Search results for "PHARMACOLOGY"
showing 10 items of 8885 documents
Organisaation merkityksentäminen sairaalajohtoryhmäkokouksissa
2016
Kokouksia järjestetään kaikissa organisaatioissa ja yhteiskunnissa ja ne vievät valmisteluineen suuren osan erityisesti johtajien työajasta. Tästä huolimatta kokousten roolia osana organisaation prosesseja on tutkittu ja jäsennetty teoreettisesti verrattain vähän. Tämä tutkimus keskittyy sairaalajohtoryhmien kokousvuorovaikutuksessa tapahtuvaan sairaalaorganisaation merkityksentämiseen (sensemaking). Tutkimuksen tavoite on ymmärtää johtoryhmien kokousvuorovaikutuksessa tapahtuvan sairaalaorganisaation merkityksentämisen roolia osana kokouksia ja koko organisaation toimintaa. Aineistona on kymmenen videoitua kokousta kahdelta eri organisaatiotasolta. Aineiston analyysi perustui vuorovaikutus…
Vuorovaikutus sairaalajohtoryhmien kokouksissa
2018
Lectio praecursoria viestinnän väitöskirjaksi tarkoitetun tutkimuksen Vuorovaikutus sairaalajohtoryhmien kokouksissa tarkastustilaisuudessa Jyväskylän yliopistossa 27.10.2018. Vastaväittäjänä toimi vanhempi yliopistonlehtori, dosentti Pekka Pälli (Aalto yliopisto) ja kustoksena yliopistonlehtori, FT Leena Mikkola (Jyväskylän yliopisto). nonPeerReviewed
Sairaalatyöyhteisön hallinnollisessa vuorovaikutuksessa rakennetaan työn resursseja ja työn yhteisyyttä
2018
Lectio praecursoria viestinnän väitöskirjaksi tarkoitetun tutkimuksen Hallinnollinen vuorovaikutus sairaalatyöyhteisössä tarkastustilaisuudessa Jyväskylän yliopistossa 6.4.2018. Vastaväittäjänä toimi yliopistonlehtori, dosentti Tuula-Riitta Välikoski (Tampereen yliopisto) ja kustoksena yliopistonlehtori, FT Leena Mikkola (Jyväskylän yliopisto). nonPeerReviewed
LA IMPORTANCIA DEL DINERO EN LA ELECCIÓN LABORAL
2014
Resumen: El objetivo fundamental del presente articulo es identificar los factores motivadores del trabajo entre los futuros directivos y trabajadores y reflexionar desde un punto de vista tanto academico como profesional sobre la importancia del dinero como factor motivador. Para ello, hemos tomado a estudiantes universitarios, en su faceta de futuros trabajadores; se concluye que el dinero por si solo no motiva y que es necesario encontrar aquel grupo de factores que motivan a los trabajadores con el objetivo de conseguir el maximo rendimiento. Los resultados nos permiten concluir que no debemos motivar tan solo con el dinero o admitiendolo como principal elemento motivacional. Palabras c…
Epigenetic regulation of sex differences in susceptibility to stress
2017
Under current diagnostics depression and stress related mood disorders have a higher occurrence in women than men. Little is known of the biological mechanisms contributing to these sex differences and how they may impact potential new therapeutics. Here we examine how DNA methylation contributes to sex specific stress vulnerability in adult animals. Mice of both sexes were exposed to variable stress and given a behavioral test battery to examine stress sensitivity. Female mice expressed depressionassociated behavior across all tests stress exposure whereas males were behaviorally resilient. Markers of pre and post-synaptic plasticity and spine morphology were examined using a combination o…
Valorization of Side Stream Products from Sea Cage Fattened Bluefin Tuna (Thunnus thynnus): Production and In Vitro Bioactivity Evaluation of Enriche…
2022
The valorization of side streams from fishery and aquaculture value-chains is a valuable solution to address one of the challenges of the circular economy: turning wastes into profit. Side streams produced after filleting of sea cage fattened bluefin tuna (Thunnus thynnus) were analyzed for proximate composition and fatty acid profile to evaluate the possibility of producing tuna oil (TO) as a valuable source of ω-3 polyunsaturated fatty acids (PUFA) and testing its bioactivity in vitro. Ethyl esters of total fatty acids (TFA), obtained from TO, were pre-enriched by urea complexation (PUFA-Ue) and then enriched by short path distillation (SPD) up to almost 85% of the PUFA fraction (PU…
Microneedle-Based Delivery: An Overview of Current Applications and Trends
2020
Microneedle arrays (MNA) are considered as one of the most promising resources to achieve systemic effects by transdermal delivery of drugs. They are designed as a minimally invasive, painless system which can bypass the stratum corneum, overcoming the potential drawbacks of subcutaneous injections and other transdermal delivery systems such as chemical enhancers, nano and microparticles, or physical treatments. As a trendy field in pharmaceutical and biomedical research, its applications are constantly evolving, even though they are based on very well-established techniques. The number of molecules administered by MNA are also increasing, with insulin and vaccines administration being the …
Assessment of the moisturizing potential of a two-phase topical care product containing vegetable oils, glycerin, panthenol, and sodium hyaluronate -…
2022
The presence of moisturizing substances and lipid substances determines the integrity of the epidermis cells and their barrier functions because it protects the interior of the body against environmental changes: temperature, humidity, ultraviolet radiation, pollution, and the effects of detergents. In this study, we performed a non-invasive, preliminary evaluation of the effects of a biphasic facial skin care product containing plant oils, hyaluronic acid, glycerin, and panthenol on skin hydration levels and transepidermal water loss compared to a control group using only shea butter. The topical care product formed as a two-phase emulsion was tested. The research was carried out with the …
Synthesis and Biological Evaluation of a Multiantigenic Tn/TF-Containing Glycopeptide Mimic of the Tumor-Related MUC1 Glycoprotein
2006
Advances in Nanoliposomes Production for Ferrous Sulfate Delivery
2020
In this study, a continuous bench scale apparatus based on microfluidic fluid dynamic principles was used in the production of ferrous sulfate-nanoliposomes for pharmaceutical/nutraceutical applications, optimizing their formulation with respect to the products already present on the market. After an evaluation of its fluid dynamic nature, the simil-microfluidic (SMF) apparatus was first used to study the effects of the adopted process parameters on vesicles dimensional features by using ultrasonic energy to enhance liposomes homogenization. Subsequently, iron-nanoliposomes were produced at different weight ratios of ferrous sulfate to the total formulation components (0.06, 0.035, 0.02, an…