Search results for "PID"
showing 10 items of 11585 documents
Transport of Arabidopsis GPI-anchored proteins along the early secretory pathway: Role of GPI-anchor remodelling and p24 proteins
2019
Las proteínas con anclaje GPI son una familia de proteínas que están ancladas a la cara exterior de la membrana plasmática mediante un ancla GPI y se ha visto que juegan un papel clave en plantas. Sin embargo, la maquinaria molecular implicada en el transporte de estas proteínas a la membrana plasmática en plantas es aún desconocida. Las proteínas p24 tienen un papel importante en el control de calidad de proteínas (posiblemente incluyendo las proteínas con anclaje GPI) transportadas entre el Retículo Endoplasmático y el aparato de Golgi. Esta tesis doctoral tiene como objetivo el estudio de la posible implicación de las proteínas p24 en la salida del Retículo Endoplasmático y en la localiz…
Identificación de nuevos biomarcadores de trombosis venosa mediante técnicas ómicas
2022
El tromboembolismo venoso (TEV) es el término conjunto que se adopta para incluir la trombosis venosa profunda (TVP) y el tromboembolismo pulmonar (TEP). El TEV es la tercera enfermedad cardiovascular más común, por detrás del infarto de miocardio y el ictus, y tiene una incidencia aproximada de entre 1-2 casos por 1.000 individuos/año. Estudios de tendencia han mostrado que la incidencia del TEV ha aumentado en las últimas décadas y que es muy probable que lo siga haciendo en los próximos años. El TEV es una enfermedad multifactorial, en la que están implicados tanto factores de riesgo hereditarios como adquiridos. Entre los factores hereditarios, la carga genética se asocia con una alta h…
Lifestyle and Empowerment Techniques in Survivorship of Gynaecologic Oncology (LETSGO study): A study protocol for a multicentre longitudinal interve…
2021
IntroductionThe number of gynaecological cancer survivors is increasing and there is a need for a more sustainable model of follow-up care. Today’s follow-up model is time-consuming and patients have reported unmet needs regarding information about their cancer and strategies for managing the consequences of treatment. The main aim of this study is to assess health-related empowerment—in terms of patient education, psychosocial support, and promotion of physical activity—in a new follow-up model by comparing it to standard follow-up in a quasi-randomised study involving intervention hospitals and control hospitals.Methods and analysisAt the intervention hospitals, patients will be stratifie…
Centrality Dependence of the Charged-Particle Multiplicity Density at Midrapidity in Pb-Pb Collisions at √sNN = 5.02 TeV
2016
The pseudorapidity density of charged particles, dNch=dη, at midrapidity in Pb-Pb collisions has been measured at a center-of-mass energy per nucleon pair of √sNN=5.02 TeV. For the 5% most central collisions, we measure a value of 1943±54. The rise in dNch=dη as a function of √sNN is steeper than that observed in proton-proton collisions and follows the trend established by measurements at lower energy. The increase of dNch=dη as a function of the average number of participant nucleons, hNparti, calculated in a Glauber model, is compared with the previous measurement at √sNN=2.76 TeV. A constant factor of about 1.2 describes the increase in dNch=dη from √sNN=2,76 to 5.02 TeV for all central…
Exploring fast proton transfer events associated with lateral proton diffusion on the surface of membranes
2019
Proton diffusion (PD) across biological membranes is a fundamental process in many biological systems, and much experimental and theoretical effort has been employed for deciphering it. Here, we report on a spectroscopic probe, which can be tightly tethered to the membrane, for following fast (nanosecond) proton transfer events on the surface of membranes. Our probe is composed of a photoacid that serves as our light-induced proton source for the initiation of the PD process. We use our probe to follow PD, and its pH dependence, on the surface of lipid vesicles composed of a zwitterionic headgroup, a negative headgroup, a headgroup that is composed only from the negative phosphate group, or…
Alimentation et vision
2016
Pseudorapidity and transverse-momentum distributions of charged particles in proton–proton collisions at √s = 13 TeV
2016
The pseudorapidity (η) and transverse-momentum (pT) distributions of charged particles produced in proton–proton collisions are measured at the centre-of-mass energy √s = 13 TeV. The pseudorapidity distribution in |η| < 1.8 is reported for inelastic events and for events with at least one charged particle in |η| < 1. The pseudorapidity density of charged particles produced in the pseudorapidity region |η| < 0.5 is 5.31 ± 0.18 and 6.46 ± 0.19 for the two event classes, respectively. The transverse-momentum distribution of charged particles is measured in the range 0.15 < pT < 20 GeV/c and |η| < 0.8 for events with at least one charged particle in |η| < 1. The evolution of the transverse mome…
A control strategy based on intelligent algorithm (PSO) to perform electrical stimulation systems
2017
International audience; Adjusting stimulation parameters using control strategy based on reliable mathematical model that can predict perfectly the muscle response, may improve the efficiency of Functional Electrical Stimulation (FES) systems. In the present project, we investigate the PID control tuning based on the Particle Swarm Optimization (PSO) algorithm at the first time in neuro-muscular systems for updating automatically the stimulation pulse amplitude to track a desired force profiles. In the beginning, The PSO algorithm is used to identify unknown force model parameters. Next, optimal PID gains are found by the same intelligent algorithm to improve the control system. The obtaine…
He kept us out of war? : yleisen mielipiteen vaikutus Woodrow Wilsonin päätöksiin Yhdysvaltain liittymisestä ensimmäiseen maailmansotaan
2003
Dementia in former amateur and professional contact sports participants : population-based cohort study, systematic review, and meta-analysis
2023
Background Although there is growing evidence that former professional athletes from sports characterised by repetitive head impact subsequently experience an elevated risk of dementia, the occurrence of this disorder in retired amateurs, who represent a larger population, is uncertain. The present meta-analysis integrates new results from individual-participant analyses of a cohort study of former amateur contact sports participants into a systematic review of existing studies of retired professionals and amateurs. Methods The cohort study comprised 2005 male retired amateur athletes who had competed internationally for Finland (1920–1965) and a general population comparison group of 1386 …