Search results for "PNI"
showing 10 items of 159 documents
Kryzys parlamentaryzmu a majowy zamach stanu w aspekcie bezpieczeństwa narodowego
2017
Demokracja parlamentarna nie jest typem ustroju, który może sprawnie i stabilnie funkcjonować bez solidnych podstaw ekonomicznych i społecznych, ugruntowanej i opartej na kompromisie tradycji uprawiania polityki oraz postaw obywatelskich pośród polityków i społeczeństwa. Porzucenie demokracji czyjej częściowe ograniczenie, aczkolwiek usprawiedliwione ideą racji stanu w celu wzmocnienia szeroko pojętego bezpieczeństwa narodowego, nie musi okazać się właściwym lekarstwem na problemy, z jakimi boryka się państwo. Kryzys parlamentaryzmu i przewrót majowy, zamykają okres, w którym sejm stanowił organ ostatecznie decydujący o składzie i istnieniu kolejnych rządów. Formalną zmianę we wzajemnym usy…
Virtuālie asistenti procesu automatizācijā
2019
Darbā tiek aprakstīts kas ir virtuālie asistenti un dialoga sistēmas, kādas ir to komponentes un kā tās saistās savā starpā. Tiek aprakstīta robotizēta procesu automatizācijas tehnoloģija (RPA). Darba ietvaros ir izveidota unikāla “Dialogflow” dialoga sistēmas sasaiste ar RPA rīku “Blue Prism”, nodemonstrējot atvaļinājuma pieteikšanas procesa automatizāciju. Tehnoloģiju sasaistei papildus tika izmantots “Apigee Edge” starpniekserveris.
Būvmateriālu rūpniecības attīstība Latvijā: Bolderājas silikātķieģeļu rūpnīcas piemērs (1952-1959)
2018
Darbā tika pētīta Latvijas PSR būvmateriālu rūpniecības attīstība uz lielākā Latvijas būvmateriālu uzņēmuma – Bolderājas silikātķieģeļu rūpnīcas – piemēra, laika posmā no 1952. līdz 1959. gadam. Pētījuma mērķis bija, analizējot arhīva un citus pieejamus avotus, konstatēt šīs tautsaimniecības sfēras un konkrētā uzņēmuma darbības attīstības galvenās tendences dotajā laika posmā. Pētījuma gaitā tika izpētīta Latvijas PSR būvmateriālu rūpniecības attīstība, īpašu uzmanību pievēršot izvēlētai rūpnīcai: izpētot tās struktūru, ražošanas procesu un produkciju, tās finansiālus radītājus, kā arī šīs rūpnīcas ražošanas procesā iesaistītā darbaspēka faktoru – tā darba un dzīves apstākļus. Kritiski izvē…
Measurement of brain tissue pressure in cold induced cerebral oedema.
1973
Experiments were performed in order to evaluate the concept that brain oedema is associated with an increase in local interstitial fluid pressure. Assuming that the pressure measured by the cotton wick technique represents the hydrostatic interstitial fluid pressure, the tissue pressure was recorded with pressure transducers in the white matter adjacent and remote to a local cold injury, in the opposite hemisphere, and in the cisterna magna. In 9 cats during steady-state conditions mean tissue pressures between 1.20±0.30 mm Hg and 2.33±0.80 mm Hg were found, as compared to a mean CSF pressure of 5.17±0.82 mm Hg. The tissue pressure was found to increase significantly adjacent to the lesion …
Differential contribution of dead space ventilation and low arterial pCO2 to exercise hyperpnea in patients with chronic heart failure secondary to i…
2003
In chronic heart failure (CHF), the abnormally large ventilatory response to exercise (VE/VCO(2) slope) has 2 conceptual elements: the requirement of restraining arterial partial pressure of carbon dioxide (pCO(2)) from increasing (because of an increased ratio between increased physiologic dead space and tidal volume [VD/VT]) and the depression of arterial pCO(2) by further increased ventilation, which necessarily implies an important non-carbon dioxide stimulus to ventilation. We aimed to assess the contribution of these 2 factors in determining the elevated VE/VCO(2) slope in CHF. Thirty patients with CHF underwent cardiopulmonary exercise testing (age 65 +/- 11 years, left ventricular e…
Role of IP3 Receptors in Shaping the Carotid Chemoreceptor Response to Hypoxia but not to Hypercapnia in the Rat Carotid Body: An Evidence Review
2021
