Search results for "PIO"

Corynebacterium parvum (Propionibacterium acnes): an inducer of tumor necrosis factor-alpha in human peripheral blood mononuclear cells and monocytes…

1990

The present study investigates the potential capacity of the immunostimulant Corynebacterium parvum (C.p.) to induce tumor necrosis factor-alpha (TNF-alpha) in human peripheral blood mononuclear cells (PBMC) and blood monocytes (BMo) in vitro. Both at the mRNA and protein level, stimulation of PBMC and BMo upon C.p. induces TNF-alpha. Compared to the hitherto used TNF-alpha inducers in vitro such as Sendai virus, phytohemagglutinin or lipopolysaccharide the C.p. stimulus displayed a threefold stronger induction of TNF-alpha production (p less than 0.001). Using C.p. as an inducer it was possible to demonstrate that TNF-alpha production is regulated by prostaglandin E2; preincubation of the …

La dicotomía interior-litoral en la provincia de Castellón y sus consecuencias demográficas

1979

Transcatheter arterial chemoembolization therapy for patients with hepatocellular carcinoma: a case-controlled study.

2005

Background & Aims: Transcatheter arterial chemoembolization (TACE) currently is used as a palliative treatment for patients with unresectable hepatocellular carcinoma (HCC), but its efficacy still is debated. Our aim was to assess the impact of TACE on patient survival and to identify prognostic factors for survival. Methods: Fifty-six cirrhotic patients with unresectable HCC undergoing at least :1 course of TACE were matched 1:1. for sex, age (in 5-year periods), parameters of Child-Pugh score, Okuda stage, and tumor type with a control group who had received only supportive care. Results: The 2 groups were comparable for cause of cirrhosis, alpha-fetoprotein serum levels, and Cancer of th…

Long-lasting rewarding effects of morphine induced by drug primings.

2005

To evaluate the persistence of the rewarding effects of morphine, the acquisition, maintenance, extinction and reinstatement of a conditioned place preference (CPP) was assessed in OF1 mice. In Experiment 1, the persistence of morphine-induced CPP was evaluated weekly. Mice showed CPP after four sessions of conditioning with 5, 10, 20 and 40 mg/kg of morphine, which lasted 0, 1, 2 and 4 weeks, respectively. In Experiment 2, after four sessions of conditioning with 40 mg/kg of morphine, the effects of four schedules of extinction differing in the time interval (2, 4, 6 or 8 weeks) between sessions were evaluated. CPP was no longer evident after 8 weeks for the groups examined each 2 or 8 wee…

Tempi del racconto e racconto del tempo in Piove all’insù

2022

Times of narration and narration of the time in Piove all’insù · The article hosts an analysis of the time categories in Luca Rastello’s novel Piove all’insù (2006). In the first section there is a survey of the verb tenses used in the narration of the past by the main character (who is also the narrator). These tenses contribute to make the two periods of time (the 1970s and the 2000s) constantly overlap each other. A second section is dedicated to the influence of the peculiar timeframes on the anti-utopian and pseudo-science-fictional gradient of the novel. A third section faces the issue of the father/son confrontation in Piove all’insù. All these elements help to define a notion of lit…

Quando gli oracoli passano di moda: L’episodio di Appio e Femonoe nel quinto libro della Pharsalia di Lucano

2016

Analisi dell'episodio del quinto libro della Pharsalia avente per protagonista la profetessa Femonoe

Multixenobiotic resistance efflux activity in Daphnia magna and Lumbriculus variegatus

2014

Multixenobiotic resistance is a phenomenon in which ATP-binding cassette (ABC) family proteins transfer harmful compounds out of cells. Daphnia magna and Lumbriculus variegatus are model species in aquatic ecotoxicology, but the presence and activity of ABC proteins have not been well described in these species. The aim of this work was to study the presence, activity, and inhibition of ABC transport proteins in D. magna and L. variegatus. The presence of abcb1 and abcc transcripts in 8-9-day-old D. magna was investigated by qRT-PCR. The activity of MXR in D. magna and L. variegatus was explored by influx of the fluorescent ABC protein substrates rhodamine B and calcein-AM, with and without…

Kalmbergin kartasto R III : List 7

1855

Kalmbergin kartasto R IV : List 7

1855

Prospettive dialettiche intorno alla definizione del fenomeno mafioso

2023

Il fenomeno mafioso non nasce certo con l’istituzione della legge n. 646, del 13 settembre 1982, fortemente voluta da Pio La Torre e approvata, non già dopo la sua morte (il 30 aprile del 1982) ma solo all’indomani della strage di via Carini, dove persero la vita il prefetto di Palermo Carlo Alberto Dalla Chiesa, la giovane moglie Emanuela Setti Carraro e l’agente di scorta Domenico Russo. Ma in quella data viene dato un nome e un riconoscimento giuridico – suggellato in uno specifico articolo del codice penale, il 416bis – a un fenomeno criminale risalente nel tempo. Su queste diverse prospettive, sulla tardività del parlamento nel legiferare in questa materia e sulle battaglie dialettiche…