Search results for "PIV"
showing 10 items of 376 documents
Modeling of Water Distribution under Center Pivot Irrigation Technique
2021
AbstractAiming to quantify the impacts of the center pivot irrigation technique on soil moisture dynamics and to improve irrigation crop water needs, a mathematical model was developed to estimate ...
Evaluation of enantioselective binding of basic drugs to plasma by ACE.
2007
The present paper deals with the evaluation of the stereoselective binding of antihistamines (brompheniramine, chlorpheniramine, hydroxyzine, orphenadrine and phenindamine), phenothiazines (promethazine and trimeprazine) and a local anesthetic (bupivacaine) to human plasma proteins. Since all of them are drugs highly bound to proteins, a methodology to determine the bound fraction of each drug enantiomer was proposed. This methodology includes the incubation of samples containing plasma and racemic drug, ultrafiltration of the mixture and the chiral separation of enantiomers in the bound drug fraction using affinity EKC (AEKC)-partial filling technique and HSA as chiral selector. The result…
The efficacy and safety of unfixed and fixed combinations of latanoprost and other antiglaucoma medications.
2002
Adjunctive therapy for the management of glaucoma is commonly used. Unfixed combinations of the prostaglandin analog latanoprost and other glaucoma medications have been demonstrated to effectively lower intraocular pressure (IOP). The range of reported additional reductions in IOP compared to a monotherapy baseline are as follows: latanoprost-timolol (13-37%), latanoprost-pilocarpine 2% (7-14%), latanoprost and carbonic anhydrase inhibitors (15-24.1%), and latanoprost and dipivefrin (15-28%). There is a fixed combination of latanoprost (0.005%) and timolol (0.5%) that has been investigated in Phase III trials in Europe and the United States. In these trials, it was noted that the efficacy …
Improvement of Inventory Control under Parametric Uncertainty and Constraints
2011
The aim of the present paper is to show how the statistical inference equivalence principle (SIEP), the idea of which belongs to the authors, may be employed in the particular case of finding the effective statistical decisions for the multi-product inventory problems with constraints. To our knowledge, no analytical or efficient numerical method for finding the optimal policies under parametric uncertainty for the multi-product inventory problems with constraints has been reported in the literature. Using the (equivalent) predictive distributions, this paper represents an extension of analytical results obtained for unconstrained optimization under parametric uncertainty to the case of con…
Hydraulic Design of the Center-Pivot Irrigation System for Gradually Decreasing Sprinkler Spacing
2021
Design strategies that enhance modern irrigation practices, reduce energy consumption, and improve water use efficiency and crop yields are fundamental for sustainability. Although microirrigation is currently a widely applied method, center-pivot irrigation systems have become very popular on large farms, thanks to their automation, wide-coverage, and reliability. Different design procedures have been proposed, even though some aspects have not been solved yet. This paper presents a simple design procedure for center-pivot systems using a gradually decreasing sprinkler spacing along with a pivot lateral, which makes it possible to set favorable and uniformly distributed water application r…
Etanola tvaiku iedarbības novērtējums uz nodarbinātajiem uzņēmumā SIA “Jaunpagasts Plus”
2017
Kvalifikācijas darba tēma ir “Etanola tvaiku iedarbība uz nodarbinātajiem novērtējums uzņēmumā SIA “Jaunpagasts Pluss”, darba autore Ieva Straujā, darba vadītāja pasniedzēja Mg.da., ing. Daina Pužule. Šī tēma ir ļoti būtiska, jo cilvēki šajā uzņēmumā ik dienā saskaras ar ķīmiskām vielām, tai skaitā etanolu, kurš ir visas ražošanas būtība. Bez etanola netiktu saražota pārējā uzņēmuma produkcija. Iespējams, pēc mana pētījuma izstrādes, darbinieki sāks vairāk ievērot darba drošību savā darbavietā. Darba mērķis: izpētīt, analizēt etanola bīstamību uz cilvēka veselību. Darba uzdevumi: •Izpētīt etanola iedarbību uz nodarbināto veselību un drošību; •Apkopot informāciju par avārijas iespējamību uzņ…
Darba aizsardzības sistēmas un darbības analīze pašvaldības aģentūrā “SAN-TEX"
2017
Temats ir aktuāls, jo Balvu novada pašvaldības aģentūra „SAN-TEX” ir vidēji liela organizācija ar vairākām darbības nozarēm, kur ir svarīgi ievērot darba drošību un veselību. Darba mērķis ir teorētiski pamatot un empīriski pārbaudīt darba aizsardzības sistēmas darbību Balvu novada pašvaldības aģentūrā „SAN-TEX”. Pētījuma teorētiskajā daļā aprakstīta darba aizsardzības sistēmas struktūra organizācijā, tās izveides un darbības nosacījumi. Pētījumā atklāta sistēmas darbība pašvaldības aģentūrā „SAN-TEX”. Atslēgas vārdi: DARBA AIZSARDZĪBAS SISTĒMA, DARBA VIETA, RISKA FAKTORI, UZRAUDZĪBA, KONTROLE, LĪDZDALĪBA, APMĀCĪBA, UZTICĪBAS PERSONA. Kvalifikācijas darba izstrādes laikā izmantoti 18 avoti, …
Bupivakaīna hidrohlorīda un lidokaīna hidrohlorīda degradācija
2015
Bupivakaīna hidrohlorīda un lidokaīna hidrohlorīda degradācija. Bakalaura darbs. Rozenvalds R., darba vadītājs Dr.chem. Nakurte I. un Mag. ķīm Kuprevičs K., 37 lapas, 5 attēli, 10 tabulas, 46 literatūras avoti, 19 attēli pielikumā. Latviešu valodā. BUPIVAKAĪNS, LIDOKAĪNS, DEGRADĀCIJA, PIEMAISĪJUMI, GĀZU HROMATOGRĀFIJA, AUGSTI EFEKTĪVĀ ŠĶIDRUMA HROMATOGRĀFIJA Literatūras aprakstā ir apkopota informācija par bupivakaīna hidrohlorīdu un lidokaīna hidrohlorīdu, šo preparātu īpašībām, pielietojumu farmācijā un zināmajiem piemaisījumiem. Literatūras apskatā veikts vispārējs ieskats aktīvo vielu stabilitātē un piemaisījumu noteikšanas analītisko metožu validācijā. Darba eksperimentālajā daļā ir ve…
Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells
2020
ObjectiveLiver fibrosis constitutes a major health problem worldwide due to its rapidly increasing prevalence and the lack of specific and effective treatments. Growing evidence suggests that signalling through cytokine-activated Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathways regulates liver fibrosis and regeneration. Rilpivirine (RPV) is a widely used anti-HIV drug not reported to produce hepatotoxicity. We aimed to describe the potential hepatoprotective effects of RPV in different models of chronic liver injury, focusing on JAK-STAT signalling regulation.DesignThe effects of RPV on hepatic steatosis, inflammation and fibrogenesis were studied in a nut…
Volume and effectiveness assessment of articain 4% versus mepivacaine 2% used in third molar surgery : randomized, double-blind, split-mouth controll…
2020
Made available in DSpace on 2021-06-25T11:06:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 Background: The different indications for extraction of the lower third molars, require resources to manage pain and discomfort, such as, for example, adequate anesthetic techniques, and the type of anesthetic used can in-fluence the management of pain in tooth extractions. Few studies in the literature compare the anesthetics 4% articaine hydrochloride and 2% mepivacaine hydrochloride showing evidence that both allow for successful pain management. This study sought to compare the volume, efficacy and safety of these two anesthetic drugs, both associated with epinephrine at a ratio …