Search results for "PLOT"
showing 10 items of 830 documents
Major histocompatibility complex regulation of the class of the immune response: the H-2d haplotype determines poor interferon-γ response to several …
1990
The lymph node cells of CBA (H-2k), but not BALB/c (H-2d) mice, release interferon (IFN)-gamma into the supernatant when immunized with picryl chloride epicutaneously and then exposed to antigen (haptenized cells) in vitro 4 days later. The failure in IFN-gamma production maps to the major histocompatibility complex (MHC; H-2d) in the congenic BALB/c, BALB/k and BALB/b mice. The evidence that this is an MHC regulation of the class of response to a range of antigens and not a classical Ir gene effect is (a) the difference is seen with several antigens including picryl chloride, "oxazolone" and purified protein derivative of tuberculin and (b) BALB/c mice, which fail to produce IFN-gamma, sho…
TNFA promoter polymorphisms and narcolepsy
2003
Narcolepsy is a debilitating sleep disorder that affects up to 0.05% of individuals in Caucasian populations. It is highly associated with the HLA-DR2 group antigen or the HLA-DRB1*1501-DQB1*0602 haplotype, respectively. However, the HLA association by itself cannot sufficiently explain the increased risk to family members, as HLA-DR2 is quite common in the general population and most people harboring the respective genotype do not develop any symptoms of narcolepsy. Situated in the HLA class II region, the TNFA gene is translated into the pro-inflammatory cytokine TNF-alpha. TNFA promoter polymorphisms have been linked to several inflammatory and autoimmune diseases. We analyzed three SNP …
Phylogeography and genetic variation of Triatoma dimidiata, the main Chagas disease vector in Central America, and its position within the genus Tria…
2008
Background Among Chagas disease triatomine vectors, the largest genus, Triatoma, includes species of high public health interest. Triatoma dimidiata, the main vector throughout Central America and up to Ecuador, presents extensive phenotypic, genotypic, and behavioral diversity in sylvatic, peridomestic and domestic habitats, and non-domiciliated populations acting as reinfestation sources. DNA sequence analyses, phylogenetic reconstruction methods, and genetic variation approaches are combined to investigate the haplotype profiling, genetic polymorphism, phylogeography, and evolutionary trends of T. dimidiata and its closest relatives within Triatoma. This is the largest interpopulational …
Explotación en línea de obras y prestaciones protegidas por el derecho de autor: objeto, sujetos, contenido y límites.
2015
El objeto de estudio se centra en el análisis de los principales problemas y cuestiones que suscita hoy la explotación en línea de los contenidos protegidos por el Derecho de autor. Para ofrecer un tratamiento más didáctico y clarificador hemos adoptado en nuestro análisis una estructura clásica de derecho subjetivo, de acuerdo con sus elementos definitorios y delimitadores, sujeto, objeto, contenido y límites. Estos elementos vertebran las cuatro partes en las que se estructura la tesis, precedidas de una introducción en la que hemos fijado el marco de referencia de nuestro estudio. A través de este estudio, siguiendo este esquema expositivo, desde la propia estructura o armazón jurídico d…
Naciones Unidas / 1. El naufragio
2005
La explotación minera de la Sierra de Cartagena (1840-1919)
1966
One Species, Hundreds of Subspecies? New Insight into the Intraspecific Classification of the Old World Swallowtail (Papilio machaon Linnaeus , 1758)…
2022
The Old World swallowtail Papilio machaon Linnaeus, 1758 is one of the most well-known and most characteristic members of the family Papilionidae. Over the past two centuries, the butterfly has been the subject of many studies. P. machaon is characterised by a tendency to change the wing colour pattern. In turn, due to the great interest of collectors and amateur entomologists, these studies have been converted into the description of over 100 colour forms, aberrations and subspecies. In this study, mitochondrial DNA (mtDNA), 16S rDNA and cytochrome b sequences were used to examine the correlation between the intraspecific classification and genetic structure of P. machaon. The study used 8…
Species cohesion despite extreme inbreeding in a social spider.
2011
Colonial social spiders experience extreme inbreeding and highly restricted gene flow between colonies; processes that question the genetic cohesion of geographically separated populations and which could imply multiple origins from predecessors with limited gene flow. We analysed species cohesion and the potential for long-distance dispersal in the social spider Stegodyphus dumicola by studying colony structure in eastern South Africa and the cohesion between this population and Namibian populations previously published. Data from both areas were (re)analysed for historic demographic parameters. Eastern South African S. dumicola were closely related to an east Namibian lineage, showing coh…
Comment on “Determining soil erodibility for the USLE-MM rainfall erosion model by P.I.A. Kinnell”
2018
Abstract The measurements units of the USLE-MM soil erodibility factor are dependent on the exponent of the erosivity term. This circumstance prevents to compare soil erodibility values of sites differing by the value of this exponent. To overcame this problem, Kinnell (2018) suggested to relate the soil erodibility factor of the USLE-MM with that of USLE-M by a linear relationship with the objective to obtain a soil erodibility factor independent of the power of the erosivity term. The USLE-MB, which is a recently proposed model, has also a soil erodibility factor having measurement units common to USLE modelling environment. Kinnell (2018) also showed that the relationship between the pow…
Los clásicos como resistencia: la lectura literaria en el marco de una educación lectora transmedia
2021
espanolActualmente, existe una propagacion de titulos narrativos inspirados por estructuras argumentales, personajes, temas y arquetipos procedentes de diversos clasicos literarios, historias que trascienden las paginas de los libros y llegan a las grandes pantallas de cine, a las pequenas de los dispositivos moviles o a plataformas diversas de entretenimiento interactivo: diversos servicios de streaming e incluso videojuegos. La lectura literaria hoy en dia implica la expansion de la cultura escrita y los referentes literarios a traves de modos multiples y medios de expresion mediante formas de interpretacion que integran diferentes tipos de discursos (textuales, visuales, sonoros, interac…