Search results for "POPULATION-STRUCTURE"

showing 8 items of 8 documents

Microevolution of bank voles (Myodes glareolus) at neutral and immune-related genes during multiannual dynamic cycles: consequences for Puumala hanta…

2017

ABSTRACTUnderstanding how host dynamics, including variations of population size and dispersal, may affect the epidemiology of infectious diseases through ecological and evolutionary processes is an active research area. Here we focus on a bank vole (Myodes glareolus) metapopulation surveyed in Finland between 2005 and 2009. Bank vole is the reservoir of Puumala hantavirus (PUUV), the agent of nephropathia epidemica (NE, a mild form of hemorrhagic fever with renal symptom) in humans.M glareoluspopulations experience multiannual density fluctuations that may influence the level of genetic diversity maintained in bank voles, PUUV prevalence and NE occurrence. We examine bank vole metapopulati…

0301 basic medicineMaleMyxovirus Resistance Proteins0106 biological sciencesSELECTIONPopulation geneticsPopulation DynamicsGene ExpressionPopulation geneticsNATURAL-POPULATIONPuumala virus01 natural sciencesRodent DiseasesNephropathia epidemicaFinlandGeneticsMolecular Epidemiology0303 health scienceseducation.field_of_studyRodentArvicolinaeMicroevolutionBiological EvolutionBank voleInfectious DiseasesMHC DIVERSITYHemorrhagic Fever with Renal SyndromeHost-Pathogen Interactions[SDV.IMM]Life Sciences [q-bio]/ImmunologyFemaleDisease SusceptibilityDensity fluctuationsMicrobiology (medical)Gene FlowPopulationMetapopulationBiologyMicrobiology010603 evolutionary biology03 medical and health sciencesGenetic driftGeneticsmedicineImmunogeneticsAnimalsHumansPOPULATION-STRUCTUREAdaptationeducationMolecular BiologyEcology Evolution Behavior and SystematicsDisease Reservoirs030304 developmental biologyTOLL-LIKE RECEPTORSHost-pathogen interactionPolymorphism Genetic[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]MX2 PROTEINGenetic DriftNECROSIS-FACTOR-ALPHADENSITY-FLUCTUATIONSmedicine.diseasebiology.organism_classificationEUROPEAN ROE DEERToll-Like Receptor 4030104 developmental biologyToll-Like Receptor 7Evolutionary biology3121 General medicine internal medicine and other clinical medicineVoleRODENT HOST[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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The genomic history of the Aegean palatial civilizations

2021

Summary The Cycladic, the Minoan, and the Helladic (Mycenaean) cultures define the Bronze Age (BA) of Greece. Urbanism, complex social structures, craft and agricultural specialization, and the earliest forms of writing characterize this iconic period. We sequenced six Early to Middle BA whole genomes, along with 11 mitochondrial genomes, sampled from the three BA cultures of the Aegean Sea. The Early BA (EBA) genomes are homogeneous and derive most of their ancestry from Neolithic Aegeans, contrary to earlier hypotheses that the Neolithic-EBA cultural transition was due to massive population turnover. EBA Aegeans were shaped by relatively small-scale migration from East of the Aegean, as e…

Bronze AgePopulation turnoverHuman MigrationAnatolia; Bronze Age; Cycladic civilization; Greece; Helladic civilization; Minoan civilization; Mycenean civilization; ancient DNA; paleogenomics; population geneticsSINGLE-NUCLEOTIDE POLYMORPHISMPopulation geneticsMinoan civilizationCivilizationBiologyAncient historyHIRISPLEX SYSTEMArticleGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicineBronze AgeSKIN COLOR PREDICTIONHumansAnatoliaPHYLOGENETIC ANALYSISBRONZE-AGEPOPULATION-STRUCTUREDNA AncientINDO-EUROPEAN LANGUAGESancient DNALACTASE-PERSISTENCE PHENOTYPEHistory AncientMinoan civilization030304 developmental biologySEQUENCE ALIGNMENTpopulation geneticCycladic civilization0303 health sciencesGreeceGenome Humanpopulation geneticsHelladic civilizationGenòmicapaleogenomicsAncient DNAHomogeneousGenome MitochondrialGreece AncientCivilitzacions palacials de l'EgeuMycenean civilizationLACTOSE DIGESTION030217 neurology & neurosurgeryGenètica
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Geographical and temporal structures of Legionella pneumophila sequence types in comunitat valenciana (Spain), 1998 to 2013

