Search results for "PID"

showing 10 items of 11585 documents

Lipid Binding Controls Dimerization of the Coat Protein p24 Transmembrane Helix

2019

Abstract Coat protein (COP) I and COP II complexes are involved in the transport of proteins between the endoplasmic reticulum and the Golgi apparatus in eukaryotic cells. The formation of COP I/II complexes at membrane surfaces is an early step in vesicle formation and is mastered by p24, a type I transmembrane protein. Oligomerization of p24 monomers was suggested to be mediated and/or stabilized via interactions within the transmembrane domain, and the p24 transmembrane helix appears to selectively bind a single sphingomyelin C18:0 molecule. Furthermore, a potential cholesterol-binding sequence has also been predicted in the p24 transmembrane domain. Thus, sphingomyelin and/or cholestero…

virusesLipid BilayersBiophysicsProtein Structure Secondary03 medical and health sciencessymbols.namesake0302 clinical medicineimmune system diseasesAmino Acid Sequence030304 developmental biology0303 health sciencesChemistryEndoplasmic reticulumVesicleCholesterol bindingvirus diseasesArticlesCOPIGolgi apparatusLipidsTransmembrane proteinSphingomyelinsTransmembrane domainCholesterolsymbolsBiophysicsCapsid Proteinslipids (amino acids peptides and proteins)SphingomyelinDimerization030217 neurology & neurosurgeryBiophysical Journal
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Conception en technologie CMOS d'un Système de Vision dédié à l'Imagerie Rapide et aux Traitements d'Images

2008

Our work presented in this thesis focuses on the design, testing and implementation of monolithics CMOS image smart sensors : The principle, performance and limitations. The hardware implementation of a vision smart system is the central link. HISIC is High Speed Image Capture with processing at pixel level. An experimental platform for instrumentation and evaluation of retina operators was conducted during this thesis. After a state of the smart sensors and CMOS retinas, the second part is dedicated to the study and design of the pixel image sensor HISIC. Two circuits were realized in CMOS technology. The first identied a new type of photo-detector, and the second, to create a prototype em…

vision artificielleimagerie rapiderecongurabilityprogrammability[SPI.NANO] Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronicsparallélisme massifspeed imagingSystème embarquéartificial vision.image processing on focal planerecongurabilitéprogrammabilitéstandard CMOS technology[ SPI.NANO ] Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/MicroelectronicsEmbedded systemtraitements d'images sur plan focalmassive paralleltechnologie standard CMOS
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Lipid-related thiamine deficiency cause mortality of river lampreys (Lampetra fluviatilis) during pre-spawning fasting

2023

Publisher Copyright: © 2023 The Authors River lampreys (Lampetra fluviatilis) were caught in the fall 2014 on entering the River Perhonjoki for spawning and kept at a hatchery until spawning in late spring 2015 to produce larvae for compensatory stockings. Since the lampreys died massively from early February onwards, they were investigated in March and May to clarify the cause of the deaths. The symptoms in lampreys resembled those of lipid-related thiamine (vitamin B1) deficiency of salmonines, called the M74 syndrome in the Baltic Sea area. Because the lipid content of lampreys was known to be high, thiamine concentrations were analyzed in the liver and ovulated unfertilized eggs, and th…

vitamin B1vaelluskalatthiamine deficiencyEcologyBody lipidnahkiainen1184 Genetics developmental biology physiologylipiditAquatic SciencepuutostilatLampetra fluviatiliskuolemansyytM74 syndromebody lipidpre-spawning fastingThiamine deficiencylamprey Lampetra fluviatilisAnimal Science and ZoologytiamiiniLamprey Lampetra fluviatilisPre-spawning fastingEcology Evolution Behavior and SystematicsVitamin B1
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Kokemuksia vapaaehtoisesta lapsettomuudesta ja sterilisaatiosta -kirjoitusaineisto 2017

2022

Aineisto koostuu vapaaehtoista lapsettomuutta ja sterilisaatiota käsittelevistä kirjoituksista. Kirjoituspyyntöön saivat vastata kaikki itsensä kohderyhmään kuuluvaksi määrittelevät henkilöt. Aineisto on kerätty alun perin pro gradu -tutkielmaan vuonna 2017. Kirjoituskutsun avulla pyrittiin selvittämään mm. sitä, miten päätös vapaaehtoisesta lapsettomuudesta on syntynyt ja millaisia ajatuksia sterilisaatio vastaajissa herättää. Tarkoitus oli saada tietoa myös siitä, miksi sterilisaatioon hakeudutaan ja millaisia vaikutuksia toimenpiteellä on ollut vapaaehtoisesti lapsettomien ihmisten elämään. Haluttiin myös tietää, millaisena tilanteen näkevät ne, jotka toivoisivat toimenpidettä, mutta eiv…

voluntary childlessnesssterilisation (medical procedures)perhesuunnittelumedicine (science)family planningmedical anthropologycontraceptive methodslääketiedevapaaehtoinen lapsettomuusehkäisymenetelmätsterilointi (lääketieteellinen toimenpide)lääketieteellinen antropologia
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Mielipiteen vuorovaikutuksellinen rakentaminen syntyperäisen ja ei-syntyperäisen suomenpuhujan keskustelussa.

