Search results for "PPAR"

showing 10 items of 1686 documents

Increased airway inflammatory cells in endurance athletes: what do they mean?

2003

Inflammatory cells are increased in the airways of endurance athletes, but their role in causing exercise-induced respiratory symptoms and bronchoconstriction, or their possible long-term consequences, are uncertain.To put the results of athlete studies in perspective, by analysing the pathogenesis of airway cell changes and their impact on respiratory function.Athletes of different endurance sports at rest showed increased airway neutrophils. Elite swimmers and skiers also showed large increases in airway eosinophils and lymphocytes, possibly related to chronic, exercise-related exposure to irritants or cold and dry air, respectively. Post-exercise studies reported variable responses of ai…

NeutrophilsNeutrophilOsmolar ConcentrationRespiratory MucosaEosinophilLeukocyteSettore MED/10 - Malattie Dell'Apparato RespiratorioNitric OxideEosinophilsAsthma Exercise-InducedLeukocyte CountCell Adhesion MoleculeLeukocytesPhysical EnduranceHumansLymphocyteLymphocytesBronchial HyperreactivityCell Adhesion MoleculesHumanSports
researchProduct

Endurance exercise causes mild bronchial epithelial damage in humans

2009

Nonasthmatic runners halth-marathon induced sputum neutrophils bronchial epithelial cellsSettore MED/10 - Malattie Dell'Apparato RespiratorioSettore BIO/09 - Fisiologia
researchProduct

Novelties in COPD prognosis: Evolution of survival indexes

2015

Despite several techniques, such as non-invasive ventilation (NIV), have improved the outcome of the acute exacerbation, COPD remains affected by poor prognosis in the medium and long term. Moreover, the task of predicting prognosis remains a major challenge for respiratory physicians. In order to overcome this limitation, several indexes have been proposed to assess the COPD patient in his/her complexity. The rationale is that, by using numerical indexes physicians may improve their clinical judgment to tailor and share therapeutical choices, i.e. referring the patient for surgery or lung transplantation. On this ground, Almagro et al. recently proposed the CODEX index, as the latest evolu…

Noninvasive VentilationSurvivalPrognosiPrognostic indexesSettore MED/10 - Malattie Dell'Apparato RespiratorioPrognosismortalitySurvival RatePulmonary Disease Chronic ObstructivePrognostic indexeLung transplantationCOPD; Extracorporeal carbon dioxide removal; Lung surgery; Lung transplantation; Non-invasive ventilation (NIV); Prognosis; Prognostic indexes; SurvivalExtracorporeal carbon dioxide removalHumansCOPDNon-invasive ventilation (NIV)Lung surgery
researchProduct

Nonunion of the carpal navicular: surgical treatment and PRP

2013

Nonunion carpal navicularPRPSettore MED/33 - Malattie Apparato Locomotore
researchProduct

Search for gamma ray bursts with the ARGO-YBJ detector in scaler mode

2009

We report on the search for Gamma Ray Bursts (GRBs) in the energy range 1-100 GeV in coincidence with the prompt emission detected by satellites using the Astrophysical Radiation with Ground-based Observatory at YangBaJing (ARGO-YBJ) air shower detector. Thanks to its mountain location (Yangbajing, Tibet, P.R. China, 4300 m a.s.l.), active surface (about 6700 m**2 of Resistive Plate Chambers), and large field of view (about 2 sr, limited only by the atmospheric absorption), the ARGO-YBJ air shower detector is particularly suitable for the detection of unpredictable and short duration events such as GRBs. The search is carried out using the "single particle technique", i.e. counting all the …

Nuclear and High Energy PhysicsGamma ray burstAstrophysics::High Energy Astrophysical PhenomenaAir shower arrayAstrophysicsArgo-YbjSettore FIS/05 - Astronomia e AstrofisicaObservatoryGamma Rays ObservationsInstrumentationZenithArgoPhysicsRange (particle radiation)Apparati di sciameDetectorSettore FIS/01 - Fisica SperimentaleGamma rayGamma ray bursts Air shower arraysMode (statistics)Astrophysics::Instrumentation and Methods for AstrophysicsAstronomy and AstrophysicsRedshiftAir showerSpace and Planetary ScienceGamma Ray Bursts Gamma Ray EmissionAstrophysics - High Energy Astrophysical PhenomenaGamma-ray burst
researchProduct

