From Western Mediterranean Speleothems
2019
In this study, we present a Holocene rainfall index based on three high-resolution speleothem records from the Western Mediterranean, a region under the influence of the westerly winds belt modulated by the North Atlantic Oscillation (NAO). On centennial to millennial timescales, we show that the North Atlantic ice-rafting events were likely associated with negative NAO-like conditions during the Early Holocene and the Late Holocene. However, our data reveal that this is not clearly the case for the mid-Holocene ice-rafting events, during which we also show evidence of positive NAO-like patterns from other paleo-oceanographic and paleo-atmospheric data. Hence, contradictory mechanisms invol…
Speleothem δ13C record suggests enhanced spring/summer drought in south-eastern Spain between 9.7 and 7.8 ka – A circum-Western Mediterranean anomaly?
2019
South-eastern Spain is one of the driest regions in Europe and thus, prone to drought. Terrestrial climate records covering the late Glacial and Holocene from this area are sparse. Here, we present a flowstone record from Cueva Victoria, south-eastern Spain, which covers the late Glacial (15 ka) to the mid-Holocene (7 ka) including the Younger Dryas (YD). Between the onset of the Bølling/Allerød (B/A) and the early Holocene, flowstone δ18O values progressively decrease in accordance with sea-surface temperatures in the Alboran Sea, indicating an increase in precipitation in south-eastern Spain and a supra-regional signal of North Atlantic temperature change. At the same time, decreasing δ13…
Western Mediterranean Climate Response to Dansgaard/Oeschger Events: New Insights From Speleothem Records
2019
The climate of the western Mediterranean was characterized by a strong precipitation gradient during the Holocene driven by atmospheric circulation patterns. The scarcity of terrestrial paleoclimate archives has precluded exploring this hydroclimate pattern during Marine Isotope Stages 5 to 3. Here we present stable carbon and oxygen isotope records from three flowstones from southeast Iberia, which show that Dansgaard/Oeschger events were associated with more humid conditions. This is in agreement with other records from the Iberian Peninsula, the Mediterranean, and western Europe, which all responded in a similar way to millennial‐scale climate variability in Greenland. This general incre…
Conformational response to ligand binding in phosphomannomutase2: insights into inborn glycosylation disorder.
2014
Background: Mutations in phosphomannomutase2 cause glycosylation disorder, a disease without a cure that will largely benefit from accurate ligand-bound models. Results: We obtained two models of phospomannomutase2 bound to glucose 1,6-bisphosphate and validated them with limited proteolysis. Conclusion: Ligand binding induces a large conformational transition in PMM2. Significance: We produce and validate closed-form models of PMM2 that represent a starting point for rational drug discovery.
Climate variations of Central Asia on orbital to millennial timescales
2016
AbstractThe extent to which climate variability in Central Asia is causally linked to large-scale changes in the Asian monsoon on varying timescales remains a longstanding question. Here we present precisely dated high-resolution speleothem oxygen-carbon isotope and trace element records of Central Asia’s hydroclimate variability from Tonnel’naya cave, Uzbekistan and Kesang cave, western China. On orbital timescales, the supra-regional climate variance, inferred from our oxygen isotope records, exhibits a precessional rhythm, punctuated by millennial-scale abrupt climate events, suggesting a close coupling with the Asian monsoon. However, the local hydroclimatic variability at both cave sit…
Kalmbergin kartasto R VIIIa : List 6
1856
Speleogenesis of the Hermannshöhle cave system (Austria): Constraints from 230Th/U-dating and palaeomagnetic analysis
2015
Hermannshöhle is a show cave located near Kirchberg/Wechsel in Lower Austria. Together with three nearby and genetically connected caves, it forms the Hermannshöhlen cave system (HHS). With a length of 5 km, the HHS is the longest cave in the Lower Austroalpine unit. It is arranged as an extreme three-dimensional maze on a ground area of 200 x 200 x 82 m. Speleothems are abundant in this cave and represent the focus of this study. Low carbon isotope values indicate the presence of a soil-covered catchment above the HHS during times of speleothem deposition. 28 samples were dated by the 230Th/U-method and, in combination with palaeomagnetic data from a 5 m-high sediment profile, indicate mul…
Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages
2020
Background: During early stages, patients with neurodegenerative diseases (NDG) often present with depressive symptoms. However, because depression is a heterogeneous disorder, more precise delineation of the specific depressive symptom profiles that arise early in distinct NDG syndromes is necessary to enhance patient diagnosis and care. Methods and Findings: Five-hundred and sixty four participants self-reported their depressive symptoms using the Geriatric Depression Scale (GDS), including 111 healthy older control subjects (NC) and 453 patients diagnosed with one of six NDGs who were at the mild stage of disease (CDR® Dementia Staging Instrument ≤ 1) [186 Alzheimer's disease (AD), 76 be…
Little Egret Egretta garzetta (Linnaeus, 1766) ( Pelecaniformes Ardeidae) and Eurasian crag martin Ptyonoprogne rupestris (Scopoli, 1769) (Passerifor…
2021
For the first time, the nesting of Eurasian crag martin Ptyonoprogne rupestris (Scopoli, 1769) (Passeriformes Hirundinidae) and Little egret Egretta garzetta (Linnaeus, 1766) (Pelecaniformes Ardeidae) in the Aegadian Islands (W-Sicily, Italy) is reported. Of particular interest is the nesting of the Little egret on the island of Maraone resulting in the first report for Sicily of a heronry on a marine island. Although this nesting environment has already been established in Sardinia, it should be emphasized that until now the establishment of a heronry has never been detected on an islet so far from the mainland.