Search results for "PLIF"

showing 10 items of 835 documents

Multiple Non-linear Reservoirs to Model Water Balance Components in Sandy Soils

2023

In the hydrologic literature, to model water flow in unsaturated soils, the Richards equation is usually applied, allowing the main components of the hydrologic cycle, as rainfall partitioning into surface runoff and infiltration, to be determined. The Richards equation is highly nonlinear, making very challenging to derive analytical solutions. Recently, for constant rainfall intensity, under the simplified hypothesis of gravity-driven infiltration, and by assuming a capacitance framework, a simplified solution of the Richards equation that considers the Brooks and Corey hydraulic conductivity function was suggested. By maintaining the assumption that the infiltration process is dominated …

Settore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliGravity-driven infiltration non-linear reservoirs sandy soils simplified solutions water balance components
researchProduct

Gene amplification in fibroblasts from ataxia telangiectasia (AT) patients and in X-ray hypersensitive AT-like Chinese hamster mutants

2001

In search of functions involved in the regulation of gene amplification, and given the relevance of chromosome breakage in initiating the process, we analyzed the gene amplification ability of cells hypersensitive to inducers of DNA double-strand breaks and defective in cell cycle control: two human fibroblast strains derived from patients affected by ataxia telangiectasia (AT) and two hamster mutant cell lines belonging to complementation group XRCC8 of the rodent X-ray-sensitive mutants. These mutants are considered hamster models of AT cells. To measure gene amplification, the frequency and the rate of occurrence of N-(phosphonacetyl)-l-aspartate resistant cells were determined. In both …

Settore BIO/18 - GeneticaCancer Research gene amplification DNA repair
researchProduct

Metilazione del DNA in artrite reumatoide

2005

Lo stato di metilazione del DNA genomico e del gene PTHrP è stato valutato con tecniche molecolari e citogenetiche in artrite reumatoide (AR), patologia autoimmune caratterizzata anche da alta incidenza di linfomi e da ipercalcemia per overespressione del gene PTHrP. La metilazione del DNA, infatti, ha un ruolo critico nello sviluppo delle malattie neoplastiche; il gene PTHrP avendo tre promotori uno dei quali contiene un’isola CpG è un buon candidato per la deregolazione da alterato pattern di metilazione locale. Le indagini sulla metilazione genomica, condotte su DNA estratto da sangue periferico di pazienti e di donatori e amplificato in reazioni di Methylation-Sensitive Arbitrarily Prim…

Settore BIO/18 - Geneticainstead chromosomes of controls were almost uniformly decorated by brilliant grains. Studies on methylation of PTHrP gene promoter 2 performed on five CpG island internal sites using the Methylation-Sensitive Restriction Endonuclease Multiplex (MSREM)-PCR showed that one of the sites nearest the trascription starting point is heavy methylated in a significantly high number of RA patients. Thus RA seems to be characterized by genomewide hypomethylation associated with local hypermethylation like the most part of tumors. This result raises the possibility that susceptibility to lymphomas is related to abnormal DNA methylation levels and suggests the opportunity to evaluate the DNA methylation status in RA patientin fact the demethylating therapies together with diet and life style can act towards an increase of tumor risk. Future studies using a larger number of subjects could confirm these findings.Rheumatoid Arthritis (RA) is a chronic multisystem inflammatory disease characterized by high recurrence of lymphomas as well as hypercalcemia due to PTHrP overexpression. Because of DNA methylation plays a critical role in development of neoplasias we determined in RA patients the global DNA methylation status and local methylation pattern of the CpG island of one of the three promoters of PTHrP gene utilizing molecular and cytogenetic techniques. Investigations performed on DNA from peripheral blood of patients and donors amplified by Methylation-Sensitive Arbitrarily Primed (MeS-AP)-PCR indicated that RA is strongly associated with global DNA hypomethylation. Similarly chromosomal DNA methylation pattern analysis by indirect immunofluorescence technique with anti 5-methylcitosine antibody showed all peripheral lymphocyte metaphases from RA patients with chromosomes weakly fluorescent without discrete grain
researchProduct

Comparing marine geology and coastal geomorphology vertical tectonic data, a case study between Acquedolci and Patti (Messina)

2011

The study of new data on vertical movements show a complex geologic response in a restricted sector of coastal area between Acquedolci and Patti (north-eastern Sicily). Different surveys allowed to the recognition of morphological, biological and archaeological markers of paleo-sea level. The analysis of these markers and the absolute datings performed, allowed to reconstruct the history of vertical deformation of this sector but only the comparison among coastal geomorphological data and marine geological data of platform-scarp continental system associates, allowed to find the necessary keys words to explain the geologic complexity of this sector.

