Search results for "PERFORMANCE"

showing 10 items of 4457 documents

Second-line chemotherapy in advanced pancreatic carcinoma: a multicenter survey of the Gruppo Oncologico Italia Meridionale on the activity and safet…

2007

Background: In daily clinical practice second-line chemotherapy (SLCT) is frequently given to patients with advanced pancreatic cancer failing gemcitabine-based first-line chemotherapy without solid scientific support. Patients and methods: A retrospective survey was carried out including 42 patients. Patients received standard FOLFOX4 regimen biweekly until progression or unacceptable toxicity. Results: Six partial responses (14%) and 16 stabilizations (38%) were recorded for a tumor growth control rate of 57%. The median time to progression (TtP) was 4 months (range 1–7 months), and median overall survival (OS) was 6.7 months (range 2–9 months). A stabilization of performance status (PS) …

AdultMalemedicine.medical_specialtyPancreatic diseaseOrganoplatinum Compoundsmedicine.medical_treatmentLeucovorinAdenocarcinomaInternal medicinePancreatic cancerAntineoplastic Combined Chemotherapy ProtocolsMedicineHumansAgedRetrospective StudiesChemotherapyPerformance statusbusiness.industryCancerHematologyMiddle Agedmedicine.diseaseChemotherapy regimenGemcitabineDrug Resistance MultipleSurgeryPancreatic NeoplasmsFOLFOX4 regimen pancreatic carcinoma second-line chemotherapyRegimenOncologyChemotherapy AdjuvantDrug Resistance NeoplasmFemaleFluorouracilbusinessmedicine.drug
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Subcortical ischaemic changes in young hypertensive patients: frequency, effect on cognitive performance and relationship with markers of endothelial…

2007

Information on subcortical ischaemic changes (SIC) in young hypertensive patients is scarce. We evaluated the frequency of SIC at magnetic resonance imaging (MRI), the possible effect on cognition of these patients, and the role of plasma markers known as indicators of endothelial and haemostatic activation. Inclusion criteria were age <or=54 years, hypertension for at least 2 years and absence of cerebrovascular disease or other conditions possibly related to SIC. Patients with SIC at MRI and two control groups (matched for age, sex and education) of hypertensive patients without SIC and non-hypertensive healthy subjects underwent an extensive neuropsychological examination and evaluation …

AdultMalemedicine.medical_specialtyPathologyEndotheliumNeuropsychological TestsBrain IschemiaCognitionstomatognathic systemVon Willebrand factorInternal medicinemedicineHumansAge FactorEffects of sleep deprivation on cognitive performanceEndothelial dysfunctionHemostasisbiologymedicine.diagnostic_testbusiness.industryAge FactorsNeuropsychologyBrainMagnetic resonance imagingBiomarkerHemostasiMiddle Agedmedicine.diseaseMagnetic Resonance ImagingBlood pressuremedicine.anatomical_structureNeurologyHemostasisHypertensionCardiologybiology.proteinFemaleEndothelium VascularNeurology (clinical)businessBiomarkersHumanEuropean Journal of Neurology
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Comparison of131I-metaiodobenzylguanidine scintigraphy with urinary and plasma catecholamine determinations in the diagnosis of pheochromocytoma

1985

In a retrospective study of 31 patients with suspected pheochromocytoma we examined the preoperative results of 131I-metaiodobenzylguanidine (131-I-MIBG) scintigraphy and a fluorimetric urine catecholamine determination test. An additional radioenzymatic plasma catecholamine determination test was performed in 25 patients. In 14 of the 31 patients the diagnosis of pheochromocytoma was later histologically confirmed. In the remaining 17 patients the suspected diagnosis was finally rejected after a clinical decision had been made on the basis of clinical history, symptoms, laboratory and imaging tests. 131-I-MIBG scintigraphy apparently had a very high specificity (no false-positive results a…

AdultMalemedicine.medical_specialtyPathologyUrinary systemAdrenal Gland NeoplasmsUrologyPheochromocytomaUrineScintigraphyHigh-performance liquid chromatographyPheochromocytomaCatecholaminesPathognomonicDrug DiscoverymedicineHumansRadionuclide ImagingGenetics (clinical)AgedRetrospective Studiesmedicine.diagnostic_testIodobenzenesbusiness.industryRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.disease3-IodobenzylguanidineCatecholamineMolecular MedicineFemalebusinessmedicine.drugKlinische Wochenschrift
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A Submaximal Running Test With Post-Exercise Cardiac Autonomic And Neuromuscular Function In Monitoring Endurance Training Adaptation

