Search results for "PLE"

Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in …

2010

The organization and dynamics of microtubules (MTs) and the actin cytoskeleton are critical for the correct development and functions of neurons, including intracellular traffic and signaling. In vitro ethanol exposure impairs endocytosis, exocytosis, and nucleocytoplasmic traffic in astrocytes and alters endocytosis in cultured neurons. In astrocytes, these effects relate to changes in the organization and/or function of MTs and the actin cytoskeleton. To evaluate this possibility in hippocampal cultured neurons, we analyzed if chronic ethanol exposure affects the levels, assembly, and cellular organization of both cytoskeleton elements and the possible underlying mechanisms of these effec…

Detection of natural killer T cells in mice infected with Rickettsia conorii.

2013

Little information is available regarding the role of natural killer T (NKT) cells during the early stage of Rickettsia conorii infection. Herein, C3H/HeN mice were infected with the Malish 7 strain of R. conorii. Splenocytes from these mice were analysed in the early stage of the infection by flow cytometry and compared with uninfected controls. Our results showed an increase in NKT cells in infected mice. Additionally, NKT interleukin (IL)-17(+) cells increased three days after infection, together with a concurrent decrease in the relative amount of NKT interferon (IFN)-γ(+) cells. We also confirmed a higher amount of NK IFN-γ(+) cells in infected mice. Taken together, our data showed tha…

Introduzione a Mente e Corpo: Aspetti filosofici e scientifici

2005

Operators in Rigged Hilbert Spaces, Gel’fand Bases and Generalized Eigenvalues

2022

Given a self-adjoint operator A in a Hilbert space H, we analyze its spectral behavior when it is expressed in terms of generalized eigenvectors. Using the formalism of Gel’fand distribution bases, we explore the conditions for the generalized eigenspaces to be one-dimensional, i.e., for A to have a simple spectrum.

LAW AND SOCIAL CHANGE: RIGHT TO A NAME, PERSONAL IDENTITY AND PRIVATE LIFE IN CONTEXT

2014

The name is the key to identify a single individual and to link a person to her family, as well as the primary interface in the relationship between a person and the community he or she lives in. This study claims that private life and private autonomy are becoming interpretative arguments and vehicles to ensure that law would be able to follow – and sometimes to chase – social changes in personal and family life, in finding new rules to regulate the relationship between the individual, the family and public authorities or between a private individual and the community she interfaces with.1 Judicial interpretative activity often reveals legislative shortcomings. In particular, the judiciary…

The Effect of Mechanocatalytic Pretreatment on the Structure and Depolymerization of Willow

2020

In this study, the effect of a mechanocatalytic pretreatment on the structure of willow and sugar release from pretreated willow was explored. In the mechanocatalytic approach, the pretreatment consists of solvent-free impregnation with sulfuric acid and a mechanical treatment with ball milling. Willow sawdust and pretreated samples were analyzed with field emission scanning electron microscope and X-ray diffraction. The products in the sugar solution were determined as the total reducing sugars with the 3,5-dinitrosalicylic acid method and monosaccharides with capillary electrophoresis. According to the results, milling increased the sugar production, depending on the sulfuric acid load. T…

Ģenētiskās izmaiņas pārmantotās melanomas pacientiem Latvijā

2017

Melanoma ir multifaktoriāla slimība, kas attīstās ādas pigmenta šūnu, melanocītu, nekontrolētas dalīšanās rezultātā. Bakalaura darba mērķis bija izvērtēt izmaiņas augsta un vidēja riska melanomas jutības gēnos pacientiem, kuru anamnēzē ir vairāki saslimšanas gadījumi ar melanomu vai arī saslimšanas gadījumi ar aizkuņģa dziedzera audzēju vai nervu sistēmas audzēju. Kopā darbā izanalizēti 39 melanomas pacienti, 9 pacientu ģimenes locekļi un viens pacients ar acs melanomu. Ar paralēlo daudzķēžu sekvenēšanas metodi izanalizētajos 4 gēnos (BAP1, POT1, CDKN2A un MC1R) kopumā atrastas 11 nomaiņas. Papildus 3 analizētajos gēnos (TERT, CDK4 un MITF) izmaiņas atrastas netika. Kā potenciāli bīstamas n…

Una possible intepretazione junghiana dell’insight di Kekulé

2012

Rocking behaviour of multi-block columns subjected to pulse-typeground motion accelerations

2016

Ancient columns, made with a variety of materials such as marble, granite, stone or masonry are an important part of theEuropean cultural heritage. In particular columns of ancient temples in Greece and Sicily which support only the architrave arecharacterized by small axial load values. This feature together with the slenderness typical of these structural members clearlyhighlights as the evaluation of the rocking behaviour is a key aspect of their safety assessment and maintenance. It has to be notedthat the rocking response of rectangular cross-sectional columns modelled as monolithic rigid elements, has been widely investigatedsince the first theoretical study carried out by Housner (19…

Hacia la implementación de un modelo de atención temprana por parte de una Organización Paraguaya

2020

Implementation science has been developed to help understand why evidence-based practices are not adopted as rapidly as they might. We describe here the process a rehabilitation center in Paraguay is undergoing to transform itself into a state-of-the-art early intervention program. We describe the organization and its contextual strengths and barriers, the model it chose to implement, and the implementation procedures it has attempted. The implications for model fidelity are highlighted, as this organization needed to make adaptations to the model as designed, to fit the particular context of its mission and the Paraguayan culture. Features of the Routines-Based Model are described.  La cie…