Search results for "PN"
showing 10 items of 2154 documents
Is the implementation of a microbiological surveillance screening beneficial in a neonatal intensive care unit?
2015
s of the 51st Workshop for Pediatric Research 51st Workshop for Pediatric Research Gottingen, Germany 16-17 April 2015 This supplement has not been sponsored. Meeting abstracts Background and aims Bacteria that cause nosocomial infections have often been found to colonize the patient's skin, respiratory tract or gastrointestinal tract previously. In 2012 and 2013, the German Commission for Hospital Hygiene and Infectious Disease Prevention recommended a microbiological screening of infants on neonatal intensive care units. Multidrug-resistant bacteria (MDR) that should be considered in empiric antibiotic therapy, bacteria that cause invasive infections and bacteria that may elicit epidemic …
Swallowing impairment in neurologic disorders: The role of videofluorographic swallowing study
2018
Patients with neurologic diseases almost inevitably develop various degrees of swallowing disorders during their life. Dysphagia is one of the main negative prognostic factors in this class of patients, leading to severe morbidity (i.e. aspiration pneumonia, dehydration, malnutrition, and life quality deterioration) and to a noticeable increase in public health spending. Videofluorographic swallowing study is considered the gold standard technique for swallowing impairment assessment. It is aimed at early identification of the risk of aspiration, definition of the kind and grade of dysphagia, and an indication to suspend oral nutrition and adopt other feeding strategies, and define when the…
Management of obstructive sleep apnea in Europe.
2011
Objectives: In Europe, the services provided for the investigation and management of obstructive sleep apnoea (OSA) varies from country to country. The aim of this questionnaire-based study was to investigate the current status of diagnostic pathways and therapeutic approaches applied in the treatment of OSA in Europe, qualification requirements of physicians involved in diagnosis and treatment of OSA, and reimbursement of these services. Methods: Two questionnaires were sent to 39 physicians in 22 countries in Europe. In order to standardize the responses, the questionnaire was accompanied by an example. Results: Sleep centers from 21 countries (38 physicians) participated. A broad consist…
Post-acute COVID-19 neurological syndrome: A new medical challenge
2021
In December 2019, in Wuhan (China), a highly pathogenic coronavirus, named SARS-CoV-2, dramatically emerged. This new virus, which causes severe pneumonia, is rapidly spreading around the world, hence it provoked the COVID-19 pandemic. This emergency launched by SARS-CoV-2 also had, and still has, devastating socio-economic aspects. Assessing the impact of COVID-19 on vulnerable groups of people is crucial for the adaptation of governments’ responses. Growing scientific evidence suggests that it is essential to keep the attention on people after acute SARS-CoV-2 infection; indeed, some clinical manifestations are frequently present even after recovery. There is consensus on the need to defi…
Technique and value of gas and pantopaque cisternography in the diagnosis of cerebello-pontine angle tumours
1971
The techniques of gas and Pantopaque cisternography are described, as well as the various advantages and disadventages of these methods. Patients without neurological signs in whom a small tumour is suspected in the region of the cerebellopontine angle should be examined with Pantopaque. The examination can be carried out as an outpatient procedure. If definite neurological signs are present, gas cisternography is preferable in order to demonstrate secondary displacements of the ventricular system as well as the tumour itself.
Placebo and Nocebo Effects Across Symptoms: From Pain to Fatigue, Dyspnea, Nausea, and Itch
2019
Contains fulltext : 208540.pdf (Publisher’s version ) (Open Access) Placebo and nocebo effects are, respectively, the helpful and harmful treatment effects that do not arise from active treatment components. These effects have thus far been researched most often in pain. It is not yet clear to what extent these findings from pain can be generalized to other somatic symptoms. This review investigates placebo and nocebo effects in four other highly prevalent symptoms: dyspnea, fatigue, nausea, and itch. The role of learning mechanisms (verbal suggestions, conditioning) in placebo and nocebo effects on various outcomes (self-reported, behavioral, and physiological) of these different somatic s…
Sleep apnea and its role in transportation safety
2017
Obstructive sleep apnea (OSA) is a main cause of excessive daytime sleepiness and increases the risk for driving accidents, which can be normalized by treatment with continuous positive airway pressure ventilation. Since it is estimated that OSA is not diagnosed in about 80% of cases, recognition of patients at risk for driving accidents is a problem from both medical and societal points of view. Strategies to screen and identify subjects at high risk for driving accidents are under study in order to improve safety on the road, especially for commercial drivers, who show a high prevalence of OSA.
Correlation between Polysomnographic Parameters and Tridimensional Changes in the Upper Airway of Obstructive Sleep Apnea Patients Treated with Mandi…
2021
Background. The effectiveness of mandibular advancement devices has been solidly demonstrated in the past. They are considered a valid alternative treatment to continuous positive airway pressure for patients with obstructive sleep apnea. Nevertheless, the relationship between polysomnographic parameters and the increase in the volume of the upper airway in patients with obstructive sleep apnea syndrome has not been clearly established so far. This study aimed to determine the impact of these oral appliances upon the volume of the airway after the device titration phase and correlate it with the degree of mandibular advancement and the improvement of polysomnographic parameters. Methods. Al…
Mepolizumab for eosinophilic chronic obstructive pulmonary disease
2017
BACKGROUNDPatients with chronic obstructive pulmonary disease (COPD) with an eosinophilic phenotype may benefit from treatment with mepolizumab, a monoclonal antibody directed against interleukin-5.METHODSWe performed two phase 3, randomized, placebo-controlled, double-blind, parallel-group trials comparing mepolizumab (100 mg in METREX, 100 or 300 mg in METREO) with placebo, given as a subcutaneous injection every 4 weeks for 52 weeks in patients with COPD who had a history of moderate or severe exacerbations while taking inhaled glucocorticoid-based triple maintenance therapy. In METREX, unselected patients in the modified intention-to-treat population with an eosinophilic phenotype were …
P343 Procalcitonin role in the management of lower respiratory tract infections in preschool children
2017
Introduction One of the major advantage of procalcitonin compared to other parameters is its highly and early increase in response to bacterial infection. The increased procalcitonin levels can be observed 3 to 6 hours after infectious challenge. It is a parameter that made a significant contribution to the clinical diagnosis, severity of infection and in the same time procalcitonin kinetics cand be used to assess the effectiveness of treatment. Methods A single- centre observational study consecutively enrolled 70 preschool children with lower respiratory tract infections who were hospitalised in Paediatric Clinic Hospital of Sibiu between January 2013 and January 2017. Procalcitonin, were…