Search results for "PIP"

Pippin protein expression changes during cell differentiation

2008

PIPPin is a CSD-containing protein with the ability to interact both with mRNAs encoding histone variants and chromatin. A major fraction of chromatin-bound PIPPin is sumoylated and sumoylation seems to be controlled by thyroid hormones, both in vivo and in vitro. We studied its expression in different tissues and cell lines and even in tumor cells and found that, even if more expressed in the brain respect to other tissues of the adult rat, it is also expressed in brain tumors and in cell lines as different as kidney NRK cells and PC12. The expression of the protein is strongly increased by treatments that induce differentiation, such as treatment of PC12 with NGF. We also found an increas…

PIPPIN SUMOYLATION IS CONTROLLED BY THYROID HORMONES

2006

Pittura del XIX e del XX secolo nel segno del collezionismo siciliano

2020

Il volume offre una ricognizione sul collezionismo in Sicilia e prende in esame, per la prima volta nella sua interezza, una collezione privata proponendo la riscoperta di opere di autori rappresentativi della cultura figurativa italiana del XIX e del XX secolo, tra cui Michele Catti, Ettore De Maria Bergler, Onofrio Tomaselli, Pippo Rizzo, Alfonso Amorelli e Pina Calì. La collezione privilegia la pittura dell’isola ma include anche il pittore non siciliano Giuseppe Amisani e la coppia di bronzi di Antonio Ugo e trova nelle opere "Costumi" di Salvatore Lo Forte del 1839 e "Sogno del carabiniere" di Pippo Rizzo degli anni ’50 i propri limiti cronologici. Questa raccolta privata, per lo più i…

A distributed genetic algorithm for restoration of vertical line scratches

2008

This paper reports a distributed algorithm for the restoration of still frames corrupted by vertical line scratches. The restoration is here approached as an optimisation problem, and is solved using an ad-hoc Genetic Algorithm. The distributed algorithm is designed following a pipeline logical structure. The front end is a network of standard workstations with heterogeneous operating systems. The quality of image is appreciable and the computational time is quite low with respect the sequential version.

Operators on Partial Inner Product Spaces: Towards a Spectral Analysis

2014

Given a LHS (Lattice of Hilbert spaces) $V_J$ and a symmetric operator $A$ in $V_J$, in the sense of partial inner product spaces, we define a generalized resolvent for $A$ and study the corresponding spectral properties. In particular, we examine, with help of the KLMN theorem, the question of generalized eigenvalues associated to points of the continuous (Hilbertian) spectrum. We give some examples, including so-called frame multipliers.

Pathway-specificity in N-methyl-d-aspartate receptor-mediated synaptic inputs onto subplate neurons

2007

The subplate plays an important role in forming neuronal connections during early cortical development. We characterized by the use of whole-cell and cell-attached patch-clamp recordings in coronal brain slices from newborn mice (postnatal day [P] 0-3) the functional properties of two major pathways onto subplate neurons (SPn), the thalamocortical and the intra-subplate synaptic input. The two afferent pathways were stimulated extracellularly with bipolar electrodes placed in the thalamus and the subplate, respectively. Synaptically evoked and pharmacologically isolated N-methyl-d-aspartate receptor (NMDAR) -mediated responses with an onset latency of approximately 6 ms could be reliably re…

Dermatofibrosarcoma protuberans: a comprehensive review and update on diagnosis and management

2013

Dermatofibrosarcoma protuberans (DFSP) is a rare superficial tumor characterized by high rates of local recurrence and low risk of metastasis. DFSP occurs most commonly on the trunk and proximal extremities, affects all races, and often develops between the second and fifth decade of life. The tumor grows slowly, typically over years. Histologically, several variants of DFSP have been described and should be well characterized to avoid misdiagnosis with other tumors. These include pigmented (Bednar tumor), myxoid, myoid, granular cell, sclerotic, atrophic DFSP, giant cell fibroblastoma, and DFSP with fibrosarcomatous areas. Of all these variants, only the DFSP with fibrosarcomatous areas is…

Modeling of Offshore Crane and Marine Craft in Wave Motion

2020

Safe handling of heavy payloads in an offshore environment requires careful planning and depends on the interaction between a crane and a vessel. This paper investigates the coupled dynamics between a multipurpose crane with payload, and an offshore carrying vessel. A classical multi-body model is derived using holonomic constraints and Newton-Euler kinetics. The resulting index-3 system of differential-algebraic equation (DAE) is transformed into an index-1 system and solved using commonly used numerical ode solvers. Numerical simulations are carried out to show that the proposed models behave in a physically realistic manner. © 2020 IEEE. Personal use of this material is permitted. Permis…

Lignocellulosic biomass production and persistence of perennial grass species grown in mediterranean marginal lands

2021

© 2021 by the authors.

Pressurized intraperitoneal aerosol chemotherapy with cisplatin and doxorubicin or oxaliplatin for peritoneal metastasis from pancreatic adenocarcino…

2020

Background: Systemic chemotherapy for pancreatic adenocarcinoma (PDAC) and cholangiocarcinoma (CC) with peritoneal metastases (PM) is affected by several pharmacological shortcomings and low clinical efficacy. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is expected to maximize exposure of peritoneal nodules to antiblastic agents. This study aims to evaluate safety and efficacy of PIPAC for PM of PDAC and CC origin. Methods: This is a retrospective analysis of consecutive PDAC and CC cases with PM treated with PIPAC at two European referral centers for peritoneal disease. We prospectively recorded from August 2016 to May 2019 demographic, clinical, surgical, and oncological data…