Search results for "PHG"

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Preparation of Polymeric Nanoparticles by Photo-Crosslinking of an Acryloylated Polyaspartamide in w/o Microemulsion

2004

Biodegradable polymeric nanoparticles have been prepared by UV irradiation of an acryloylated water soluble polymer by an inverse microemulsion. The starting polymer was a α,β‐poly(N‐2‐hydroxyethyl)‐D,L‐aspartamide (PHEA) partially functionalized with glycidyl methacrylate (GMA) in order to introduce reactive vinyl groups in the side chain. The PHEA‐GMA copolymer obtained (PHG) was crosslinked by UV irradiation of the inverse microemulsion prepared by mixing an aqueous solution of PHG with propylene carbonate (PC)/ethyl acetate (EtOAc) in the presence of sorbitan trioleate (SPAN 85) as surfactant. Nanoparticles obtained were characterized by FTIR spectrophotometry, transmission electron mic…

inverse microemulsionGlycidyl methacrylatePHGAqueous solutionPolymers and PlasticsChemistryOrganic ChemistryNanoparticleCondensed Matter Physicsacryloylated polyaspartamide inverse microemulsion irradiation nanoparticles PHG photo‐crosslinkingphoto-crosslinkingchemistry.chemical_compoundSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoPolymer chemistryMaterials ChemistryZeta potentialSide chainCopolymernanoparticlesMicroemulsionPhysical and Theoretical ChemistryDrug carrieracryloylated polyaspartamideMacromolecular Chemistry and Physics

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PEPhysical Sciences and Engineering
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LSLife Sciences
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SHSocial Sciences and Humanities
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