Search results for "POA"

Ipoacusia neurosensoriale causata da scoppio di petardo. Aspetti medico-legali

2013

Gli Autori illustrano un caso di ipoacusia neurosensoriale permanente rilevata all’orecchio di sinistra con un deficit uditivo pantonale pari a 70 dB. La lesione è stata determinata dallo scoppio di un petardo, lanciato in vicinanza della persona lesa. Vengono valutati i risvolti medico-legali in ambito penale e civile. Per quanto concerne la sfera penalistica l’ipotesi di reato è quella di lesione personale grave, in ragione dell’indebolimento permanente della funzione uditiva; relativamente al contesto civilistico, si pone particolare attenzione alla questione inerente al risarcimento cui il soggetto danneggiante è obbligato, considerando in particolar modo gli effetti che la lesione ha d…

Efficacy of three drugs for protecting against gentamicin-induced hair cell and hearing losses

2012

BACKGROUND AND PURPOSEExposure to an ototoxic level of an aminoglycoside can result in hearing loss. In this we study investigated the otoprotective efficacy of dexamethasone (DXM), melatonin (MLT) and tacrolimus (TCR) in gentamicin (GM)-treated animals and cultures.EXPERIMENTAL APPROACHWistar rats were divided into controls (treated with saline); exposed to GM only (GM); and three GM-exposed groups treated with either DXM, MLT or TCR. Auditory function and cochlear surface preparations were studied. In vitro studies of oxidative stress, pro-inflammatory cytokine mRNA levels, the MAPK pathway and caspase-3 activation were performed in organ of Corti explants from 3-day-old rats.KEY RESULTSD…

Al di là del sintomo. Il gruppo psicodinamico nelle dipendenze

2012

I Disturbi da Uso di Sostanze (DUS) e i Disturbi del Comportamento Alimentare (DCA) presentano delle caratteristiche comuni. Essi infatti si manifestano attraverso un attacco al corpo, presentano un’insorgenza in età adolescenziale o tardo adolescenziale e una prevalenza associata rispettivamente al genere maschile e femminile. In una prospettiva psicodinamica, ciò che soprattutto accomuna i DUS e i DCA (insieme ai disturbi psicosomatici) è il fatto di poter essere considerati dei disturbi di secondo livello, dei quadri sintomatologici di copertura rispetto ad una sofferenza psichica sottostante. In questo senso possono essere considerate delle modalità di auto-terapia e autoregolazione emo…

CLA, “new nutrients”?

2005

International audience; Conjugated linoleic acid (CLA) refers to a class of positional and geometric dienoic isomers of linoleic acid. Chronic dietary supplementation with commercial isomeric mixtures sold as dietary supplements leads to a drop in fat mass in various species. The t10,c12-CLA isomer is responsible for this antiobesity effect.The reduction of fat mass is especially dramatic in the mouse, in which it is associated with a severe hyperinsulinemia, an insulin resistance and a massive liver steatosis. The origin of these adverse side effects and the putative chronology of events leading to CLA-mediated lipoatrophic syndrome are presented and discussed in this review. In Human, the…

Diuron mobility through vineyard soils contaminated with copper

2005

International audience; The herbicide diuron is frequently applied to vineyard soils in Burgundy, along with repeated treatments with Bordeaux mixture (a blend of copper sulfate and calcium hydroxide) that result in elevated copper concentrations. Cu could in principle affect the fate and transport of diuron or its metabolites in the soil either directly by complexation or indirectly by altering the populations or activity of microbes involved in their degradation. To assess the effect of high Cu concentrations on diuron transport, an experiment was designed with ten undisturbed columns of calcareous and acidic soils contaminated with 17–509 mg kg−1 total Cu (field-applied). Grass was plant…

Le ricerche sullo psichismo mafioso

2011

Mafia e psiche

2011

Efficacy of sublingual immunotherapy with grass allergens for seasonal allergic rhinitis: A systematic review and meta-analysis

2010

Background The benefit of sublingual immunotherapy (SLIT) with grass allergens for seasonal allergic rhinitis has been extensively studied, but data on efficacy are still equivocal. Objective To assess the effectiveness of SLIT with grass allergens in the reduction of symptoms and medication in patients with seasonal allergic rhinitis to grass pollen. Methods Computerized bibliographic searches of MEDLINE (1995-2010) were supplemented by hand searches of reference lists. Studies were included if they were double-blind randomized controlled trials (RCTs) comparing SLIT to placebo and if they included patients with history of allergy to grass pollen treated with natural grass pollen extracts.…

The rational use of albumin in patients with cirrhosis and ascites

2004

Abstract Background. Ascites is one of the most frequent severe complications in patients with liver cirrhosis. The treatment of this chronic disease usually requires the prolonged use of albumin, frequently continued even after patients’ discharge from the hospital. Aims. Aim of the study was to define a consensus among Italian physicians with regard to the use of albumin in patients with decompensated cirrhosis and ascites. Methods. The study adopted the Delphi technique to conduct the consensus activities. All controversial issues related to the use of albumin were identified by the experts’ board and proposed to the 68 participating hepatology centres through two subsequent questionnair…

Efavirenz induces alterations in lipid metabolism through AMPK activation

2008

Summary of results EFV produced an immediate reduction of mitochondrialfunction, evident by the significant and dose-dependentinhibition of mitochondrial O2 consumption and thedecrease of intracellular ATP and Δψm. This metabolicstress promoted the activation of AMPK, triggering severalof its signalling pathways, as EFV induced an increment inCD36 mRNA expression and in intracellular lipid content,which could have been a result of the formation of lipiddroplets. This intracellular lipid increase was not presentin cells treated with Compound C, which points to a keyrole for AMPK in these mechanisms. Conclusion Given that EFV treatment is usually prolonged, thesemechanisms may effect the gene…