Search results for "POPULATION GENETICS"

showing 10 items of 265 documents

Genetic and Ecotypic Differentiation in a Californian Plant Polyploid Complex (Grindelia, Asteraceae)

2014

Studies of ecotypic differentiation in the California Floristic Province have contributed greatly to plant evolutionary biology since the pioneering work of Clausen, Keck, and Hiesey. The extent of gene flow and genetic differentiation across interfertile ecotypes that span major habitats in the California Floristic Province is understudied, however, and is important for understanding the prospects for local adaptation to evolve or persist in the face of potential gene flow across populations in different ecological settings. We used microsatellite data to examine local differentiation in one of these lineages, the Pacific Coast polyploid complex of the plant genus Grindelia (Asteraceae). W…

Evolutionary GeneticsMarshPlant EvolutionSpeciationlcsh:MedicinePlant ScienceCaliforniaGene flowPloidyMolecular SystematicsNatural Selectionlcsh:ScienceFlowering Plantseducation.field_of_studyMultidisciplinarygeography.geographical_feature_categoryGeographyEcotypeEcologyfood and beveragesPolyploid complexPlantsBiological EvolutionHabitatResearch ArticleGene FlowEvolutionary ProcessesGrindeliaGenotypeGeneral Science & TechnologyPopulationParallel EvolutionBiologyPolyploidyGrindeliaEvolutionary Adaptationparasitic diseasesGeneticsEvolutionary SystematicseducationHybridizationTaxonomyLocal adaptationEcotypeEvolutionary BiologygeographyPopulation Biologylcsh:ROrganismsBiology and Life SciencesGeobotanyPlant Taxonomybiology.organism_classificationOrganismal EvolutionGenetic Locilcsh:QPopulation GeneticsMicrosatellite RepeatsPLoS ONE
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From molecular genetics to phylodynamics: evolutionary relevance of mutation rates across viruses.

2012

Although evolution is a multifactorial process, theory posits that the speed of molecular evolution should be directly determined by the rate at which spontaneous mutations appear. To what extent these two biochemical and population-scale processes are related in nature, however, is largely unknown. Viruses are an ideal system for addressing this question because their evolution is fast enough to be observed in real time, and experimentally-determined mutation rates are abundant. This article provides statistically supported evidence that the mutation rate determines molecular evolution across all types of viruses. Properties of the viral genome such as its size and chemical composition are…

Evolutionary Geneticslcsh:Immunologic diseases. AllergyMutation rateGenome evolutionImmunologyGenome ViralBiologyGenomeMicrobiologyEvolution Molecular03 medical and health sciencesMutation RateMolecular evolutionPhylogeneticsVirologyGeneticsMolecular BiologyBiologylcsh:QH301-705.5Phylogeny030304 developmental biologyGenetics0303 health sciencesEvolutionary BiologyModels Genetic030306 microbiologyMutagenesisMicrobial MutationBiological EvolutionViral phylodynamicslcsh:Biology (General)Viral evolutionVirusesParasitologylcsh:RC581-607Population GeneticsResearch ArticlePLoS Pathogens
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Reconstruction of the evolutionary history of Saccharomyces cerevisiae x S. kudriavzevii hybrids based on multilocus sequence analysis.

2012

In recent years, interspecific hybridization and introgression are increasingly recognized as significant events in the evolution of Saccharomyces yeasts. These mechanisms have probably been involved in the origin of novel yeast genotypes and phenotypes, which in due course were to colonize and predominate in the new fermentative environments created by human manipulation. The particular conditions in which hybrids arose are still unknown, as well as the number of possible hybridization events that generated the whole set of natural hybrids described in the literature during recent years. In this study, we could infer at least six different hybridization events that originated a set of 26 S…

Evolutionary Geneticslcsh:MedicineYeast and Fungal ModelsWineSaccharomycesGenomeSouth AfricaNatural SelectionFungal EvolutionDNA FungalMycological Typing Techniqueslcsh:ScienceGenome EvolutionPhylogenyRecombination GeneticGeneticsMultidisciplinarybiologyfood and beveragesGenomicsBiological EvolutionEuropePhylogeographyPloidyResearch ArticleGenome evolutionEvolutionary ProcessesGenotypeGenes FungalIntrogressionGenomicsMycologySaccharomyces cerevisiaeMicrobiologySaccharomycesModel OrganismsPhylogeneticsGeneticsHumansAdaptationBiologyHybridizationHybridEvolutionary BiologyPloidiesChimeralcsh:RComparative GenomicsSouth Americabiology.organism_classificationYeastGenetic Polymorphismlcsh:QPopulation GeneticsMultilocus Sequence TypingPLoS ONE
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Forward and backward diffusion approximations for haploid exchangeable population models

