Search results for "PLE"

showing 10 items of 22773 documents

The interaction of novel transition metal complexes and ligands with biomolecular targets: kinetic, thermodynamic and computational investigations.

metal complexesDNA
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Heads or Tails? Sandwich-Type Metallocomplexes of Hexakis(2,3-di-O-methyl)-α-cyclodextrin

2020

Native and synthetically modified cyclodextrins (CDs) are useful building blocks in construction of large coordination complexes and porous materials with various applications. Sandwich-type complexes (STCs) are one of the important groups in this area. Usually, coordination of secondary hydroxyls or the “head” portal of native CD molecules to a notional multinuclear ring of metal cations leads to formation of head-to-head STCs. Our study introduces a new CD-ligand, hexakis(2,3-di-O-methyl)-α-cyclodextrin, which enables formation of intriguing head-to-head, but also novel tail-to-tail STCs. Homometallic silver-based head-to-head STCs, AgPF6-STC and AgClO4-STC, were obtained by coordination …

metal-organic materialrubidiumcyclodextrinsilversandwich-type complexX-ray crystallography
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Terahertz polarization-division multiplexing within a four-wire waveguide

2022

We demonstrate a new metal-wire waveguide topology, namely a four-wire waveguide, which simultaneously acts as a broadband terahertz polarization-division multiplexer and as a novel platform to realize the independent manipulation of polarization-division multiplexed terahertz signals.

metal-wire waveguidepolarizationmultiplexingTerahertzmetal-wire waveguidesmetal-wire waveguides; multiplexing; polarization; signal processing; Terahertzsignal processingSettore ING-INF/01 - Elettronica
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Wpływ warunków prowadzenia eksperymentu na wyniki badań biomonitoringowych z zastosowaniem mchów

2017

metale ciężkiebiomonitoring aktywnyPleurozium schreberi mosseswspółczynnik akumulacji względnej RAFmchy Pleurozium schreberirelative accumulation factor RAFheavy metalsatomic absorption spectrometryactive biomonitoringabsorpcyjna spektrometria atomowaProceedings of ECOpole
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Resorsinareenien metallikompleksit

2011

Tämän pro gradu -tutkielman kirjallisuusosa käsittelee resorsinareenien metallikomplekseja. Tarkastelussa on keskitytty erityisesti resorsinareenien metallikompleksien rakenteeseen ja koordinaatiogeometriaan. Tutkielma on jaoteltu siirtymä- ja alkalimetalleihin sitoutuviin resorsinareeneihin, ja nämä on jaoteltu vielä tarkemmin resorsinareenien mukaan. Kokeellisen osan tarkoituksena oli syntetisoida terpyridiinifunktionalisoitu resorsinareeni, joka pystyy muodostamaan metallikomplekseja. Aromaattiset amiinit ovat typpiatomiensa takia mielenkiintoisia substituenttiryhmiä. Yhdisteen terpyridiinisillat ovat hyviä koordinoitumaan useisiin eri metalleihin, kuten sinkkiin ja kupariin, juuri typpi…

metallikoordinaatiometallikompleksiresorsinareeni
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Interactive data-driven multiobjective optimization of metallurgical properties of microalloyed steels using the DESDEO framework

2023

Solving real-life data-driven multiobjective optimization problems involves many complicated challenges. These challenges include preprocessing the data, modelling the objective functions, getting a meaningful formulation of the problem, and supporting decision makers to find preferred solutions in the existence of conflicting objective functions. In this paper, we tackle the problem of optimizing the composition of microalloyed steels to get good mechanical properties such as yield strength, percentage elongation, and Charpy energy. We formulate a problem with six objective functions based on data available and support two decision makers in finding a solution that satisfies them both. To …

metallurgiaopen-source softwareinteractive optimizationpäätöksentukijärjestelmätmonitavoiteoptimointidata-driven evolutionary computationmultiple decision makersfysikaaliset ominaisuudetavoin lähdekoodioptimointiArtificial IntelligenceControl and Systems Engineeringinteraktiivisuussurrogate-assisted optimizationmetalliseoksetElectrical and Electronic Engineeringmultiple criteria optimization
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Amplicon-based high-throughput pooled sequencing identifies mutations in CYP7B1 and SPG7 in sporadic spastic paraplegia patients

