Search results for "POD"

Influencia de la agenesia dental en el desarrollo de la dentición

2016

La agenesia dental describe la ausencia de desarrollo de al menos un diente. Estudios recientes sugieren la relación entre determinados patrones de agenesia y retraso en el desarrollo dental, debido a algunos genes específicos. Existen diferentes métodos para evaluar la edad de desarrollo, por ello es difícil comparar en la bibliografía los estudios que relacionan desarrollo dental con agenesia, así mismo, existen diferentes variantes que dificultan la comparación de los diferentes estudios. Una mejora en la comprensión del desarrollo dental en estos pacientes es importante para la planificación del tratamiento de ortodoncia y proporcionar una referencia para evaluar la edad específica para…

BAG3 and friends: co-chaperones in selective autophagy during aging and disease.

2011

There is a reciprocal change in the expression of two members of the BAG (Bcl-2-associated athanogen) family, BAG1 and BAG3, during cellular aging and under acute stress ("BAG1-BAG3-switch"). BAG3 was recently described as a mediator of a novel macroautophagy pathway that uses the specificity of heat shock protein 70 (HSP70) to misfolded proteins and also involves other protein partners, such as HSPB8. Also crucial for induction and execution of autophagy are sequestosome-1/p62 (SQSTM1/p62) and LC3, an autophagosome-associated protein. In this novel pathway, BAG3 mediates the targeting and transport of degradation-prone substrates into aggresomes via the microtubule-motor dynein. Interestin…

Seasonal changes in host phenotype manipulation by an acanthocephalan: time to be transmitted?

2009

Parasitology, 136 (2)

Extracellular Domains of the Bradykinin B2 Receptor Involved in Ligand Binding and Agonist Sensing Defined by Anti-peptide Antibodies

1996

Many of the physiological functions of bradykinin are mediated via the B2 receptor. Little is known about binding sites for bradykinin on the receptor. Therefore, antisera against peptides derived from the putative extracellular domains of the B2 receptor were raised. The antibodies strongly reacted with their corresponding antigens and cross-reacted both with the denatured and the native B2 receptor. Affinity-purified antibodies to the various extracellular domains were used to probe the contact sites between the receptor and its agonist, bradykinin or its antagonist HOE140. Antibodies to extracellular domain 3 (second loop) efficiently interfered, in a concentration-dependent manner, with…

Subtype-Specific Desensitization of Human Endothelin ETA and ETB Receptors Reflects Differential Receptor Phosphorylation

1997

Endothelins regulate blood pressure in mammals through G protein-coupled receptors. Two receptor subtypes, ETA and ETB, exist which differ by their agonist profiles. Here we show subtype-specific differences in the inactivation of these endothelin receptors. Using a modified inositol phosphate accumulation assay, we found that stimulation of ETA by endothelin-1 results in sustained activation of the subtype, retaining >30% of its initial activity even 20 min after agonist administration, whereas the ETB rapidly deactivated after agonist stimulation, losing >80% of its initial activity within 5 min after endothelin application. The discrepancy in receptor inactivation is reflected by subtype…

Shared midgut binding sites for Cry1A.105, Cry1Aa, Cry1Ab, Cry1Ac and Cry1Fa proteins from Bacillus thuringiensis in two important corn pests, Ostrin…

2013

First generation of insect-protected transgenic corn (Bt-corn) was based on the expression of Cry1Ab or Cry1Fa proteins. Currently, the trend is the combination of two or more genes expressing proteins that bind to different targets. In addition to broadening the spectrum of action, this strategy helps to delay the evolution of resistance in exposed insect populations. One of such examples is the combination of Cry1A.105 with Cry1Fa and Cry2Ab to control O. nubilalis and S. frugiperda. Cry1A.105 is a chimeric protein with domains I and II and the C-terminal half of the protein from Cry1Ac, and domain III almost identical to Cry1Fa. The aim of the present study was to determine whether the c…

CAN HELICICULTURE ACT AS A TOOL FOR EDIBLE LAND SNAILS’ NATURAL POPULATIONS’ MANAGEMENT IN ROMANIA?

2013

ABSTRACT Edible land snails are intensively exploited and the management of natural populations is a complex issue due the variety of factors involved. Two species of the genus Helix are present in our country, Helix pomatia and Helix lucorum, both of them collected since 1956. Although current legislation regulates the exploited amount and the dimension of collected snails, the exploitable amount is not assessed using appropriate ecological studies. The farming of edible snails has evolved in Romania especially during the period 2004-2008, the first farms being financed by the SAPARD Project. The inappropriate documentation on the matter of snail farming had lead to a quick failure of this…

Data from: Effects of undergrowth removal and edge proximity on ground beetles and vascular plants in urban boreal forests

2019

Urban forests are regularly managed for human safety and aesthetic reasons, but they are crucial habitat for many species. Removals of undergrowth occur commonly in these forests, yet the ecological consequences of these operations are poorly understood. We sampled ground beetles (Coleoptera, Carabidae) and vascular plants along 20-m edge gradients in Finnish urban forests, in five stands treated 0.5−2.5 years earlier with undergrowth removal and in five untreated stands. We hypothesized that undergrowth removal and edge proximity would benefit opportunistic and open-habitat species, whereas shady-habitat species would be affected negatively. (1) Regarding carabids, diversity and evenness i…

Recio Morales, Oscar: Alejandro O'Reilly, inspector general. Poder militar, familia y territorio en el reinado de Carlos III

2021

Logika algorytmów w świecie pracy ery technologicznej - nowe możliwości i nowe ograniczenia

2022

Uprawnienia kierownicze pracodawcy wynikające z przepisów prawa pracy są innej natury niż te kształtowane przez technologię, lokują one działanie kierownictwa pracodawcy w zupełnie innym obszarze niż technologia — w relacjach międzyludzkich, a nie w danych, w poleceniach, a nie w sygnałach, w odnoszeniu się do sposobów bycia jednostki, a nie do sprzężeń zwrotnych, do jej sumienności i staranności, a nie do nastawiania jej na wykorzystywanie. Kierownictwo technologiczne ma inne środki wyrazu, inną metodykę działania, inną skalę przymusu i porządku, jest inaczej zabezpieczane, nie zna granic, które stawia się kierownictwu normatywnemu. Technologia pozwala na zmianę paradygmatu kierownictwa dz…