Search results for "PIDE"
showing 10 items of 6055 documents
Mutations in p53 Gene Exons in a Sample from the South of Spain in Oral Cancer
2021
[Background+ Cancer is a genetic disease caused by mutations in DNA and epigenetic alterations that control gene expression. The majority of epidermoid carcinomas develop within the fields of epithelial genetic alterations. The mechanisms underlying tumorigenesis of epidermoid carcinoma are as yet unknown; therefore, precise identification of the risk factors is needed.
Análisis epidemiológico, clínico y microbiológico del brote de candidiasis invasora por Candida auris en el Hospital Universitario y Politécnico La Fe
2020
INTRODUCCIÓN: Candida auris es una levadura patógena responsable de brotes hospitalarios, especialmente en las unidades de cuidados intensivos (UCI). C. auris tiene características que la hacen muy diferente de otras especies de Candida: i) Los métodos comerciales basados en técnicas fenotípicas no la identifican, ii) ha surgido de forma independiente y simultánea en tres continentes; iii) presenta una elevada resistencia a los antifúngicos, pudiendo llegar a ser multirresistente; y iv) persiste durante semanas en el entorno hospitalario y además puede colonizar indefinidamente a los pacientes favoreciendo la trasmisión de paciente a paciente, principalmente en pacientes en estado crítico. …
Oral paracoccidioidomycosis:a retrospective study of 95 cases from a single center and literature review
2023
The ecoepidemiological panorama of paracoccidioidomycosis (PCM) is dynamic and still ongoing in Brazil. In particular, data about the oral lesions of PCM are barely explored. The aim of this study was to report the clinicopathological features of individuals diagnosed with oral PCM lesions at an oral and maxillofacial pathology service in Rio de Janeiro, Brazil, in the light of a literature review. A retrospective study was conducted on oral biopsies obtained from 1958 to 2021. Additionally, electronic searches were conducted in PubMed, Embase, Scopus, Web of Science, Latin American and Caribbean Center on Health Sciences Information, and Brazilian Library of Dentistry to gather information…
Appendicular fracture epidemiology of children and adolescents: a 10-year case review in Western Australia (2005 to 2015)
2018
Fracture incidence data of Australian children and adolescents have not been reported in the literature. A 10-year case review of fracture presentations in Western Australia is provided. Between 2005 and 2015, fracture incidence increased relative to population growth. This is concerning, and interventions are required to reverse this trend. Purpose Fracture incidence in 0–16-year-olds is high and varies between countries. Boys have a 1.5:1 ratio of fracture incidence compared to girls. There are no specific data for Australia. Western Australia is a state with unique geography and population distribution having only a single tertiary paediatric hospital (Princess Margaret Hospital, PMH, in…
Interaction between regulatory framework for vaccination and restrictions on freedom of movement
2021
COVID-19 infekcijas slimības uzliesmojums ir būtiski palielinājis tiesību jautājumu aktualitāti, kas saistīti ar personu vakcināciju un citiem epidemioloģiskās drošības pasākumiem, jo tie var radīt nozīmīgus cilvēku pamattiesību aizskārumus. Bakalaura darbā autors, aplūkojot Latvijas un starptautisko tiesību normas, praksi un judikatūru, pēta, kādā veidā obligātās vakcinācijas regulējums mijiedarbojas ar personu brīvas pārvietošanās tiesībām un to potenciālajiem ierobežojumiem. Padziļinātas analīzes rezultātā darbā tiek piedāvāts vispusīgs ieskats samērīguma nepieciešamībā, īstenojot pasākumus, kas vērsti uz sabiedrības veselības un drošības aizsardzību, kā arī tiek konstatēts, ka vakcināci…
La pandemia de COVID-19 a la luz de la historia de la medicina
2020
La actual pandemia producida por el nuevo coronavirus SARS-CoV-2 ha originado, desde que a finales de 2019 surgiera en la ciudad china de Wuhan, el contagio de más de dos millones y medio de personas en 185 países de todo el mundo, con una cifra de fallecidos que superaba los 180.000 a finales de abril. ¿Se pueden encontrar similitudes con otras epidemias del pasado en cuanto a la manera de originarse, la forma de expandirse, el pánico desatado en la población, las medidas tomadas por las autoridades para frenar el contagio y las repercusiones médicas, demográficas y económicas? La reflexión históricomédica sobre la evolución de las infecciones puede darnos una perspectiva amplia que ayude …
Panic disorder, anxiety, and cardiovascular diseases
2014
Different data indicate that psychological and/or emotional disorders may play an important role in the natural history of heart diseases. Although the major evidence is that related to depression, epidemiological data would indicate that anxiety and panic disorders are highly represented in cardiac patient, thus influencing mortality and morbidity. The diagnosis of panic disorder in patients with chest pain is crucial to a correct therapeutic approach, as well as to reduce the risks and costs of inappropriate treatments. Anxiety and panic may accelerate different direct and indirect processes involved in the pathogenesis of cardiovascular diseases: lifestyle risk factors, arterial hyperten…
Research data of article: "Sympatric Ixodes-tick species: pattern of distribution and pathogen transmission within wild rodent populations"
2018
Longitudinal monitoring of bank voles as well as their ticks and tick-borne pathogens in Central Finland, carried out in 2012.
Bloodstream Infection Incidence of Different Central Venous Catheters in Neonates: A Descriptive Cohort Study
2017
Central venous catheters (CVCs) in neonates are associated with a risk of central line-associated bloodstream infections (CLABSI). Most reports on the incidence of CLABSI in neonates focus on umbilical venous catheters (UVCs) and peripherally inserted central catheters (PICCs). We evaluated the incidence and risk factors for CLABSI in a cohort of neonates with femoral venous catheters (FVCs), UVCs, and PICCs, with a gestational age ≥34 weeks born between January 1, 2006 and June 30, 2013. We included 2,986 neonates with a total of 656 catheters. The CLABSI incidence rate varied from 12.3 per 1,000 catheter-days in FVCs to 10.6 per 1,000 catheter-days in UVCs and 5.3 per 1,000 catheter-days …
Peroxisome Proliferator-Activated Receptors and Atherosclerosis
2011
The peroxisome proliferator-activated receptors (PPARs) represent the family of 3 nuclear receptor isoforms-PPARα, -γ, and -δ/β, which are encoded by different genes. As lipid sensors, they are primarily involved in regulation of lipid metabolism and subsequently in inflammation and atherosclerosis. Atherosclerosis considers accumulation of the cells and extracellular matrix in the vessel wall leading to the formation of atherosclerotic plaque, atherothrombosis, and other vascular complications. Besides existence of natural ligands for PPARs, their more potent synthetic ligands are fibrates and thiazolidindiones. Future investigations should now focus on the mechanisms of PPARs activation, …