Search results for "PLR"

showing 3 items of 3 documents

Psoriātiska artrīta pacientu terapijas izvērtējums P.Stradiņa KUS Reimatoloģijas centrā

2016

Tēmas aktualitāte: pēdējos gados zinātniskās literatūras dati norāda par pētījumiem par NLR, PLR, MPV, CRO lietošanu psoriātiskā artrīta (PsA) pacientu slimības aktivitātes un terapijas efektivitātes novērtēšanā (Kim D.S. et all 2015), (Fu H. et all 2015), (Kisacik B. et all 2008), (Yazici S. et all 2010). Pētījuma mērķis: Izvērtēt PsA pacientu CRO, EGĀ, NLR, PLR un MPV rādītāju noteikšanas nepieciešamību ārstēšanas laikā. Metodes un materiāli: Pētījums izstrādāts P. Stradiņa KUS Reimatoloģijas centrā. Pētījumā iekļauti 39 pacienti, kuriem bija diagnosticēts PsA. PsA pacienti tika sadalīti divās grupās – pēc slimošanas ilguma, un pēc saņemtās terapijas. Šo grupu ietvaros analizējām CRO, EGĀ…

CROPLRPsoiātiskais artrītsMPVMedicīnaNLR
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Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Outcomes with Nivolumab in Pretreated Non-Small Cell Lung Cancer (NSCLC…

2020

Introduction: Immune checkpoint inhibitors have provided substantial benefit in non-small cell lung cancer (NSCLC) with unprecedented results in terms of survival. However, the identification of reliable predictive biomarkers to these agents is lacking and multiple clinicopathological factors have been evaluated. The aim of this study was to analyze the potential role of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lactate dehydrogenase (LDH) levels in patients with pretreated NSCLC receiving nivolumab. Methods: This was a retrospective multicenter study involving 14 Italian centers, evaluating the role of some laboratory results in patients with NSCLC treat…

OncologyMale030213 general clinical medicineLung NeoplasmsNeutrophilsLymphocytenon-small cell lung cancer (NSCLC)DiseaseNSCLCchemistry.chemical_compoundLeukocyte Count0302 clinical medicineAntineoplastic Agents ImmunologicalCarcinoma Non-Small-Cell LungPD-180 and overLeukocytesPharmacology (medical)LymphocytesNon-Small-Cell LungAged 80 and overbiologyGeneral MedicineMiddle AgedPrognosisImmunologicalmedicine.anatomical_structureNivolumab030220 oncology & carcinogenesisLDH; Nivolumab; NLR; NSCLC; PD-1; PD-L1; PLR; Prognosis; Adult; Aged; Aged 80 and over; Antineoplastic Agents Immunological; Biomarkers; Carcinoma Non-Small-Cell Lung; Female; Humans; Leukocyte Count; Leukocytes; Lung Neoplasms; Lymphocytes; Male; Middle Aged; Neutrophils; Nivolumab; Prognosis; Retrospective StudiesFemaleNivolumabAdultPD-L1medicine.medical_specialtyLDHAntineoplastic AgentsPLRNONLR03 medical and health sciencesPD-L1Lactate dehydrogenaseInternal medicinemedicineHumansNeutrophil to lymphocyte ratioAgedRetrospective Studiesbusiness.industryCarcinomamedicine.diseaseRheumatologychemistrybiology.proteinLDH; Nivolumab; NLR; NSCLC; PD-1; PD-L1; PLR; PrognosisbusinessBiomarkers
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Significance of Neutrophil to Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) in Diabetic Foot Ulcer and Potential New Therapeutic Targets

2021

Diabetic foot ulcer (DFU) is a well-known complication of diabetes and a significant burden on the national health systems. The neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio are inexpensive and easily accessible biomarkers that have proved to be useful in several inflammatory, infectious and cardiovascular diseases. We carried out a comprehensive review examining the association of NLR and PLR with the onset and progression of DFU. PLR and NLR were significantly increased in patients with DFU, compared with a control group of T2DM patients without DFU, and correlate well with DFU severity, evaluated by Wagner and IWGDF grading scales. In patients with diabetic foot infect…

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentOsteomyelitisGeneral MedicineSystemic inflammationmedicine.diseaseGastroenterologyDiabetic foot ulcerAmputationDiabetes mellitusInternal medicinediabetes diabetic foot ulcer inflammation neutrophil-to-lymphocyte ratio (NLR) platelet lymphocyte ratio (PLR)medicineSurgeryClinical significancemedicine.symptomNeutrophil to lymphocyte ratioComplicationbusiness
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