This article addresses the disparity in the transduction pathways for hypoxic and hypercapnic stimuli in carotid body glomus cells. We investigated and reviewed the experimental evidence showing that the response to hypoxia, but not to hypercapnia, is mediated by 1,4,5-inositol triphosphate receptors (IP3R/s) regulating the intracellular calcium content [Ca2+]c in glomus cells. The rationale was based on the past observations that inhibition of oxidative phosphorylation leads to the explicit inhibition of the hypoxic chemoreflex. [Ca2+]c changes were measured using cellular Ca2+-sensitive fluorescent probes, and carotid sinus nerve (CSN) sensory discharge was recorded with bipolar electrode…
Description of the response of a new multi-parametric brain sensor to physiological and pathophysiological challenges in the cortex of juvenile pigs
2014
AIM Monitoring of intracranial pressure (ICP), local cerebral blood flow (CBF) and oxygen is part of modern intensive critical care medicine. Preclinical evaluation of newly developed catheters that should monitor several parameters simultaneously is reported poorly in the literature. The goal of our study was (1) to evaluate a new multi-parametric sensor in brain tissue and (2) to establish a testing protocol using pathophysiological challenges that target measured parameters of the sensor and autoregulatory boundaries and could be used as preclinical standard protocol in future studies. MATERIAL AND METHODS We describe data from 12 new multi-parametric brain sensors (MPBS) that were impla…
ChemInform Abstract: Weak Interactions Between Trivalent Pnictogen Centers: Computational Analysis of Bonding in Dimers X3E···EX3(E: Pnictogen, X: Ha…
2009
The nature of weak interactions in dimers X3E···EX3 (E = N−Bi, X = F−I) was investigated by wave function and density functional theory (DFT)-based methods. Out of the 20 systems studied, 10 are found to be bound at the CP-MP2 and LMP2 levels of theory. Detailed partition of the interaction energy into different components revealed that dispersion is the primary force holding the dimers together but there also exists an important ionic component whose contribution increases with increasing halogen size. As expected, standard density functionals fail to describe bonding in the studied systems. However, the performance of DFT methods can be easily improved via empirical dispersion correction …
High-flow nasal therapy versus noninvasive ventilation in COPD patients with mild-to-moderate hypercapnic acute respiratory failure: study protocol f…
2019
Background Noninvasive ventilation (NIV) is indicated to treat respiratory acidosis due to exacerbation of chronic obstructive pulmonary disease (COPD). Recent nonrandomized studies also demonstrated some physiological effects of high-flow nasal therapy (HFNT) in COPD patients. We designed a prospective, unblinded, multicenter, randomized controlled trial to assess the noninferiority of HFNT compared to NIV with respect to the reduction of arterial partial pressure of carbon dioxide (PaCO2) in patients with hypercapnic acute respiratory failure with mild-to-moderate respiratory acidosis. Methods We will enroll adult patients with acute hypercapnic respiratory failure, as defined by arterial…
Valsts probācijas dienesta funkcija- izlīguma organizēšana un vadīšana kriminālprocesā ar starpnieka palīdzību
2015
Noziedzīga nodarījuma rezultātā likumpārkāpējs ir radījis kaitējumu noteiktai personai – cietušajam. Sabiedrībā valda uzskats, ka likumpārkāpēju var sodīt tikai bargs sods, bet ne vienmēr tas ir labākais risinājums. Bieži vien labs risinājums ir izlīgums, kas noslēgts starp cietušo un likumpārkāpēju. Izlīguma rezultātā likumpārkāpējs atzīst savu vainu, bet cietušais gūst gan morālu, gan finansiālu mierinājumu un atzīst, ka pēc izlīguma noslēgšanas viņam nav prasību pret likumpārkāpēju. Izlīgumā iesaistītās puses ar starpnieka palīdzību sarunu ceļā risina radušos konfliktu. Likumpārkāpējam bieži var būt pat smagāk satikt un uzklausīt cietušo klātienē, nekā izciest tiesas piespriesto sodu, tā…