2016

Vesterinen, V, Nummela, A, Laine, T, Hynynen, E, Mikkola, J, and Häkkinen, K. A submaximal running test with postexercise cardiac autonomic and neuromuscular function in monitoring endurance training adaptation. J Strength Cond Res 31(1): 233-243, 2017-The aim of this study was to investigate whether a submaximal running test (SRT) with postexercise heart rate recovery (HRR), heart rate variability (HRV), and countermovement jump (CMJ) measurements could be used to monitor endurance training adaptation. Thirty-five endurance-trained men and women completed an 18-week endurance training. Maximal endurance performance and maximal oxygen uptake were measured every 8 weeks. In addition, SRTs wi…

AdultMalemedicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationAdaptation (eye)030204 cardiovascular system & hematologyAutonomic Nervous SystemjuoksuYoung Adult03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationHeart RateEndurance trainingHeart raterunningHumansMedicineHeart rate variabilityharjoitteluOrthopedics and Sports Medicineta315heart rate recoveryMonitoring Physiologiccountermovement jumptrainingbusiness.industryheart rate variabilityVO2 max030229 sport sciencesGeneral MedicineMiddle AgedAdaptation PhysiologicalRecovery stageTest (assessment)Exercise TestPhysical EndurancePhysical therapyFemalebusinessTraining programhuman activitiesperformance
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Effects of an Electrostimulation Training Program on Strength, Jumping, and Kicking Capacities in Soccer Players

2010

The present study investigated the influence of a 5-week electrostimulation (EMS) training program on muscular strength, kicking velocity, sprint, and vertical jump performance in soccer players. Twenty amateur soccer players participated in the study, 10 in the electrostimulated group and the remaining 10 in a control group. Electrostimulation was applied on the quadriceps muscles over 5 weeks. Subjects were tested before, during (wk-3), and after (wk-5) the EMS training program. Maximal voluntary contraction using different contraction mode (i.e., eccentric, concentric, and isometric), vertical jump height, sprint running for 10 m, and ball speed were examined. We observed an increase in …

AdultMalemedicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationIsometric exerciseAthletic PerformanceConcentricPhysical strengthmedicine.disease_causeVertical jumpJumpingSoccermedicineHumansEccentricOrthopedics and Sports MedicineMuscle StrengthMuscle SkeletalMathematicsPhysical Education and TrainingGeneral MedicineElectric StimulationSprintPhysical therapyTraining programhuman activitiesJournal of Strength and Conditioning Research
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The effects of creatine supplementation on muscular performance and body composition responses to short-term resistance training overreaching

2003

To determine the effects of creatine supplementation during short-term resistance training overreaching on performance, body composition, and resting hormone concentrations, 17 men were randomly assigned to supplement with 0.3 g/kg per day of creatine monohydrate (CrM: n=9) or placebo (P: n=8) while performing resistance exercise (5 days/week for 4 weeks) followed by a 2-week taper phase. Maximal squat and bench press and explosive power in the bench press were reduced during the initial weeks of training in P but not CrM. Explosive power in the bench press, body mass, and lean body mass (LBM) in the legs were augmented to a greater extent in CrM ( P<or=0.05) by the end of the 6-week period…

AdultMalemedicine.medical_specialtyPhysiologyStrength trainingAdministration OralBlood PressureCreatineBench presschemistry.chemical_compoundHeart RatePhysiology (medical)Internal medicinemedicineHumansOrthopedics and Sports MedicineMuscle SkeletalPhysical Education and Trainingbusiness.industryOvertrainingFree androgen indexPublic Health Environmental and Occupational HealthGeneral MedicineCreatineOverreachingmedicine.diseaseAdaptation PhysiologicalHormonesEndocrinologychemistryDietary SupplementsBody CompositionPhysical EnduranceLean body massCreatine MonohydratebusinessPsychomotor PerformanceMuscle ContractionEuropean Journal of Applied Physiology
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Motor learning without doing: trial-by-trial improvement in motor performance during mental training.