Erratum to: Building bridges for innovation in ageing: Synergies between action groups of the EIP on AHA

2016

The authors would like to change and use the correct name of M. Khaitov which is M. Kaitov on this manuscript. The authors have incorrectly used her other name during the finalization of this research. With this, the authors hereby publish the correct author names as presented above. © 2016 Serdi and Springer-Verlag France

Nutrition and DieteticsNutrition & DieteticsGeriatrics gerontologybusiness.industryMedicine (miscellaneous)Settore MED/10 - Malattie Dell'Apparato RespiratorioallergyFinalizationAsthmaAction (philosophy)Correct nameMedicineEngineering ethicsGeriatrics and GerontologybusinessQuality of Life Research
researchProduct

Valutazione dello stato nutrizionale

2008

Nutrizione anzianiSettore MED/10 - Malattie Dell'Apparato Respiratorio
researchProduct

Economic impact of mepolizumab in uncontrolled severe eosinophilic asthma, in real life

2021

Abstract Background and aims Severe asthma is burdened by frequent exacerbations and use of oral corticosteroids (OCS) which worsen patients’ health and increase healthcare spending. Aim of this study was to assess the clinical and economic effect of adding mepolizumab (MEP) for the treatment of these patients. Methods Patients >18 years old, referred to 8 asthma clinics, starting MEP between May 2017 and December 2018, were enrolled and followed-up for 12 months. Information in the 12 months before mepolizumab were collected retrospectively. The evaluation parameters included: OCS use, number of exacerbations/hospitalizations, concomitant therapies, comorbidity, and annual number of workin…

OR Odds RatioPediatricsSevere asthmaExacerbationAnti IL-5; Comorbidities; Mepolizumab; OCS; Pharmacoeconomics; Severe asthmagastroesophageal reflux diseaseSettore MED/10 - MALATTIE DELL'APPARATO RESPIRATORIOICS inhaled corticosteroidRate ratioOCS Oral Corticosteroidslaw.inventionComorbiditiesLAMA long acting muscarinic antagonist0302 clinical medicineRandomized controlled trialfractional nitric oxideInterquartile rangelawlong acting beta 2 agonistOdds RatioImmunology and AllergyRR Rate Ratio030223 otorhinolaryngologyPharmacoeconomicLOS Length of stayLOSIQRLAMAMEP MepolizumabORCISD Standard DeviationMEPPharmacoeconomicsACT Asthma Control TestComorbiditieCI Confidence Intervalsmedicine.druglcsh:Immunologic diseases. AllergyPulmonary and Respiratory Medicinemedicine.medical_specialtyinterquartile rangelong acting muscarinic antagonistImmunologyLABALABA long acting beta 2 agonistComorbidities Mepolizumab OCS Pharmacoeconomics Severe asthma Anti IL-5RRArticleRate Ratiochronic obstructive pulmonary disease03 medical and health sciencesPharmacoeconomicsOCS Oral CorticosteroidAsthma Control TestConfidence IntervalsFeNO fractional nitric oxideRCTs Randomized Controlled TrialmedicineCOPDGERD gastroesophageal reflux diseaseFeNOIQR interquartile rangeMepolizumabSDAsthmaRCTsOral Corticosteroidsbusiness.industryGERDmedicine.diseaseICS inhaled corticosteroidsACTComorbidityRandomized Controlled TrialsCI Confidence IntervalRCTs Randomized Controlled TrialsOCSCOPD chronic obstructive pulmonary disease030228 respiratory systemICSStandard DeviationLength of stayAnti IL-5inhaled corticosteroidslcsh:RC581-607businessMepolizumab
researchProduct

RUOLO DELL’OSAS E DELL’OBESITA’ NELLA PATOGENESI DELLE ALTERAZIONI INFIAMMATORIE, FUNZIONALI, METABOLICHE E CARDIOVASCOLARI IN PAZIENTI OSAS E VALUTA…

OSAS NAFLDSettore MED/10 - Malattie Dell'Apparato Respiratorio
researchProduct

Renal Function In European Patients Studied For Suspected Sleep Apnea. The European Sleep Apnea Database (ESADA)

2013

OSASSettore MED/10 - Malattie Dell'Apparato Respiratorio
researchProduct