Search results for "PEOPLE"
showing 10 items of 1330 documents
Oblicze demograficzne Opola na początku XXI wieku
2019
Opole jako stolica regionu, który w przeszłości zmieniał przynależność państwową i zasięg terytorialny, co skutkowało wielokrotnymi przesunięciami granic wewnętrznych i zewnętrznych oraz ulegał przemianom kulturowo-cywilizacyjnym, współcześnie doświadcza gwałtownych przeobrażeń społecznych. Jednym z głównych jego problemów jest niekorzystny przebieg procesów demograficznych na przełomie XX i XXI w., m.in. depopulacja. Aktualny obraz demograficzny miasta ukształtowało wiele czynników występujących w przeszłości, a zwłaszcza po zakończeniu II wojny światowej, których skutki miasto nadal odczuwa. Celem artykułu było ukazanie depopulacji wraz z towarzyszącymi jej negatywnymi zjawiskami i proces…
Italian familial defective apolipoprotein B patients share a unique haplotype with other Caucasian patients.
2001
Familial defective apolipoprotein (apo) B-100 together with familial hypercholesterolemia are the two common genetic conditions that cause hypercholesterolemia. Familial defective apolipoprotein B-100 is due to mutations around codon 3500 of the apo B gene. The most-characterized mutation is a G>A transition at nucleotide 10,708 that results in the substitution of arginine by glutamine at codon 3500 (Apo B Arg3500Gln). Two other mutations are caused by a C>T transition, one at nucleotide 10,800 (Apo B Arg3531Cys) and the other at nucleotide 10,707 (apo B Arg3500Trp). In the present study we describe three new Italian cases of familial defective apolipoprotein B-100 (Apo B Arg3500Gln), one f…
A homozygous mutation in the TUB gene associated with retinal dystrophy and obesity.
2013
Inherited retinal dystrophies are a major cause of childhood blindness. Here, we describe the identification of a homozygous frameshift mutation (c.1194_1195delAG, p.Arg398Serfs*9) in TUB in a child from a consanguineous UK Caucasian family investigated using autozygosity mapping and whole-exome sequencing. The proband presented with obesity, night blindness, decreased visual acuity, and electrophysiological features of a rod cone dystrophy. The mutation was also found in two of the proband's siblings with retinal dystrophy and resulted in mislocalization of the truncated protein. In contrast to known forms of retinal dystrophy, including those caused by mutations in the tubby-like protein …
The vocationalisation of university programmes in France: its consequences for employability and mobility
2011
In the last three decades, French Universities have offered an increasing number of vocational programmes. More recently, the introduction of vocational Bachelors in 1999 was designed to extend the 'vocationalisation' of French Universities at the Bachelor Level. Using a French follow-up survey on transition from school/ university to work, called "Génération 2004", our paper show that vocational higher education graduates from 2004 cohort entered the labour market in better conditions than their predecessors (from 2010 cohort). In addition, compared with graduates from shorter higher education courses, job opportunities for vocational Bachelor graduates tended to be more stable and better …
The impact of long-term care needs on the socio-economic deprivation of older people and their families: A scoping review protocol
2021
Abstract BackgroundPopulation ageing, constantly on the increase in all countries worldwide, has long been the object of scientific research from several perspectives, including multi and interdisciplinary approaches. This scoping review aims to investigate the socio-economic consequences of older people’s poor health on their own economic conditions and those of their families. This study aims to: a) map the main concepts that characterise the body of literature pertaining to this issue; b) identify conceptual gaps or unexplored research areas to be addressed; c) delve into the ways of arguing about the difficulties that affect a large number of families with older members to care for, esp…
The Meaning of a “Sense of Community” in a Finnish Senior Co-Housing Community
2015
In the foreseeable future, alternative housing options will be needed to meet the needs of and answer to the wishes of older people. Co-housing schemes are developed to fulfill the need for a housing type that provides mutual support and social contacts while alleviating the isolation and loneliness often experienced in ordinary neighborhoods. This study on a senior co-housing community in Finland asked what a “sense of community” meant to the residents and how a sense of community becomes visible in daily life. For these residents, a sense of community meant not only living with like-minded people but also communal activities, doing things together, learning from each other, and having rec…
Elderly Parents’ Need for Help and Adult Children's Moving Decisions
2015
Recent changes in Finnish welfare policies have increased the need for family involvement in eldercare. This article uses qualitative interviews to study working adult daughters’ reasons for moving in with their parent(s). Coresidence was linked to the parents’ need for support, but also to the daughters’ life situations, family histories, the availability of welfare services, and cultural norms and values. The interviewees used the “familist” and “independent life” discourses in their speech. The familist discourse was used to argue for coresidence as a natural continuation of family traditions and life history, whereas the independent life discourse was used to legitimize the need for alt…
Teacher Agency and Futures Thinking
2022
Problems encountered in top-down school reforms have repeatedly highlighted the significance of teachers’ agency in educational change. At the same time, temporality has been identified as a key element in teachers’ agency, with teachers’ beliefs about the future and experiences of the past shaping their agentic orientations. However, research on teachers’ future orientations is typically limited to short-term trajectories, as opposed to long-term visions of education. To address this, we draw on a futures studies perspective to give more explicit attention to teachers’ long-term visions of their work. We argue that the method of future narratives, already well…
Let's End HepC: modelling public health epidemiological policies applied to Hepatitis C in Spain
2022
Background: The WHO has defined international targets toward the elimination of hepatitis C by 2030. Most countries cannot be on track to achieve this goal unless many challenges are surpassed. The Let's End HepC (LEHC) tool aims to contribute to the control of hepatitis C. The innovation of this tool combines the modelling of public health policies (PHP) focused on hepatitis C with epidemiological modelling of the disease, obtaining a unique result that allows to forecast the impact of policy outcomes. The model was applied to several countries, including Spain.Methods: To address the stated objective, we applied the “Adaptive Conjoint Analysis” for PHP decision-making and Markov Chains in…
Alternative ways of expressing FEV1 and mortality in elderly people with and without COPD
2013
Expressing forced expiratory volume in 1 s (FEV1) as % predicted relies on the assumption of proportional variability and generalisability of prediction equations that may be unrealistic, especially for elderly people. We evaluated the prognostic implications of alternative ways of expressing FEV1. We enrolled 318 patients with chronic obstructive pulmonary disease (COPD) and 475 controls in the Salute Respiratoria nell'Anziano (SARA) study. The risk for 5-, 10- and 15-year mortality associated with FEV1 was studied by expressing FEV1 % pred, standardised by height cubed (FEV1 · Ht(-3)) and as a multiple of the sex-specific first percentile (FEV1 quotient (FEV1Q)). In the group with COPD, t…