2001

Abstract The class of haploid population models with non-overlapping generations and fixed population size N is considered such that the family sizes ν1,…,νN within a generation are exchangeable random variables. A criterion for weak convergence in the Skorohod sense is established for a properly time- and space-scaled process counting the number of descendants forward in time. The generator A of the limit process X is constructed using the joint moments of the offspring variables ν1,…,νN. In particular, the Wright–Fisher diffusion with generator Af(x)= 1 2 x(1−x)f″(x) appears in the limit as the population size N tends to infinity if and only if the condition lim N→∞ E((ν 1 −1) 3 )/(N Var …

Exchangeable random variablesStatistics and ProbabilityDualityPopulation geneticsCoalescent theoryDiffusion approximationModelling and SimulationQuantitative Biology::Populations and EvolutionNeutralityWright–Fisher diffusionHille–Yosida theoremWeak convergenceMathematicsWeak convergenceApplied MathematicsMathematical analysisHeavy traffic approximationCommutative diagramHille–Yosida theoremPopulation modelDiffusion processModeling and SimulationAncestorsDescendantsExchangeabilityCoalescentStochastic Processes and their Applications
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Polymorphisms in ABC transporter genes and concentrations of mercury in newborns - Evidence from two Mediterranean birth cohorts

2014

Background: The genetic background may influence methylmercury (MeHg) metabolism and neurotoxicity. ATP binding cassette (ABC) transporters actively transport various xenobiotics across biological membranes. Objective: To investigate the role of ABC polymorphisms as modifiers of prenatal exposure to MeHg. Methods: The study population consisted of participants (n = 1651) in two birth cohorts, one in Italy and Greece (PHIME) and the other in Spain (INMA). Women were recruited during pregnancy in Italy and Spain, and during the perinatal period in Greece. Total mercury concentrations were measured in cord blood samples by atomic absorption spectrometry. Maternal fish intake during pregnancy w…

Fetus -- CreixementMaternal HealthEmbaràsEnvironmental Health and Occupational Healthlcsh:MedicinePhysiologyATP-binding cassette transporterSangToxicologyHeavy MetalsBiochemistryCohort Studieschemistry.chemical_compoundGene FrequencyPregnancySurveys and QuestionnairesGenotypeMedicine and Health SciencesToxinslcsh:ScienceMethylmercuryGeneticsMultidisciplinaryGreeceObstetrics and GynecologyFetal BloodMultidrug Resistance-Associated Protein 23. Good healthChemistryItalyMaternal ExposureResearch DesignCord bloodBlood ChemistryPhysical SciencesPopulation studyFemaleEpigeneticsResearch ArticleAdultNeurotoxicologyPollutantsGenotypeClinical Research DesignToxic AgentsSingle-nucleotide polymorphismBiologyResearch and Analysis MethodsYoung AdultFish ProductsGeneticsmedicineHumansEnvironmental ChemistryAllele frequencyNutritionEvolutionary BiologyPregnancyPolymorphism GeneticPopulation Biologylcsh:RInfant NewbornBiology and Life SciencesComputational BiologyHuman GeneticsMercurymedicine.diseasechemistrySpainGenetic PolymorphismWomen's HealthATP-Binding Cassette Transporterslcsh:QPopulation Genetics
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Evolution of Leaf Morphogenesis: Evidence from Developmental and Phylogenetic Data in Papaveraceae

1999

Variation of leaf morphology in Papaveraceae s.l. (including Fumariaceae and Pteridophyllum) has previously been shown to be related to developmental differences in the direction of segmentation and in blade‐petiole differentiation. Based on ontogenetic comparisons, we here distinguish polyternate, acropetal, basipetal‐pedate, basipetal‐pinnate, and divergent modes of dissection. In addition, undissected leaves occur in some taxa. Dissection modes can be grouped in two classes on the basis of blade‐petiole differentiation. Mapping of these morphogenetic traits on an independently obtained phylogenetic reconstruction reveals a high degree of homoplasy, indicating multiple evolutionary parall…

Fixation (population genetics)TaxonPhylogenetic treeOntogenyBotanyPapaveraceaeLeaf morphogenesisPlant ScienceBiologyPteridophyllumbiology.organism_classificationCladeEcology Evolution Behavior and SystematicsInternational Journal of Plant Sciences
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Linking seed dispersal and genetic structure of trees: a biogeographical approach

