Search results for "PLIN2"

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Effects of Long-Term Physical Activity and BCAA Availability on the Subcellular Associations between Intramyocellular Lipids, Perilipins and PGC-1&al…

2023

Cellular skeletal muscle lipid metabolism is of paramount importance for metabolic health, specifically through its connection to branched-chain amino acids (BCAA) metabolism and through its modulation by exercise. In this study, we aimed at better understanding intramyocellular lipids (IMCL) and their related key proteins in response to physical activity and BCAA deprivation. By means of confocal microscopy, we examined IMCL and the lipid droplet coating proteins PLIN2 and PLIN5 in human twin pairs discordant for physical activity. Additionally, in order to study IMCLs, PLINs and their association to peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) in cytosolic…

lipid dropletsOrganic Chemistryphysical activityGeneral MedicineaminohapotliikuntalipiditCatalysisComputer Science ApplicationsInorganic ChemistryPLIN2PLIN5terveysvaikutuksetsubcellular localizationelectrical pulse stimulationproteiinitC2C12Physical and Theoretical Chemistryskeletal muscleEPSaineenvaihduntaMolecular Biologyfyysinen aktiivisuusSpectroscopyInternational Journal of Molecular Sciences
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