2015

ABSTRACT Legionella pneumophila is an accidental human pathogen associated with aerosol formation in water-related sources. High recombination rates make Legionella populations genetically diverse, and nearly 2,000 different sequence types (STs) have been described to date for this environmental pathogen. The spatial distribution of STs is extremely heterogeneous, with some variants being present worldwide and others being detected at only a local scale. Similarly, some STs have been associated with disease outbreaks, such as ST578 or ST23. Spain is among the European countries with the highest incidences of reported legionellosis cases, and specifically, Comunitat Valenciana (CV) is the se…

DNA BacterialBIOFILMS[SDV.BIO]Life Sciences [q-bio]/BiotechnologyGenotypeLegionellaOUTBREAKSequence HomologyZoologyRECOMBINATIONHuman pathogenLEGIONNAIRES-DISEASESOFTWAREBiologySpatial distributionApplied Microbiology and BiotechnologyLegionella pneumophilaLegionella pneumophilaMicrobiology03 medical and health sciencesSpatio-Temporal AnalysisEnvironmental MicrobiologyCluster AnalysisHumansTypingPOPULATION-STRUCTUREPhylogeny030304 developmental biology0303 health sciencesEcologyPublic and Environmental Health Microbiology030306 microbiologySTRAINSSCHEMELocal scaleGenetic VariationOutbreakSequence Analysis DNASequence typesbiology.organism_classification3. Good healthMolecular TypingLIFE[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologySpainLegionnaires' DiseaseFood ScienceBiotechnology
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Fossorial but widespread: the phylogeography of the common spadefoot toad (Pelobates fuscus), and the role of the Po Valley as a major source of gene…

2007

International audience; Pelobates fuscus is a fossorial amphibian that inhabits much of the European plain areas. To unveil traces of expansion and contraction events of the species' range, we sequenced 702 bp of the mitochondrial cytochrome b gene. To infer the population history we applied phylogeographical methods, such as nested clade phylogeographical analysis (NCPA), and used summary statistics to analyse population structure under a neutral model of evolution. Populations were assigned to different drainage systems and we tested hypotheses of explicit refugial models using information from analysis of molecular variance, nucleotide diversity, effective population size estimation, NCP…

0106 biological scienceshaplotypesPelobates fuscuspopulation-structuremismatch distribution01 natural sciencesNucleotide diversityCoalescent theorypostglacial range expansionEffective population sizePhylogeny[SDV.EE]Life Sciences [q-bio]/Ecology environment0303 health scienceseducation.field_of_studybiologyGeographyEcologyFossilssummarycoalescentCytochromes bEuropeMitochondrial-dnastatisticsAnuracladistic-analysisPopulationPelobates[SDV.BID]Life Sciences [q-bio]/Biodiversitynucleotide diversity010603 evolutionary biology03 medical and health sciencesstatistical phylogeographygeographical-distributionGeneticsVicarianceAnimalseducationEcology Evolution Behavior and Systematics030304 developmental biologyPopulation DensityinferenceDNA15. Life on landbiology.organism_classificationPhylogeographyspeciationEvolutionary biologyphylogeographical analysis[SDE.BE]Environmental Sciences/Biodiversity and EcologydivergencePelobates cultripesMolecular ecology
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Fragmentation-related patterns of genetic differentiation in pedunculate oak (Quercus robur) at two hierarchical scales

2016

Populations at species' range margins are expected to show lower genetic diversity than populations at the core of the range. Yet, long-lived, widespread tree species are expected to be resistant to genetic impoverishment, thus showing comparatively high genetic diversity within populations and low differentiation among populations. Here, we study the distribution of genetic variation in the pedunculate oak (Quercus robur L.) at its range margin in Finland at two hierarchical scales using 15 microsatellite loci. At a regional scale, we compared variation within versus among three oak populations. At a landscape scale, we examined genetic structuring within one of these populations, growing …

PETRAEA MATT. LIEBL.4112 ForestryMULTILOCUS GENOTYPE DATADIVERSITYMICROSATELLITESForestrygenetic diversitySD1-669.5mikrosatelliititFORESTL.COMMUNITYMARKERSmarginal populations1181 Ecology evolutionary biologyPOPULATION-STRUCTURECHLOROPLAST DNA VARIATIONFinland1183 Plant biology microbiology virology
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Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers

2023

Acknowledgements: The authors thank G. Marciani and O. Jöris for comments on archaeology; C. Jeong, M. Spyrou and K. Prüfer for comments on genetics; M. O’Reilly for graphical support for Fig. 5 and Extended Data Fig. 9; the entire IT and laboratory teams at the Department of Archaeogenetics of MPI-SHH for technical assistance; M. Meyer and S. Nagel for support with single-stranded library preparation; K. Post, P. van Es, J. Glimmerveen, M. Medendorp, M. Sier, S. Dikstra, M. Dikstra, R. van Eerden, D. Duineveld and A. Hoekman for providing access to human specimens from the North Sea (The Netherlands); M. D. Garralda and A. Estalrrich for providing access to human specimens from La Riera (S…

HistoryAncient dnaInteractionsCave/45/23AdmixtureSettore BIO/08 - Antropologia/631/208/457/631/181/276160 Other humanitiesContaminationHumansHuntingPalaeogenomicsPopulation-structureArchaeology ; Biological anthropology ; Evolutionary genetics ; Population geneticsHistory AncientHuman evolutionDiversityOccupationMultidisciplinary/45Genome HumanarticlePaleontologyLast glacial maximumHuman GeneticsGene PoolGenomics/631/181/19/2471PleistoceneEuropeGenomic transformationsArchaeology/631/181/2474AnthropologyHunter-gatherersGenome sequence
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Stable coexistence of genetically divergent Atlantic cod ecotypes at multiple spatial scales

2018

Abstract Coexistence in the same habitat of closely related yet genetically different populations is a phenomenon that challenges our understanding of local population structure and adaptation. Identifying the underlying mechanisms for such coexistence can yield new insight into adaptive evolution, diversification and the potential for organisms to adapt and persist in response to a changing environment. Recent studies have documented cryptic, sympatric populations of Atlantic cod (Gadus morhua) in coastal areas. We analysed genetic origin of 6,483 individual cod sampled annually over 14 years from 125 locations along the Norwegian Skagerrak coast and document stable coexistence of two gene…

0106 biological sciencesSympatryGENOMIC DIVERGENCECHROMOSOMAL REARRANGEMENTSBiodiversityecotypes010603 evolutionary biology01 natural sciencessympatry/dk/atira/pure/sustainabledevelopmentgoals/life_below_waterLOCAL ADAPTATIONGeneticsGadusPOPULATION-STRUCTURESDG 14 - Life Below Waterdispersaltemporal genetic stabilityGADUS-MORHUA L.MARINE FISHESEcology Evolution Behavior and SystematicsEcotypebiologyEcology010604 marine biology & hydrobiologynatural selectionGROWTH-RATEOriginal Articlesbiology.organism_classificationSTATIONARY ECOTYPESNATURAL-SELECTIONNORTH-SEAHabitatSympatric speciationAtlantic codconnectivityBiological dispersalOriginal ArticleGeneral Agricultural and Biological SciencesAtlantic cod
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Emergence and Phylodynamics of Citrus tristeza virus in Sicily, Italy

2013

Citrus tristeza virus (CTV) outbreaks were detected in Sicily island, Italy for the first time in 2002. To gain insight into the evolutionary forces driving the emergence and phylogeography of these CTV populations, we determined and analyzed the nucleotide sequences of the p20 gene from 108 CTV isolates collected from 2002 to 2009. Bayesian phylogenetic analysis revealed that mild and severe CTV isolates belonging to five different clades (lineages) were introduced in Sicily in 2002. Phylogeographic analysis showed that four lineages co-circulated in the main citrus growing area located in Eastern Sicily. However, only one lineage (composed of mild isolates) spread to distant areas of Sici…

Nonsynonymous substitutionCitrusGenetic-variationLineage (evolution)Population Dynamicslcsh:MedicinePopulation geneticsPlant Sciencelcsh:SciencePhylogenetic analysesPhylogenyGeneticsMultidisciplinarybiologyPhylogenetic treeGeographyCitrus tristeza virusAgriculturePhylogeneticsItalyRNA ViralEvolutionary dynamicsCross-protectionSequence AnalysisResearch ArticleClosterovirusDNA ComplementaryMolecular Sequence DataPlant PathogensCropsMicrobiologyViral EvolutionFruitsGenetic driftSpecies SpecificityVirologyMosaic-virusGenetic variationCTV Phylodynamics SicilyEvolutionary SystematicsPopulation-structureHost passageBiologyPlant DiseasesEvolutionary BiologyMaximum-likelihoodlcsh:RSettore AGR/12 - Patologia VegetaleComputational BiologyGenetic VariationBayes TheoremSequence Analysis DNAPlant Pathologybiology.organism_classificationAgronomyViral phylodynamicsDNA polymorphismEvolutionary biologyMolecular evolutionlcsh:Q
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