2009

Aim  Natural and human-induced differences in frugivore assemblages can influence the seed dispersal distances of trees. An important issue in seed dispersal systems is to understand whether differences in seed dispersal distances also affect the genetic structure of mature trees. One possible approach to test for a relationship between seed dispersal and the genetic structure of mature trees is to compare the genetic structure of two closely related tree species between two biogeographical regions that differ in frugivore assemblages and seed dispersal distances. Previous studies on two Commiphora species revealed that Commiphora guillauminii in Madagascar has a much lower seed dispersal d…

FrugivoreEcologyPollinationEcologySeed dispersalparasitic diseasesGenetic structureGenetic variationSpatial ecologyPopulation geneticsBiological dispersalBiologyEcology Evolution Behavior and SystematicsJournal of Biogeography
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Allozyme electrophoresis: its application to rotifers

1998

Allozyme electrophoresis is a well established technique for revealing genetic variation that has given useful results in a wide range of organisms. However, in rotifers it has been applied scarcely and only in a few species. In this paper the methods of acetate allozyme electrophoresis are introduced, including laboratory setup, equipment and staining recipes that have been successfully applied to brachionid rotifers. In addition, the literature published on allozyme electrophoresis in rotifers is reviewed and the main results and future prospects of the technique are discussed. We conclude that, despite the onset of DNA techniques, allozyme electrophoresis is promising and can yield impor…

Gel electrophoresisSystematicsGeneticsbiologyRange (biology)Genetic variationZoologyPopulation geneticsRotiferGenetic variabilityGel electrophoresis of proteinsbiology.organism_classification
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Absence of spatial genetic structure in common dentex (Dentex dentex Linnaeus, 1758) in the Mediterranean Sea as evidenced by nuclear and mitochondri…

2018

International audience; The common dentex, Dentex dentex, is a fish species which inhabits marine environments in the Mediterranean and Northeast Atlantic regions. This is an important species from an ecological, economic and conservation perspective, however critical information on its population genetic structure is lacking. Most samples were obtained from the Mediterranean Sea (17 sites) with an emphasis around Corsica (5 sites), plus one Atlantic Ocean site. This provided an opportunity to examine genetic structuring at local and broader scales to provide science based data for the management of fishing stocks in the region. Two mitochondrial regions were examined (D-loop and COI) along…

Gene Flow0106 biological sciences0301 basic medicinePopulation geneticsPopulationZoologyPopulation geneticslcsh:MedicineDNA Mitochondrial010603 evolutionary biology01 natural sciencesMarine fish03 medical and health sciencesMediterranean seaGene FrequencyMediterranean SeaAnimals14. Life underwatereducationlcsh:ScienceAtlantic OceanAllelesPhylogenyIsolation by distanceCell NucleusPanmixiaeducation.field_of_studyMultidisciplinary[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]biologylcsh:RGenetic VariationBayes TheoremDentex dentexbiology.organism_classificationMitochondrial DNAMitochondriaPerciformesDentex dentex D-loop COI microsatellite loci Mediterranean Sea Atlantic Ocean.Polymerase chain reactionPhylogeographyPhylogeography[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal geneticsGenetics Population030104 developmental biologyHaplotypesGenetic structurelcsh:QMicrosatellite RepeatsPLoS ONE
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Ancient DNA reveals prehistoric gene-flow from Siberia in the complex human population history of North East Europe.

2013

North East Europe harbors a high diversity of cultures and languages, suggesting a complex genetic history. Archaeological, anthropological, and genetic research has revealed a series of influences from Western and Eastern Eurasia in the past. While genetic data from modern-day populations is commonly used to make inferences about their origins and past migrations, ancient DNA provides a powerful test of such hypotheses by giving a snapshot of the past genetic diversity. In order to better understand the dynamics that have shaped the gene pool of North East Europeans, we generated and analyzed 34 mitochondrial genotypes from the skeletal remains of three archaeological sites in northwest Ru…

Gene Flow0106 biological sciencesCancer Researchlcsh:QH426-470GenotypePopulation DynamicsPopulationPopulation ModelingScandinavian and Nordic CountriesBiologySocial and Behavioral SciencesDNA Mitochondrial010603 evolutionary biology01 natural sciencesWhite PeopleHaplogroupRussiaCoalescent theory03 medical and health sciencesGeneticsHumanseducationBiologyMolecular BiologyGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologyEvolutionary Biology0303 health scienceseducation.field_of_studyGenetic diversityPopulation BiologyGenetic VariationPaleogeneticsEuropeSiberialcsh:GeneticsBiological AnthropologyGenetics PopulationAncient DNAArchaeologyHaplotypesEvolutionary biologyAnthropologyGenome MitochondrialGene poolPopulation GeneticsResearch ArticleHuman mitochondrial DNA haplogroup
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