2011

Hereditary spastic paraplegia (HSP) is a neurodegenerative disorder defined clinically by progressive lower limb spasticity and weakness. HSP is a genetically highly heterogeneous condition with at least 46 gene loci identified so far, involving X-linked, autosomal recessive (AR) and autosomal dominant inheritance. For correct diagnosis, molecular testing is essential because clinical parameters by themselves are not reliable to differentiate HSP forms. The purpose of this study was to establish amplicon-based high-throughput genotyping for AR-HSP. A sample of 187 index cases with apparently sporadic or recessive spastic paraplegia were analyzed by applying an array-based amplification stra…

methods [High-Throughput Nucleotide Sequencing]GenotypeHereditary spastic paraplegiaDNA Mutational AnalysisMolecular Sequence DataSPG7 protein humanCytochrome P450 Family 7diagnosis [Paraplegia]Biologymedicine.disease_causegenetics [Paraplegia]Cohort Studiesgenetics [Metalloendopeptidases]03 medical and health sciences0302 clinical medicineGenetic variationGenotypeGeneticsmedicineHumansddc:610Genetic TestingGenotypingGenetics (clinical)CYP7B1 protein human030304 developmental biologyGenetic testingParaplegiaGenetics0303 health sciencesMutationBase SequenceParapleginmedicine.diagnostic_testgenetics [Steroid Hydroxylases]Genetic VariationHigh-Throughput Nucleotide SequencingMetalloendopeptidasesmethods [DNA Mutational Analysis]Ampliconmedicine.diseasegenetics [Genetic Variation]3. Good healthMutationSteroid HydroxylasesATPases Associated with Diverse Cellular Activities030217 neurology & neurosurgeryClinical Genetics
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Bidentate [N, N] nickel complexes with salen type ligands for polymerization of methyl methacrylate

2008

Otrzymano kompleksy niklu [N,N]NiBr2, które po aktywacji związkiem glinoorganicznym zastosowano w polimeryzacji metakrylanu metylu (MMA). Dwukleszczowe ligandy [N,N] uzyskano zastępując w ligandach salenowych grupy hydroksylowe podstawione do pierścieni fenylowych różnymi grupami alkoksylowymi (OMe lub OCH2C6H5). Metyloalumoksan (MAO) okazał się skutecznym aktywatorem kompleksów niklu w polimeryzacji MMA. Same kompleksy bez aktywatora nie wykazywały żadnej aktywności. Stwierdzono, że aktywność badanych układów katalitycznych rośnie ze wzrostem stosunku molowego Al/Ni. W wyniku polimeryzacji w stosowanych warunkach otrzymano poli(metakrylan metylu) (PMMA) z przewagą triad syndiotaktycznych c…

methylalumoxanemetyloalumoksanmetakrylan metylupolymerizationzmodyfikowany ligand salenowynickel complexmodified salen ligandpolimeryzacjakompleks niklumethyl methacrylatePolimery
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Interaction of methyltin(IV) compounds with carboxylate ligands. Part 1: formation and stability of methyltin(IV)–carboxylate complexes and their rel…

2006

Quantitative data on the stability of mono-, di- and trimethyltin(IV)-carboxylate complexes (acetate, malonate, succinate, malate, oxydiacetate, diethylenetrioxydiacetate, tricarballylate, citrate, butanetetracarboxylate and mellitate) are reported at t=25°C and I → 0 mol l - 1 . Several mononuclear, mixed proton, mixed hydroxo and polynuclear species are formed in these systems. As expected, the stability trend is mono- > di- > trimethyltin(IV) and mono < di < tri < tetra < hexa for the organotin moieties and carboxylate ligands investigated, respectively. Moreover, ligands containing, in addition to carboxylic,-O-and-OH groups show a significantly higher stability with respect to analogou…

methyltin(IV) cationLigandStereochemistryMetal ions in aqueous solutionGeneral ChemistryHEXAMedicinal chemistryInorganic Chemistrymethyltin(IV)–carboxylate complexeschemistry.chemical_compoundMalonatechemistryspeciationStability constants of complexesmethyltin(IV) cationsChemical stabilitySettore CHIM/01 - Chimica AnaliticaCarboxylatemethyltin(IV)–carboxylate complexeBinding sitecarboxylate ligandmethyltin(IV) cations; carboxylate ligands; methyltin(IV)–carboxylate complexes; speciationcarboxylate ligands
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NUOVO METODO COMPLEMENTARE NON DISTRUTTIVO

2008

metodo complementarenon distruttivoSettore ICAR/11 - Produzione Ediliziacalcestruzzi
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