2010

Although there is converging experimental and clinical evidences suggesting that mental training with motor imagery can improve motor performance, it is unclear how humans can learn movements through mental training despite the lack of sensory feedback from the body and the environment. In a first experiment, we measured the trial-by-trial decrease in durations of executed movements (physical training group) and mentally simulated movements (motor-imagery training group), by means of training on a multiple-target arm-pointing task requiring high accuracy and speed. Movement durations were significantly lower in posttest compared with pretest after both physical and motor-imagery training. …

AdultMalemedicine.medical_specialtyPhysiologyeducationSensory systemDevelopmental psychologyTask (project management)Young AdultPhysical medicine and rehabilitationMotor imageryMental practiceFeedback SensorymedicineHumansLearningMovement (music)General NeuroscienceTraining (meteorology)Biomechanical PhenomenaDuration (music)Practice PsychologicalImaginationFemalePsychologyMotor learningPsychomotor PerformanceJournal of neurophysiology
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Effects of cumulative sleep restriction on self-perceptions while multitasking

2012

Summary This study addressed a rarely studied question of self-perceptions of performance and overall functional state during cumulative sleep restriction and the ensuing recovery period. Twenty healthy male volunteers, aged 19–29 years, were divided into a sleep restriction group (n = 13) and a control group (n = 7). On the first 2 nights, the sleep restriction group had an 8-h sleep opportunity that was restricted to 4 h for the next 5 nights, and then restored to 8 h for the last 2 nights. The control group had an 8-h sleep opportunity each night. Each day participants accomplished 50-min multitask sessions and gave self-ratings in their connection. Similar to our previous findings on mu…

AdultMalemedicine.medical_specialtyPolysomnographyCognitive Neurosciencemedia_common.quotation_subjectMental fatigueSleep inertiaDisorders of Excessive SomnolenceNeuropsychological TestsAudiologyTask (project management)Developmental psychologyYoung Adult03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineSleep debtPerceptionTask Performance and AnalysismedicineHumansHuman multitaskingta515Fatiguemedia_commonSleep restrictionta3141ta3142General MedicineSelf Concept030228 respiratory systemSleep DeprivationSleep (system call)SleepPsychologyPsychomotor Performance030217 neurology & neurosurgeryJournal of Sleep Research
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Recovery during and after a simulated multi-day tennis tournament: Combining active recovery, stretching, cold-water immersion, and massage intervent…

2021

The aim of this study was to investigate the effects of a mixed-method recovery intervention (MMR) consisting of active recovery, stretching, cold-water immersion, and massage on physical, technical, physiological, and perceptual recovery during and after a five-day simulated tennis tournament. Nine competitive male tennis players (age, 24.6±4.2 years) with national ranking positions (German Tennis Federation) and Universal Tennis Ratings between approximately 11 to 13 participated in two singles tennis tournaments, which were separated by a three-month washout period. During the tournaments, participants played five two-and-a-half-hour competitive singles tennis match on five consecutive d…

AdultMalemedicine.medical_specialtyPsychological intervention030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationAthletic Performance03 medical and health sciencesYoung Adult0302 clinical medicineImmersionmedicineHumansOrthopedics and Sports MedicineTournamentBlood markersMassageMassagebiologyAthletesWater030229 sport sciencesGeneral MedicineMyalgiaOverreachingbiology.organism_classificationSprintWater immersionTennisPhysical therapyPsychologyhuman activitiesEuropean journal of sport science
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Monitoring cognitive changes: Psychometric properties of six cognitive tests

2004

Objectives. Repeated neuropsychological assessments are often used to monitor change in cognitive functioning over time. Thus, knowledge about the reliability and stability of neuropsychological tests and the effects of age and IQ is of paramount importance. In this study we document, for six cognitive tests: test-retest reliabilities, practice effects, reliable change (RC) indices corrected for practice, and the impact of premorbid IQ and age. Design. A sample of 188 normal adults (aged 40-70 years) were administered, on two occasions, one or more of the following tests: the Graded Naming Test (GNT), the Silhouettes Test, two tests of verbal fluency, the Modified Wisconsin Card Sorting Tes…

AdultMalemedicine.medical_specialtyPsychometricsBRAIN-INJURYTest validityNeuropsychological TestsAudiologyNAMING TESTNational Adult Reading TestSeverity of Illness IndexMEMORY TESTDevelopmental psychologyDEMOGRAPHIC-VARIABLESTEST-PERFORMANCEmedicineHumansLONGITUDINAL PROFILESAchievement testVerbal fluency testAgedCARD SORTING TESTSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaIntelligence quotientmedicine.diagnostic_testReproducibility of ResultsGeneral MedicineNeuropsychological testMiddle AgedCognitive testTest (assessment)ALZHEIMERS-DISEASEVERBAL FLUENCYClinical PsychologyPractice PsychologicalFemaleTEST-RETEST RELIABILITYCognition DisordersPsychologyGraded Naming Test Silhouettes Test Verbal fluency tests Modified Wisconsin Card Sorting Test New Symbol Digit Test National Adult Reading Test (NART)
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