1998

vuorovaikutuskielentutkimuksen alueetkeskusteluntutkimustoisen kielen oppiminenpragmatiikkakielenopetuskannanototsuomi toisena ja vieraana kielenäsuomi vieraana kielenämielipidekeskustelutekstilingvistiikka ja pragmatiikkainterpersonaaliset suhteetmielipiteen rakentaminen
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Complex plant quality—microbiota–population interactions modulate the response of a specialist herbivore to the defence of its host plant

2022

Many specialist herbivores have evolved strategies to cope with plant defences, with gut microbiota potentially participating to such adaptations. In this study, we assessed whether the history of plant use (population origin) and microbiota may interact with plant defence adaptation. We tested whether microbiota enhance the performance of Melitaea cinxia larvae on their host plant, Plantago lanceolata and increase their ability to cope the defensive compounds, iridoid glycosides (IGs). The gut microbiota were significantly affected by both larval population origin and host plant IG level. Contrary to our prediction, impoverishing the microbiota with antibiotic treatment did not reduce larv…

vuorovaikutusplant defencesuolistomikrobistoDIET QUALITYperhosetherbivoretoukatplant defenseglykosiditkasvitmicrobiotapuolustusmekanismit (biologia)ravintoketjutEcology Evolution Behavior and Systematicstrophic interactionsisäntäkasvitGUT MICROBIOTAMIDGUTIRIDOID GLYCOSIDE SEQUESTRATIONMELITAEA-CINXIApopulaatioekologiaLepidopteraGENERALISTCHEMICAL DEFENSEkasvinsyöjätBACTERIA1181 Ecology evolutionary biologySURVIVALmikro-organismitLANCEOLATA
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La metodica wastewater based epidemiology come proxy di quantificazione del consumo di sostanze stupefacenti nella popolazione: l’esperienza della ci…

2016

INTRODUZIONE Le istituzioni europee e la comunità scientifica hanno, recentemente, definito un nuovo modello di sorveglianza attiva della potenziale diffusione delle droghe nella collettività, la Wastewater Based Epidemiology (WBE), attraverso la ricerca analitica delle molecole e dei loro metaboliti nelle acque reflue cittadine. Lo scopo di questo lavoro è stato la valutazione di una preliminare applicazione di METODIca WBE nella città di Palermo, poco studiata in precedenti analisi a livello nazionale e internazionale. METODI Sono stati prelevati 28 campioni (2 litri cad) di refluo medio delle 24 ore in ingresso ai due depuratori di Palermo (WP1=45.000 ab. eq.; WP2=330.000 ab. eq.) in un …

wastewater based epidemiology acque reflue sostanze stupefacentiSettore MED/42 - Igiene Generale E Applicata
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Development of an immunochromatographic assay based on carbon nanoparticles for the determination of the phytoregulator forchlorfenuron

2013

Rapid analytical methods enabling the determination of diverse targets are essential in a number of research areas, from clinical diagnostics to feed and food quality and safety. Herein, the development of a quantitative immunochromatographic assay for the detection of the synthetic phytoregulator forchlorfenuron (CPPU) is described. The competitive lateral flow immunoassay (LFIA) was based on the immobilization onto a nitrocellulose membrane of an ovalbumin-CPPU conjugate (test line) and on the use of an immunodetection ligand consisting of carbon nanoparticles labeled with an anti-CPPU monoclonal antibody through interaction with a secondary antibody. The presence of CPPU in horticultural…

water samplesCarbon nanoparticlesAnalyteImmunoreactive stripsPyridinesCarbon NanoparticlesBiomedical EngineeringBiophysicsEnzyme-Linked Immunosorbent AssayCPPUBiosensing Techniquesantibody-based immunoassayForchlorfenuronbiosensorHigh-performance liquid chromatographychemistry.chemical_compoundElectrochemistryImmunoassayDetection limitvalidationChromatographyChemistrystrip testPhenylurea Compoundslateral flow immunoassayAntibodies Monoclonalcomputer image-analysisGeneral MedicineCarbonHaptendipstick assayBBP Bioconversionrapid detectionImmunosensingNanoparticlessensitive detectionBiosensorNitrocelluloseBiotechnologyConjugate
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The AQP2 mutation V71M causesnephrogenic diabetes insipidus in humans but does not impair the function of a bacterial homolog

2015

Graphical abstract

wt wild-typeGpA glycophorin AHM half-membrane-spanningurogenital systemQH301-705.5AquaporinNephrogenic diabetes insipidusAQP ER endoplasmic reticulumGlpF glycerol facilitatorActivityProtein oligomerizationResearch articleNDI nephrogenic diabetes insipidusAVP arginine vasopressinGlpF500 Natural sciences and mathematicsAQP aquaporin500 NaturwissenschaftenBiology (General)AVPR2 V2 receptorComputingMethodologies_COMPUTERGRAPHICSTM transmembraneFEBS Open Bio
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"Ilman mielipiteitä muutoksia ei tapahdu!" : yleisö, esisopimukset ja retoriset keinot sukupuolineutraalia avioliittoa käsittelevissä mielipidekirjoi…

2012

Tutkimuksessa tarkastellaan sukupuolineutraalia avioliittoa käsitteleviä mielipidekirjoituksia. Tavoitteena on selvittää, miten kirjoittajat suhtautuvat sukupuolineutraaliin avioliittoon tutkimalla etenkin näissä kirjoituksissa käytettyä retoriikkaa, mutta myös niiden yleisösuhdetta ja esisopimuksia. Tutkimuskysymykseni ovat: Millaisia yleisöjä kirjoittajien teksteissä on? Millaisia esisopimuksia teksteissä on? Miten kirjoittajat pyrkivät vaikuttamaan lukijoihin? Millaisia retorisia keinoja he käyttävät? Millaisia arvoja ja asenteita teksteissä ilmenee / rakentuu? Aineistona on 38 sukupuolineutraaliin avioliittoon liittyvää mielipidekirjoitusta, jotka ilmestyivät vuoden 2010 Homoillan aikaa…

yleisömielipidekirjoituksetrekisteröity parisuhdeavioliittoretoriikkasukupuolineutraali avioliittokirkkoesisopimuksetseksuaaliset vähemmistöt
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