Search results for "PHASES"

Phases transitions in complexe oxides with perovskite structure : case system (1-x)Na0,5Bi0,5TiO3 - xCaTiO3

2015

The solid solutions (1-x)Na0,5Bi0,5TiO3 (NBT) – xCaTiO3 (CT) were studied by X-ray diffraction, Raman spectroscopy, scanning electron microscopy, impedance spectroscopy and DSC. These materials have a perovskite crystalline structure. This study reveals not only the complexity but also the richness of physical phenomena in these compounds: phases transitions sequences, the Ca2+ effect on the physical-chemistry properties and the relation between dielectric properties and crystalline structure. Thereby, (1-x)NBT – xCT solid solutions (0 ≤ x ≤ 1.00) were synthesized by chemical solid route, then they were sintered by a particular procedure in order to avoid sodium and bismuth volatilization. …

NEONAX trial: Neoadjuvant plus adjuvant or only adjuvant nab-paclitaxel plus gemcitabine for resectable pancreatic cancer, a phase II study of the AI…

2019

4128 Background: Survival in pancreatic cancer (PDAC) is still poor even after curatively intended resection. Perioperative treatment approaches improve outcome in various tumor entities. Data on perioperative treatment in resectable PDAC are limited and there is a debate whether neoadjuvant treatment might impair subsequent surgery by adding perioperative morbidity or mortality. Methods: NEONAX is a randomized phase II study (planned 166 patients) of perioperative gemcitabine/nab-paclitaxel (Arm A: 2 pre- and 4 post-operative cycles, Arm B: 6 cycles adjuvant) for patients with primarily resectable PDAC. Primary objective is DFS at 18 months after randomization. Secondary objectives are 3-…

Comparative modelling study on enantioresolution of structurally unrelated compounds with amylose-based chiral stationary phases in reversed phase li…

2020

[EN] Polysaccharide-based chiral stationary phases (CSPs) are the most used chiral selectors in HPLC. These CSPs can be used in normal, polar organic and aqueous-organic mobile phases. However, normal and polar organic mobile phases are not adequate for chiral separation of polar compounds, for the analysis of aqueous samples and for MS detection. In these situations, reversed phase conditions, without the usual non-volatile additives incompatible with MS detection, are preferable. Moreover, in most of the reported chiral chromatographic methods, retention is too large for routine work. In this paper, the chiral separation of 53 structurally unrelated compounds is studied using three commer…

Metilazione del DNA in artrite reumatoide

2005

Lo stato di metilazione del DNA genomico e del gene PTHrP è stato valutato con tecniche molecolari e citogenetiche in artrite reumatoide (AR), patologia autoimmune caratterizzata anche da alta incidenza di linfomi e da ipercalcemia per overespressione del gene PTHrP. La metilazione del DNA, infatti, ha un ruolo critico nello sviluppo delle malattie neoplastiche; il gene PTHrP avendo tre promotori uno dei quali contiene un’isola CpG è un buon candidato per la deregolazione da alterato pattern di metilazione locale. Le indagini sulla metilazione genomica, condotte su DNA estratto da sangue periferico di pazienti e di donatori e amplificato in reazioni di Methylation-Sensitive Arbitrarily Prim…

Dicationic Organic Salts: our recent journey in their properties and applications

2014

The role of extracellular polymeric substances (EPS) on aerobic granules formation: comparison between a case of synthetic wastewater supply and anot…

2015

The paper focused on the evolution of extracellular polymeric substances (EPSs) content during the granulation process in two Granular Sequencing Batch Airlift Reactors (GSBAR) (3,5 L) fed with synthetic and industrial wastewater. Results showed that EPSs, in particular proteins (PN) were mainly produced during the feast phase because of high substrate availability, especially under conditions of metabolic stress. Than EPSs content reduced during the famine period. More in detail, during the granulation process, a greater polysaccharides (PS) consumption occurred in both reactors, while PN content reduced significantly only in R2. As a result PN/PS ratio increased significantly during granu…

Thermodynamics and Structure of Plate-Like Particle Dispersions

2012

A considerable amount of mineral particles are found to have a plate-like shape. The work in this thesis concerns theoretical investigations, using a Monte Carlo method, of the properties of such particles in aqueous solutions. The objectives were first to create a model that could capture the essential physics of clay suspensions and also to understand the role of thermodynamics in certain chemical processes. For all investigations, the results are related to experimental studies. The acid-base behavior of clays have been studied, using the primitive model, and an excellent agreement between simulated and experimental results was found. The formation of gel phases as a function of the char…

Nuove ricerche a Solunto (2021)

2021

New researches in Solunto (2021) · The paper presents an overview of the ongoing researches in Solunto by the University of Palermo. In 2021 stratigraphical sondages were undertaken in two areas of the town: 1) in the great sanctuary above the theatre, in the frame of a major project aimed at addressing several still unresolved issues. That area, as a matter of fact, has never been considered as a whole; the sacred buildings have not been studied, and their mutual relationships and the links with the adjacent terraces have never been properly examined; 2) in the North Baths near the agora, as a corollary of the systematic study of water management, some sondages were made by G. Polizzi. Fin…

Sorafenib In Combination with Standard Induction and Consolidation Therapy In Elderly AML Patients: Results From a Randomized, Placebo-Controlled Pha…

2010

Abstract Abstract 333 Background: Standard chemotherapy for elderly AML patients results in a median overall survival of only about one year. Case reports and early phase I/II data have shown that the kinase inhibitor Sorafenib might show clinical benefit for Flt3-ITD-positive AML patients (Metzelder S Blood 2009; 113:6567) and that its addition to standard chemotherapy is feasible (Ravandi F JCO 2010; 28:1856). Sorafenib is a potent Raf, c-Kit and FLT3 inhibitor that may also affect AML blasts and bone marrow (BM) stroma cells via VEGFR and PDGFR-β inhibition. Therefore, we performed a multicenter, randomized, placebo-controlled, double-blind phase II trial in elderly (>60 y) AML pa…

Small clusters with anisotropic antiferromagnetic exchange in a magnetic field

2004

We consider small symmetric clusters of magnetic atoms (spins) with anisotropic exchange interaction between the atoms in a magnetic field at zero temperature. The inclusion of the anisotropy leads to a wealth of different phases as a function of the applied magnetic field. These are not phases in the thermodynamic sense with critical properties but rather physical structures with different arrangements of the spins and hence different symmetries. We study the spatial symmetry of these phases, for the classical and quantum cases. Results are presented mainly for three frustrated systems, the triangle, the tetrahedron and the five-atom ring, which have many interesting features. In the class…