Search results for "PLOT"

showing 10 items of 830 documents

Eco-efficiency assessment under natural and managerial disposability: an empirical application for Chilean water companies.

2022

Getting a good understanding regarding the economic and environmental performance of water utilities is of great importance to achieve the goal of an efficient and sustainable industry. In this study, we apply the range adjusted measure (RAM) data envelopment analysis (DEA) model to evaluate the integrated (production and environmental) efficiency of several water utilities located in Chile. Integrated efficiency is evaluated using the concepts of natural and managerial disposability. This approach further allows us to quantify the contribution of each input and undesirable product on efficiency scores. The results highlighted that the Chilean water industry showed high levels of production…

Health Toxicology and MutagenesisEnvironmental ChemistryRecursos hidràulics ExplotacióGeneral MedicineEcologia aquàticaPollutionDesenvolupament econòmic Aspectes ambientalsEnvironmental science and pollution research international
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Refined analysis of genetic variability parameters in hepatitis C virus and the ability to predict antiviral treatment response.

2008

Summary.  Hepatitis C virus (HCV) infects approximately 3% of the world population. The chronicity of hepatitis C seems to depend on the level of genetic variability. We have recently (Torres-Puente et al., J Viral Hepat, 2008; 15: 188) reported genetic variability estimates from a large-scale sequence analysis of 67 patients infected with HCV subtypes 1a (23 patients) and 1b (44 patients) and related them to response, or lack of, to alpha-interferon plus ribavirin treatment.. Two HCV genome regions were analysed in samples prior to antiviral therapy, one compressing the three hypervariable regions of the E2 glycoprotein and another one including the interferon sensitive determining region …

Hepatitis C virusMutation MissenseAlpha interferonHepacivirusBiologyViral Nonstructural Proteinsmedicine.disease_causeAntiviral AgentsNucleotide diversityViral Envelope ProteinsVirologyDrug Resistance ViralRibavirinmedicineHumansGenetic variabilityNS5AGeneticsHepatologyHaplotypeGenetic VariationHepatitis CHepatitis C Chronicmedicine.diseaseVirologyHypervariable regionInfectious DiseasesTreatment OutcomeHaplotypesInterferonsJournal of viral hepatitis
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Ancient Haplotypes at the 15q24.2 Microdeletion Region Are Linked to Brain Expression of MAN2C1 and Children's Intelligence

2016

The chromosome bands 15q24.1-15q24.3 contain a complex region with numerous segmental duplications that predispose to regional microduplications and microdeletions, both of which have been linked to intellectual disability, speech delay and autistic features. The region may also harbour common inversion polymorphisms whose functional and phenotypic manifestations are unknown. Using single nucleotide polymorphism (SNP) data, we detected four large contiguous haplotype-genotypes at 15q24 with Mendelian inheritance in 2,562 trios, African origin, high population stratification and reduced recombination rates. Although the haplotype-genotypes have been most likely generated by decreased or abse…

HeredityAutism Spectrum DisorderIntelligenceSocial SciencesChromosome DisordersMAN2C1 geneFamiliesMicePsychologylcsh:ScienceChildChildrenIn Situ HybridizationCognitive ImpairmentIntelligence Testseducation.field_of_studyIntelligence quotientBrainGenomicsNeurologyChromosome DeletionHumanGenotypeEvolutionSingle-nucleotide polymorphismFluorescenceEvolution Molecular03 medical and health sciencesalpha-MannosidaseIntellectual DisabilityMannosidasesGeneticsChromosome 15q24 2HumansPolymorphismeducationChromosome Aberrationslcsh:RHaplotypePair 15PongoBiology and Life SciencesComputational BiologyMolecularmedicine.diseaseIntellectual Disability/genetics030104 developmental biologyNeurodevelopmental DisordersDevelopmental PsychologyAfricalcsh:QPopulation GroupingsGene expressionEthiopiaAutismePopulation GeneticsNeuroscience0301 basic medicineAutismlcsh:MedicineGene ExpressionHomozygosityGeographical LocationsCohort StudiesChromosome Disorders/geneticsIntellectual disabilityMedicine and Health SciencesIn Situ Hybridization FluorescenceSegmental duplicationMannosidases/geneticsGeneticsMultidisciplinaryGenomeCognitive NeurologyHomozygoteSingle NucleotidePhenotypesymbolsInfantsResearch ArticleCognitive NeurosciencePopulationInfants -- DesenvolupamentBiologyPolymorphism Single NucleotideChromosomessymbols.namesakeDevelopmental NeurosciencemedicineAnimalsBrain/metabolismCromosomes humans -- AnomaliesAlleleChromosomes Human Pair 15Evolutionary BiologyPopulation BiologyGenome HumanChromosome 15qIntelligence/geneticsGenome AnalysisGenomic LibrariesExpressió gènicaMacaca mulattaRatsHaplotypesAge GroupsPeople and PlacesMendelian inheritanceCognitive Science
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Correction: Phylogeny of the Eurasian Wren Nannus troglodytes (Aves: Passeriformes: Troglodytidae) reveals deep and complex diversification patterns …

