Search results for "POSITRON EMISSION TOMOGRAPHY"
showing 5 items of 235 documents
Transcranial Magnetic Stimulation and Neuroimaging Coregistration
2013
The development of neuroimaging techniques is one of the most impressive advancements in neuroscience. The main reason for the widespread use of these instruments lies in their capacity to provide an accurate description of neural activity during a cognitive process or during rest. This important advancement is related to the possibility to selectively detect changes of neuronal activity in space and time by means of different biological markers. Specifically, functional magnetic resonance imaging (fMRI), positron emission tomography (PET), single-photon emission computed tomography (SPECT), and nearinfrared spectroscopy (NIRS) use metabolic markers of ongoing neuronal activity to provide a…
Inter-crystal scatter in positron emission tomography: Identification techniques and effects on reconstructed images for AX-PET demonstrator
2012
La PET es una técnica de imagen en medicina nuclear que permite la visualización in-vivo y en 3D de procesos funcionales en seres vivos. Un escáner PET mide los rayos gamma producidos al aniquilarse un positrón, el cual es emitido por un radioisótopo inyectado al paciente. La eficiencia del sistema es una característica crucial de los escáneres PET de alta resolución dedicados a la imagen del cerebro o de animales pequeños con el fin de obtener una imagen más fiel o de reducir la actividad del radiotrazador, y por consiguiente, la dosis inyectada al paciente. El objetivo de este trabajo de investigación es mejorar la eficiencia y calidad de imagen de un prototipo de escáner PET axial (AX-PE…
Radiolabeling of Nanoparticles and Polymers for PET Imaging
2014
Nanomedicine has become an emerging field in imaging and therapy of malignancies. Nanodimensional drug delivery systems have already been used in the clinic, as carriers for sensitive chemotherapeutics or highly toxic substances. In addition, those nanodimensional structures are further able to carry and deliver radionuclides. In the development process, non-invasive imaging by means of positron emission tomography (PET) represents an ideal tool for investigations of pharmacological profiles and to find the optimal nanodimensional architecture of the aimed-at drug delivery system. Furthermore, in a personalized therapy approach, molecular imaging modalities are essential for patient screeni…
The Beginning and Development of the Theranostic Approach in Nuclear Medicine, as Exemplified by the Radionuclide Pair
2017
In the context of radiopharmacy and molecular imaging, the concept of theranostics entails a therapy-accompanying diagnosis with the aim of a patient-specific treatment. Using the adequate diagnostic radiopharmaceutical, the disease and the state of the disease are verified for an individual patient. The other way around, it verifies that the radiopharmaceutical in hand represents a target-specific and selective molecule: the “best one” for that individual patient. Transforming diagnostic imaging into quantitative dosimetric information, the optimum radioactivity (expressed in maximum radiation dose to the target tissue and tolerable dose to healthy organs) of the adequate radiotherapeutica…
Calf muscle activation strategies in healthy and injured achilles tendon conditions
2015
Artikkeliväitöskirja. Sisältää yhteenveto-osan ja neljä artikkelia. Article dissertation. Contains an introduction part and four articles.