Search results for "PLASMA"

Plasma concentration following oral and intramuscular atropine in children and their clinical effects.

1997

In a paediatric population, we compared i.m. v oral atropine premedication to a control group without atropine and determined atropine plasma concentrations (APC). Forty-five children were randomly assigned to one of three groups. Group I received atropine, 20 micrograms.kg-1 i.m., 15 min prior to induction. Group II received atropine, 30 micrograms.kg-1 orally, group III received no atropine. APC (expressed as percent of muscarine-2 receptor subtype occupancy), heart rate, rectal temperature, and salivation were determined before atropine, and 15, 25, 45, 60, 90, 120 (no APC), and 150 min following atropine. Only 10-20% of the M2-cholinoceptors were occupied after oral atropine with a peak…

Dissipative lattice model with exact traveling discrete kink-soliton solutions: Discrete breather generation and reaction diffusion regime

1999

International audience; We introduce a nonlinear Klein-Gordon lattice model with specific double-well on-site potential, additional constant external force and dissipation terms, which admits exact discrete kink or traveling wave fronts solutions. In the nondissipative or conservative regime, our numerical simulations show that narrow kinks can propagate freely, and reveal that static or moving discrete breathers, with a finite but long lifetime, can emerge from kink-antikink collisions. In the general dissipative regime, the lifetime of these breathers depends on the importance of the dissipative effects. In the overdamped or diffusive regime, the general equation of motion reduces to a di…

Recent progress in developing a feasible and integrated conceptual design of the WCLL BB in EUROfusion project

2019

The water-cooled lithium-lead breeding blanket is in the pre-conceptual design phase. It is a candidate option for European DEMO nuclear fusion reactor. This breeding blanket concept relies on the liquid lithium-lead as breeder-multiplier, pressurized water as coolant and EUROFER as structural material. Current design is based on DEMO 2017 specifications. Two separate water systems are in charge of cooling the first wall and the breeding zone: thermo-dynamic cycle is 295–328 °C at 15.5 MPa. The breeder enters and exits from the breeding zone at 330 °C. Cornerstones of the design are the single module segment approach and the water manifold between the breeding blanket box and the back suppo…

Forensic investigation of brick stones using instrumental neutron activation analysis (INAA), laser ablation-inductively coupled plasma-mass spectrom…

2009

Abstract Brick stones collected from different production facilities were studied for their elemental compositions under forensic aspects using laser ablation–inductively coupled plasma–mass spectrometry (LA–ICP–MS), instrumental neutron activation analysis (INAA) and X-ray fluorescence analysis (XRF). The aim of these examinations was to assess the potential of these methods in forensic comparison analyses of brick stones. The accuracy of the analysis methods was evaluated using NIST standard reference materials (679, 98b and 97b). In order to compare the stones to each other, multivariate data analysis was used. The evaluation of the INAA results (based on the concentrations of V, Na, K, …

Direct determination of halogens in powdered geological and environmental samples using isotope dilution laser ablation ICP-MS

2005

Abstract Laser ablation inductively coupled plasma isotope dilution mass spectrometry (LA-ICP-IDMS) with a special laser ablation system for bulk analyses (LINA-Spark™-Atomiser) was applied for direct determinations of chlorine, bromine, and iodine in rock and sediment samples. Special attention was focused on possible inter-halogen fractionations and analyte/spike isotope fractionations by using LA-ICP-MS and LA-ICP-IDMS, respectively. A variation of Br/Cl and I/Cl element intensity ratios by a factor of 1.3–3 was observed when changing the nebulizer gas flow rate in the range of 0.84–1.0 L min−1 and the laser power density in the range of 2–10 GW cm−2, respectively. When using an internal…

Laser-induced plasma spectroscopy in near vacuum ultraviolet using ordinary spectrograph and ICCD

2002

An experimental setup to measure laser-induced plasma emission spectra with an ordinary Czerny-Turner spectrograph and intensified charge-coupled device in the near vacuum ultraviolet down to 130 nm is described. Spectra of bromine, chlorine and iodine were recorded to demonstrate the performance of the setup.

Determination of bupivacaine in human plasma by high-performance liquid chromatography.

1984

Plasma calprotectin levels in patients suffering from acute pancreatitis

2006

Calprotectin (Cal) concentration is elevated in acute inflammatory reactions and its increase in the plasma suggests a diagnostic potential for Cal assay. This study aimed (a) to evaluate the Cal plasma levels in patients suffering from acute pancreatitis (AP) and (b) to assess whether early assay of Cal plasma levels can be helpful in assessment of the severity of AP. Forty-six consecutive patients, median age 45 years, suffering from a first attack of AP were recruited at two medical centers. Data collected on admission included age, sex, delay between pain onset and admission, and Glasgow score. A severe outcome was defined according to the Atlanta criteria. AP was defined as edematous o…

Intestinal Scavenger Receptors Are Involved in Vitamin K 1 Absorption

2014

International audience; Vitamin K-1 (phylloquinone) intestinal absorption is thought to be mediated by a carrier protein that still remains to be identified. Apical transport of vitamin K-1 was examined using Caco-2 TC-7 cell monolayers as a model of human intestinal epithelium and in transfected HEK cells. Phylloquinone uptake was then measured ex vivo using mouse intestinal explants. Finally, vitamin K-1 absorption was compared between wild-type mice and mice overexpressing scavenger receptor class B type I (SR-BI) in the intestine and mice deficient in cluster determinant 36 (CD36). Phylloquinone uptake by Caco-2 cells was saturable and was significantly impaired by co-incubation with al…

Timing of activation of CD4+ memory cells as a possible marker to establish the efficacy of vaccines against contagious agalactia in sheep

2013

Mycoplasma agalactiae is a major pathogen of sheep and goats in many areas of the world and particularly in Mediterranean countries. It causes contagious agalactia, an infectious disease primarily affecting mammary glands. Many vaccines against the pathogen are currently under development. The aim of the study was to investigate the involvement of T cell-mediated immunity during vaccination and challenge experiments against Mycoplasma agalactiae. A comparison of the antigen-specific expansion of interferon gamma positive T cell memory and naïve subsets was performed between vaccinated and non-vaccinated sheep to identify cellular subsets whose activation was different between protected and …