2020

The Mediterranean Basin represents a Global Biodiversity Hotspot where many organisms show high inter- and intraspecific differentiation. Extant phylogeographic patterns of terrestrial circum-Mediterranean faunas were mainly shaped through Pleistocene range shifts and range fragmentations due to retreat into different glacial refugia. Thus, several extant Mediterranean bird species have diversified by surviving glaciations in different hospitable refugia and subsequently expanded their distribution ranges during the Holocene. Such a scenario was also suggested for the Eurasian Wren (Nannus troglodytes) despite the lack of genetic data for most Mediterranean subspecies. Our phylogenetic mult…

HeredityBiochemistryGeographical LocationsSongbirdsPleistocene EpochAfrica NorthernEnergy-Producing OrganellesPhylogenyData ManagementMultidisciplinaryQuaternary PeriodGeographyFossilsQRPhylogenetic AnalysisGeologyBiodiversityBiological EvolutionFossil CalibrationMitochondriaPhylogeneticsEuropeGenetic MappingPhylogeographyBiogeographyMedicineCellular Structures and OrganellesResearch ArticleGenetic MarkersComputer and Information SciencesMitochondria ; Fossil calibration ; Haplotypes ; Europe ; Phylogenetic analysis ; Phylogeography ; Paleogenetics ; Pleistocene epochScienceBioenergeticsDNA MitochondrialGeneticsAnimalsEvolutionary SystematicsTaxonomyEvolutionary BiologyPopulation BiologyEcology and Environmental SciencesBiology and Life SciencesPaleontologyCorrectionGenetic VariationGeologic TimeCell BiologyHaplotypesPeople and PlacesEarth SciencesCenozoic EraPaleogeneticsPopulation Genetics
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Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers

2012

Introduction: Cis-acting regulatory single nucleotide polymorphisms (SNPs) at specific loci may modulate penetrance of germline mutations at the same loci by introducing different levels of expression of the wild-type allele. We have previously reported that BRCA2 shows differential allelic expression and we hypothesize that the known variable penetrance of BRCA2 mutations might be associated with this mechanism. Methods: We combined haplotype analysis and differential allelic expression of BRCA2 in breast tissue to identify expression haplotypes and candidate cis-regulatory variants. These candidate variants underwent selection based on in silico predictions for regulatory potential and di…

HeterozygoteColorectal-cancerPredisposition[SDV.CAN]Life Sciences [q-bio]/CancerSingle-nucleotide polymorphismRegulatory Sequences Nucleic AcidBiologyPolymorphism Single NucleotideAssociation03 medical and health sciences0302 clinical medicineBreast cancerGermline mutation[SDV.CAN] Life Sciences [q-bio]/CancerReference ValuesmedicineHumansGenetic Predisposition to DiseaseAllelic imbalanceGene-expressionAllelePromoter Regions Geneticskin and connective tissue diseases030304 developmental biologyMedicine(all)BRCA2 ProteinGenetics0303 health sciencesHuman genomeCarcinomaHaplotypemedicine.diseasePenetranceCommon3. Good healthGene Expression Regulation NeoplasticMinor allele frequencyGene Expression RegulationHaplotypesRegulatory sequence030220 oncology & carcinogenesisBeadarrayCancer researchFemaleCell-lineTranscription FactorsResearch ArticleBreast Cancer Research
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Population structure and mitochondrial DNA gene flow in Old World populations of Drosophila subobscura

1992

An extensive survey of mitochondrial DNA (mtDNA) restriction polymorphism in 156 isofemale lines from 29 different geographic populations of Drosophila subobscura distributed throughout the Old World was carried out. Ten restriction enzymes were used, five of which revealed restriction site polymorphism. Of the 31 restriction sites detected, 13 were found to be polymorphic. Comparisons with the mtDNA map of Drosophila yakuba indicate that the variable sites are mainly concentrated in protein genes, especially those corresponding to the NADH complex. A total of 13 different haplotypes were observed, two of which (haplotypes I and II) are quite frequent and widely distributed throughout the p…

