Search results for "POINT"

Disagreement, Points of View, and Truth-Relativism

2022

AbstractTruth-relativism is the claim that the truth of statements is dependent on the context in which they are made. In this article, truth-relativism is considered as a way to explain disagreements. Viewpoint relativism, a recent version of truth-relativism, is introduced as a useful framework to analyse how truth-relativism approaches disagreements. Viewpoint relativism is based on contextual semantics and the logic of viewpoint, which is a two-dimensional modal logic. In viewpoint relativism, the central concept is a point of view in relation to which truth claims are evaluated. Viewpoint relativism is compared to the truth-relativism of Peter Lasersohn and John MacFarlane. Finally, tr…

CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreati…

2021

Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the molecular mechanisms of pathogenesis underlying CVB3-induced acute pancreatitis have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation and exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, and confocal microscopy, we show that Menage a trois 1 (MAT1), a subunit of the Cdk-Activating Kinase (CAK) complex involved in cell proliferation and transcription, is a novel interaction protein with CVB3 VP1. Moreover, CVB3 VP1 inhibited MAT…

Molecular Characterization of a Variant of Bacillus anthracis-Specific Phage AP50 with Improved Bacteriolytic Activity▿ †

2008

ABSTRACT The genome sequence of a Bacillus anthracis -specific clear plaque mutant phage, AP50c, contains 31 open reading frames spanning 14,398 bp, has two mutations compared to wild-type AP50t, and has a colinear genome architecture highly similar to that of gram-positive Tectiviridae phages. Spontaneous AP50c-resistant B. anthracis mutants exhibit a mucoid colony phenotype.

Relationship between volume and energy of vector fields

2001

Abstract A unified study of energy and volume functionals is presented here by determining the critical points of a functional that extends simultaneously energy and volume and that is defined on the product of the manifold of smooth maps C∞(M,N) times the manifold M of riemannian metrics on M. The restriction of this functional to different submanifolds of the space of vector fields X (M)× M is also considered, and used to study several functionals generalizing volume and energy or total bending of vector fields

Anticipatory Postural Adjustments and kinematic arm features when postural stability is manipulated

2018

International audience; Beyond the classical paradigm that presents the Anticipatory Postural Adjustments (APAs) as a manner to create forces that counteract disturbances arising from the moving segment during a pointing task, there is a controversial discussion about the role APAs to facilitate the movement and perform a task accurately. In addition, arm kinematics features are classically used to infer the content of motor planning for the execution and the control of arm movements, The present study aimed to disentangle the conflicting role of APAs during an arm-pointing task in which the subjects reach a central diode that suddenly turns on, while their postural stability was manipulate…

An analytical-numerical study of dynamic stability of an axially moving elastic web

2015

This paper is devoted to a dynamic stability analysis of an axially moving elastic web, modelled as a panel (a plate undergoing cylindrical deformation). The results are directly applicable also to the travelling beam. In accordance with the dynamic approach of stability analysis, the problem of harmonic vi- brations is investigated via the study of the dependences of the system’s nat- ural frequencies on the problem parameters. Analytical implicit expressions for the solution curves, with respect to problem parameters, are derived for ranges of the parameter space where the natural frequencies are real-valued, corresponding to stable vibrations. Both axially tensioned and non-tensioned tra…

On the convergence of zero-point vibrational corrections to nuclear shieldings and shielding anisotropies towards the complete basis set limit in wat…

2016

The method and basis set dependence of zero-point vibrational corrections (ZPVCs) to nuclear magnetic resonance shielding constants and anisotropies has been investigated using water as a test system. A systematic comparison has been made using the Hartree–Fock, second-order Møller–Plesset perturbation theory (MP2), coupled cluster singles and doubles (CCSD), coupled cluster singles and doubles with perturbative triples corrections (CCSD(T)) and Kohn–Sham density functional theory with the B3LYP exchange-correlation functional methods in combination with the second-order vibrational perturbation theory (VPT2) approach for the vibrational corrections. As basis sets, the correlation consisten…

Kinetics of phase separation in thin films: Lattice versus continuum models for solid binary mixtures

2008

A description of phase separation kinetics for solid binary (A,B) mixtures in thin film geometry based on the Kawasaki spin-exchange kinetic Ising model is presented in a discrete lattice molecular field formulation. It is shown that the model describes the interplay of wetting layer formation and lateral phase separation, which leads to a characteristic domain size $\ell(t)$ in the directions parallel to the confining walls that grows according to the Lifshitz-Slyozov $t^{1/3}$ law with time $t$ after the quench. Near the critical point of the model, the description is shown to be equivalent to the standard treatments based on Ginzburg-Landau models. Unlike the latter, the present treatmen…

Toxicity of retene and pyrene on fish at different light conditions

2011

Univariate and multivariate properties of wind velocity time series

2009

We analyze the time series of hourly average wind speeds measured at 29 different stations located in Sicily, a region with a complex morphology. The investigation, performed from the univariate as well as the multivariate point of view, evidences that the statistical properties of wind at the single sites have features that are not reproduced by standard models and, thus, require specific modeling. Moreover, the synchronous evolution of wind velocity presents a cluster structure, obtained with different algorithms, that persists in the standard deviation too.