Search results for "PERTURBATIONS"
showing 10 items of 25 documents
The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor
2021
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-stress-regulated protein exhibiting cytoprotective properties through a poorly understood mechanism in various in vitro and in vivo models of neuronal and non-neuronal damage. Although initially characterized as a secreted neurotrophic factor for midbrain dopamine neurons, MANF has recently gained more interest for its intracellular role in regulating the ER homeostasis, including serving as a cofactor of the chaperone glucose-regulated protein 78 (GRP78). We aimed for a better understanding of the neuroprotective mechanisms of MANF. Here we show for the first time that MANF promotes the survival of …
Cyclicity of common slow–fast cycles
2011
Abstract We study the limit cycles of planar slow–fast vector fields, appearing near a given slow–fast cycle, formed by an arbitrary sequence of slow parts and fast parts, and where the slow parts can meet the fast parts in a nilpotent contact point of arbitrary order. Using the notion slow divergence integral, we delimit a large subclass of these slow–fast cycles out of which at most one limit cycle can perturb, and a smaller subclass out of which exactly one limit cycle will perturb. Though the focus lies on common slow–fast cycles, i.e. cycles with only attracting or only repelling slow parts, we present results that are valid for more general slow–fast cycles. We also provide examples o…
Tropical Temperate Toughs over southern Africa : mechanisms and evolution in response to climate change (2010-2099)
2014
In the Southern Hemisphere, Southern Africa and the south-west Indian Ocean are one of the three preferred regions where interactions between the tropics and midlatitudes develop. This is the South Indian Convergence Zone (SICZ), where northwest-southeast oriented cloud bands form at the synoptic scale (between 3 and 5 days). These bands are mainly found during the austral summer and are commonly referred to as tropical temperate troughs (TTTs). This research aims at improving our knowledge related to TTTs, with a study on the dynamics associated with these systems, and an analysis of their possible evolution during the 21st century.The first part of this thesis aims at identifying favorabl…
GW190412: Observation of a binary-black-hole coalescence with asymmetric masses
2020
LIGO Scientific Collaboration and Virgo Collaboration: et al.
Un nouveau modèle de transcodage des nombres : aspects développementaux, neuropsychologiques et computationnels
2005
Ce texte est un rapport de fin de recherche issu de l'ACI cognitique.; L'objectif du projet était de produire et valider empiriquement un modèle développemental de transcodage des nombres de leur forme verbale (orale ou écrite) vers leur forme en chiffres. Le modèle, baptisé ADAPT (A Developmental Asemantic Procedural Transcoding model), est un système de production qui transforme un input verbal en chaîne de chiffres par la mise en œuvre de procédures. Celles-ci lisent le contenu de la mémoire de travail et le transforment en récupérant en mémoire à long terme des associations entre formes verbales et formes en chiffres. L'originalité du modèle est sa capacité à apprendre à partir de son f…
Toeplitz band matrices with small random perturbations
2021
We study the spectra of $N\times N$ Toeplitz band matrices perturbed by small complex Gaussian random matrices, in the regime $N\gg 1$. We prove a probabilistic Weyl law, which provides an precise asymptotic formula for the number of eigenvalues in certain domains, which may depend on $N$, with probability sub-exponentially (in $N$) close to $1$. We show that most eigenvalues of the perturbed Toeplitz matrix are at a distance of at most $\mathcal{O}(N^{-1+\varepsilon})$, for all $\varepsilon >0$, to the curve in the complex plane given by the symbol of the unperturbed Toeplitz matrix.
Tropical Temperate Toughs over southern Africa: mechanisms and evolution in response to climate change
2015
In the Southern Hemisphere, Southern Africa and the south-west Indian Ocean are one of the three preferred regions where interactions between the tropics and midlatitudes develop. This is the South Indian Convergence Zone (SICZ), where northwest-southeast oriented cloud bands form at the synoptic scale (between 3 and 5 days). These bands are mainly found during the austral summer and are commonly referred to as tropical temperate troughs (TTTs). This research aims at improving our knowledge related to TTTs, with a study on the dynamics associated with these systems, and an analysis of their possible evolution during the 21st century.The first part of this thesis aims at identifying favorab…
Robust Adaptive H∞ Synchronization of Master-Slave Systems with Discrete and Distributed Time-Varying Delays and Nonlinear Perturbations
2011
Author's version of a chapter published in the book: Proceedings of the 18th IFAC World Congress 2011. Also available from the publisher at: http://dx.doi.org/10.3182/20110828-6-IT-1002.03116
Search for eccentric binary black hole mergers with advanced LIGO and advanced Virgo during their first and second observing runs
2019
When formed through dynamical interactions, stellar-mass binary black holes may retain eccentric orbits ($e>0.1$ at 10 Hz) detectable by ground-based gravitational-wave detectors. Eccentricity can therefore be used to differentiate dynamically-formed binaries from isolated binary black hole mergers. Current template-based gravitational-wave searches do not use waveform models associated to eccentric orbits, rendering the search less efficient to eccentric binary systems. Here we present results of a search for binary black hole mergers that inspiral in eccentric orbits using data from the first and second observing runs (O1 and O2) of Advanced LIGO and Advanced Virgo. The search uses min…
CMB spectral distortions in generic two-field models
2017
We investigate the CMB $\mu$ distortion in models where two uncorrelated sources contribute to primordial perturbations. We parameterise each source by an amplitude, tilt, running and running of the running. We perform a detailed analysis of the distribution signal as function of the model parameters, highlighting the differences compared to single-source models. As a specific example, we also investigate the mixed inflaton-curvaton scenario. We find that the $\mu$ distortion could efficiently break degeneracies of curvaton parameters especially when combined with future sensitivity of probing the tensor-to-scalar ratio $r$. For example, assuming bounds $\mu < 0.5 \times 10^{-8}$ and $r<0.0…