HeterozygoteMitochondrial DNAPopulationPopulation geneticsDNA MitochondrialGene FrequencyGeneticsAnimalseducationAllelesGenetics (clinical)Geneticseducation.field_of_studybiologybiology.organism_classificationDrosophila subobscuraIsoenzymesRestriction Site PolymorphismRestriction siteGenetics PopulationHaplotypesDrosophilaFemaleRestriction fragment length polymorphismPolymorphism Restriction Fragment LengthDrosophila yakubaHeredity
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COVID-19, Terrorism, and Conspiracy Plot: Everyone Is Guilty Until Proven Innocent

2021

COVID-19 is reaffirming the tendency of nation-states to find imaginary enemies when hit with a crisis—enemies to whom its origins and perpetuation could be attributed. This is needed for their unity and survival. However, a strong and serious global pandemic like COVID-19 would need the identification of strong and serious enemies. This is a dangerous proposition if taken to anywhere beyond rhetoric. China is identified as the antagonist; yet, a real confrontation with China would cause more harm than what COVID-19 might cause. It is essential that we lead the world toward a new war, “against a virus”. This chapter reflects the problem of hospitality, as strongly associated with conspiracy…

Historybusiness.industrymedia_common.quotation_subjectEnvironmental ethicsPostmodernismPoliticsHarmHospitalityRhetoricTerrorismPlot (narrative)businessThe Imaginarymedia_common
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Physical and hydraulic characterization of a clay soil at the plot scale

2010

Summary The soil physical and hydraulic properties have to be determined for interpreting and simulating many hydrological processes. An investigation was carried out to determine the physical and hydraulic characteristics of a clay soil at the plot scale. An intensive sampling of the surface soil layer of two plots of 4 × 11 m2 was carried out by measuring, for each plot, dry soil bulk density, ρb, and antecedent soil water content, θi, at 88 sampling points and field-saturated soil hydraulic conductivity, Kfs, at 176 sampling points. A wide range of Kfs values (0.7–5107 mm h−1) were measured by the Simplified Falling Head (SFH) technique. For each variable, the two plots yielded very simi…

Hydrological processeSampling (statistics)Soil physical propertieSoil scienceStandard deviationHydraulic conductivitySample size determinationSoil hydraulic propertiePlot scaleSoil waterSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliSpatial variabilityFrequency distributionWater contentWater Science and TechnologyMathematics
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USING A TRANSIENT INFILTROMETRIC TECHNIQUE FOR INTENSIVELY SAMPLING FIELD-SATURATED HYDRAULIC CONDUCTIVITY OF A CLAY SOIL IN TWO RUNOFF PLOTS

2012

Point measurement of soil properties allows to explain and simulate plot scale hydrological processes. An intensive sampling was carried out at the surface of an unsaturated clay soil to measure, on two adjacent plots of 4×11 m2 and two different dates (May 2007 and February-March 2008), dry soil bulk density, rb, and antecedent soil water content, qi, at 88 points. Field-saturated soil hydraulic conductivity, Kfs, was also measured at 176 points by the transient Simplified Falling Head technique to determine the soil water permeability characteristics at the beginning of a possible rainfall event yielding measurable runoff. The rb values did not differ significantly between the two dates b…

Hydrological processeSoil hydraulic propertiePlot scaleSoil physical propertieSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-Forestali
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MANUAL SAMPLING AND TANK SIZE EFFECTS ON THE CALIBRATION CURVE OF PLOT SEDIMENT STORAGE TANKS

2004

In many experimental soil erosion plots, runoff is collected and carried by a conveyance system to a sequence of storage tanks. If the soil loss is measured by collecting, after mixing, samples of the stored suspension, then a calibration curve between the actual mean concentration (C) and the measured concentration (Cm) in the storage tank occurs. The aim of this article was to evaluate experimentally the factors affecting the relationship between C and Cm. For a sandy loam soil, the replicated measurements of Cm (20 samples) for two values of the actual concentration (C = 5 and 25 g/L) showed that the variability of the measurements of Cm is low and confirmed the reliability of a calibrat…

HydrologyCalibration curveLoamStorage tankCalibrationSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliEnvironmental scienceSampling (statistics)SedimentSurface runoffAgricultural and Biological Sciences (miscellaneous)Calibration Sediment concentration Soil erosion measurement Soil erosion plotWater levelTransactions of the ASAE
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