Search results for "PLATE"
showing 10 items of 1689 documents
Defining Kawasaki disease and pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection during SARS-CoV-2 epidemic in…
2021
Abstract Background There is mounting evidence on the existence of a Pediatric Inflammatory Multisystem Syndrome-temporally associated to SARS-CoV-2 infection (PIMS-TS), sharing similarities with Kawasaki Disease (KD). The main outcome of the study were to better characterize the clinical features and the treatment response of PIMS-TS and to explore its relationship with KD determining whether KD and PIMS are two distinct entities. Methods The Rheumatology Study Group of the Italian Pediatric Society launched a survey to enroll patients diagnosed with KD (Kawasaki Disease Group – KDG) or KD-like (Kawacovid Group - KCG) disease between February 1st 2020, and May 31st 2020. Demographic, clini…
Cajal–Retzius and subplate cells: transient cortical neurons and circuits with long-term impact
2020
Abstract The laminar and columnar organization of the mature cerebral cortex is determined by a variety of early developmental processes. Two distinct populations of early generated neurons play important roles in corticogenesis. Cajal–Retzius neurons, located in the marginal zone (later layer 1), control the formation of neocortical layers by releasing the extracellular matrix protein reelin, which serves as a guiding signal for migrating neurons. Subplate neurons in the lower neocortical layer play an active role in axonal pathfinding of thalamocortical connections and in transient synaptic circuits, influence early cortical plasticity and the maturation of the columnar architecture. Both…
Electrical activity patterns and the functional maturation of the neocortex
2011
At the earliest developmental stages, sensory neocortical areas in various species reveal distinct patterns of spontaneous neuronal network activity. These activity patterns either propagate over large neocortical areas or synchronize local neuronal ensembles. In vitro and in vivo experiments indicate that these spontaneous activity patterns are generated from neuronal networks in the cerebral cortex, in subcortical structures or in the sensory periphery (retina, cochlea, whiskers). At early stages spontaneous periphery-driven and also sensory evoked activity is relayed to the developing cerebral cortex via the thalamus and the neocortical subplate, which amplifies the afferent sensory inpu…
Variable kinematics models and finite elements for nonlinear analysis of multilayered smart plates
2015
Abstract A variable kinematics approach for moderately large deflection analysis of smart magneto-electro-elastic multilayered plates is presented. The approach is based on the condensation of the electro-magnetic state into the plate kinematics, whose nonlinear strain–displacement relationships are expressed in the von Karman sense. This leads to models resulting in an effective mechanical plate, which takes the multifield coupling effects into account by the plate stiffness, inertia and loading characteristics, consistently defined as combinations of the layers material properties. By a unified approach, both equivalent single layer and layerwise models are developed formulating the assoc…
The polar method as a tool for solving inverse problems of the classical laminated plate theory
2000
Publisher Summary Fiber reinforced laminates are widely used in modem applications. For these kinds of structures, the Classical Laminated Plate Theory and its various extensions provide efficient methods for theoretical analysis, that is, when the stacking sequence, the orientations, and the properties of the individual laminas are known. For design of laminates, a very limited number of rules are available. For stiffriess design, two are currently known and used in practical applications: the Werren and Norris rule to get membrane isotropy, and the symmetrical sequence rule to suppress stretching/bending coupling. This chapter deals with the resolution of inverse problems of the Classical…
An equivalent single-layer approach for free vibrations analysis of smart laminated thick composite plates
2012
An equivalent single-layer model for the free vibration analysis of smart laminated plates is presented. The electric and magnetic fields are assumed to be quasi-static and third-order in-plane kinematics is employed to adequately take the shear influence into account when the plate thickness increases. The model governing equations are the plate equations of motion written in terms of mechanical primary variables and effective stiffness coefficients, which take the multifield coupling effects into account. The model shows that the surfaces magneto-electric boundary conditions enter the definitions of the laminate forces and moments resultants. Moreover, it reveals that new stiffness terms,…
Crust Formation and Plate Motion in the Early Archean
1992
Mounting evidence for voluminous continental crust formation in the early Archean involving intracrustal melting and selective preservation of granitoid rocks suggests that initial crust formation crust formation and growth were predominantly by magmatic underplating in plumegenerated Iceland-type settings. Collision of these early islands to give rise to larger blocks is suggested by extensive horizontal shortening in both supracrustal and granitoid assemblages. Preservation of early Archean high-grade gneisses that were once at depths of 20 to 30 kilometers implies that these blocks developed thick, subcrustal roots despite high mantle heat flow. Rigid continental plates must have existed…
Relations entre les variations climatiques, les perturbations du cycle du carbone et les crises de la production carbonatée : application au Crétacé …
2011
The Early Cretaceous is punctuated by carbon cycle perturbations, associated with organic matter burial episodes and carbonate production crises. These events coincide with short-term cooling (<1Ma), yet the mechanisms are still unclear, because of low resolution in sea surface temperature reconstructions. Recent climatic models suggest that carbonate-platform-collapse events may trigger a short-term ocean cooling episode (Donnadieu et al., accepted). In order to establish relations between climates and carbonate productions, we performed stratigraphic, palaeoecologic and geochemical analyses on Valanginian sediments from the La Charce-Vergol and the Ollioules sections (South-East France) a…
Numerical analysis of composite plates with multiple delaminations subjected to uniaxial buckling load
2006
Abstract In this paper the buckling and post-buckling behaviour of unidirectional and cross-ply composite laminated plates with multiple delaminations has been studied. Finite elements analyses have been performed, using a linear buckling model, based on the solution of the eigenvalues problem, and a non-linear one, based on an incremental-iterative method. With non-linear method large displacements have been taken into account and also contact constraints between sublaminates have been added to avoid their interpenetration. It has been found that both delamination length and position and stacking sequence of the plies influence the critical load of the plate; furthermore, linear and non-li…
Autologous adipose-derived stromal vascular fraction and platelet concentrates for the treatment of complex perianal fistulas
2022
Abstract Background Complex perianal fistulas are a major challenge for modern surgery since 10–35% of patients have functional problems after treatment. Sphincter-saving techniques have a wide range of efficacy (10–80%). We hypothesised that autologous adipose-derived stromal vascular fraction in combination with platelet rich plasma is a new therapeutic strategy with enhanced cure and function preservation rates. Methods Adult patients with complex cryptoglandular perianal fistulas were treated with injection of autologous adipose-derived stromal vascular fraction in combination with platelet rich plasma around and inside the fistulous tract between May 2018 and April 2019 at the General …