Search results for "PEM"
showing 10 items of 623 documents
Conoscere per conservare e valorizzare. Le masserie quale elemento di sviluppo per il territorio delle Madonie
2020
Le développement du concept d’intelligence territoriale en Europe
2011
International audience
Abstract OT-31-01: A phase II study to evaluate the efficacy and safety of pembrolizumab plus carboplatin in BRCA-related metastatic breast cancer: P…
2021
Abstract Background Considering the high proportion of tumor-infiltrating lymphocytes (TILs) in BRCA-related breast cancer, we expect that PD-1 pathway is highly expressed and PD-1 antagonist pembrolizumab could provide clinical activity in this kind of tumor. Furthermore, BRCA-related breast cancers are known to be more sensitive to platinum-derived drugs. Thus the association between Pembrolizumab and Carboplatin in metastatic BRCA-related breast cancer seems to be active in this setting of patients. This study will evaluate the safety and the efficacy of Pembrolizumab associated with Carboplatin in BRCA mutated or with unknown mutations metastatic breast cancer patients. Study and Statis…
Determination of quinolone residues in chicken and fish by capillary electrophoresis-mass spectrometry
2006
A specific pressure-assisted CE-MS method is described for the analysis of five quinolone residues. MS using a single quadrupole is compared with multiple-stage MS using a quadrupole IT (QIT-MS(n)). The procedure involves a common sample preparation by SPE on disposable cartridges. The most suitable electrolyte is 60 mM (NH(4))(2)CO(3) at pH 9.2. Single quadrupole does not provide enough fragmentation to confirm identities according to the current legislation. However, QIT-MS(n) achieves selective fragmentation. Using this method, danofloxacin, enrofloxacin, flumequine, ofloxacin, and pipemidic acid are analyzed in fortified samples of chicken and fish. Recoveries at levels of 50 ng/g were …
Éducation thérapeutique structurée par les pairs éducateurs dans le diabète de type 2 au Mali
2016
International audience; Les pays en développement sont confrontés à des ressources financières et humaines limitées, malgré les besoins importants et les défis de santé multiples. Plus de 75% des personnes atteintes de diabète dans le monde vivent dans des pays en développement. En Afrique, le nombre de personnes atteintes de diabète devrait doubler dans les 30 prochaines années.Les défis à relever pour offrir une éducation visant à permettre aux personnes souffrant d'une condition chronique de la gérer eux-mêmes se situent à trois niveaux : les patients, les prestataires de soins, et les systèmes de santé.Au Mali, après le développement de capacités de prise en charge des patients diabétiq…
The circular economy model in the socio-economic systems of the wood industry : the case of the Tomsk oblast
2021
Using the Circular Economy (CE) model appears to be today a means more and more employed by organizations and public policies to overcome the problem of waste and bring it to a new stage of progress: the one of sustainability. If the issue of diagnosis and the need for a transition to CE is generally no longer discussed, the question of its implementation is all the more so, especially in Russia. Depending on the type of economic sector and the territory considered, an CE strategy cannot be viewed in the same way. Whether in terms of natural resources, labour or capital, different economic factors are brought to interfere in the search for circularity and sustainability. The objective of th…
Natural variation among accessions of Arabidopsis thaliana : beyond the flowering date, what morphological traits are relevant to study adaptation?
2002
International audience
La dynamique entrepreneuriale dans les pays en développement
2020
International audience
La musique dans le Banquet du Faisan d'après Olivier de la Marche
2003
dir. Jean-Marie Cauchies; International audience
The financial crisis and its consequences in European higher education
1990
International audience