Settore GEO/02 - Geologia Stratigrafica E SedimentologicaCoastal geomorphology Tectonic uplift North-eastern Sicily
researchProduct

Spatial extent of recent vertical tectonic motions misured in NE Sicily coastal area. Insights from marine geology and coastal geomorphology studies.

2011

Vertical position of sea-level, pointed out by related deposits and morphologies, provide useful markers to estimate tectonic uplift rates. For the Holocene very high uplift rates are misured in the northeast Sicily coast (Antonioli et al., 2009). This study compare vertical tectonic movements and marine geology data in the coastal sector between Capo d’Orlando and Brolo (NE Sicily); tectonic lineaments show different trends both onland (Nigro & Sulli, 1995) and offshore (Nicolich et al.,1982) and also the morphological response follow closely this difference. The geomorphologic survey provided data on Holocene uplift rates. We studied an archaeological ancient quarry of grinding wheels for…

Settore GEO/02 - Geologia Stratigrafica E SedimentologicaCoastal geomorphology Tectonic uplift North-eastern Sicily Marine geology
researchProduct

Neotectonic uplift and tilting of crustal blocks in Northern Sicily

2009

La Sicilia settentrionale è caratterizzata da un’intensa attività sismica che è espressione di deformazioni attive. In questo settore dell’Isola affiora il nucleo della catena neogenica delle Magrebidi occidentali, che è sottoposto ad intenso sollevamento durante il Plio-Pleistocene. Le deformazioni più recenti sono, in gran parte, rappresentate da sistemi di faglie estensionali e trascorrenti. Il tasso di sollevamento non è uniforme, così come suggerisce la differente elevazione dei depositi di questo periodo. Essi affiorano lungo il settore costiero settentrionale e la loro quota decresce complessivamente dall’estremità nord-est a quella nord-ovest della Sicilia. Le deformazioni più recen…

Settore GEO/03 - Geologia Strutturaleneotectonic faults morphometric pattern uplift crustal blocks Sicily"Neotectonic uplift"
researchProduct

some morphological effects related to a non-uniform uplifting of crustal bloks in Northern Sicily (Central Mediterranean

2010

Settore GEO/03 - Geologia Strutturaleuplift crustal blocks morphological effects Sicily
researchProduct

Future coastal hazard scenarios. A case study in NE Sicily (Italy)

2012

The coastal dynamics is the result of several causes that contribute to change the balance of beach deposits over time. The beach system is not always able to maintain coastal balance: the factors contributing to this phenomenon are to be found in both natural and anthropogenic spheres. In this context we present the analysis of marine geology and coastal geomorphological data of a sector between Rocca di Caprileone and Tindari (north-eastern Sicily) with the aim to: i) determine their onland-offshore area relationships, ii) analyze which natural features may contribute to coastal retreat, iii) present coastal hazard scenarios. Until fifty years ago the natural balance of this coastal area …

Settore GEO/04 - Geografia Fisica E GeomorfologiaCoastal hazard NE Sicily uplift rate canyon heads relative sea level projections
researchProduct

Flank Margin Caves In Telogenetic Limestones In Italy

2017

Almost 20% of Italy is characterized by the outcropping of carbonate massifs ranging in age from Cambrian to Quaternary. Coastal karst is present in many Italian regions: from North-East to South and West: the Gulf of Trieste, the Conero (South of Ancona, Marche), the Adriatic coast of Apulia including Gargano, Murge and Salento, Maratea in Basilicata, Cilento in Campania, Circeo and Gaeta in Latium, Argentario and Giannutri Island in Tuscany, the southernmost part of the Ligurian Alps, Palermo Mts., San Vito Lo Capo, Syracuse coast and Marettimo Island in Sicily, and, especially, in Sardinia, which has carbonate rocks touching the sea along the coast of Balai near Porto Torres, Capo Caccia…

Settore GEO/04 - Geografia Fisica E GeomorfologiaKarstsalt-fresh water mixing coastal karst cave geomorphology coastal uplift speleogenesis
researchProduct

MILLSTONES COASTAL QUARRIES AS INDICATOR OF RELATIVE SEA LEVEL CHANGES

2012

The Italian coasts shows numerous archaeological remains which reveals the activities that were carried out along the coast for thousands of years of history. In order to use archaeological structures for coastal studies, an accurate estimate of their relationship to the sea level at the time of construction is required (Lambeck et al 2004, Antonioli et al 2007, Auriemma & Solinas 2009). Millstone coastal quarries are only documented in southern Italy; they are carved on beachrock, calcarenites and other sedimentary rock easy to be exploited. Few archaeological information have been published about quarries for millstones extraction; they are documented since around 2500 yr BP (Amouretti, 1…

Settore GEO/04 - Geografia Fisica E GeomorfologiaUplift ratearchaeological markerMillstone coastal quarry
researchProduct