Search results for "PREM"

Premature diagnostic closure: An avoidable type of error

2013

A well-developed clinical interview makes it possible to adequately focus the diagnosis. However, cognitive psychology shows that mistakes are made when the persons face complex problems, such as those faced when making a diagnosis, especially if time or resources are limited. The main cause of failures in clinical reasoning is using "cognitive shortcuts". Among them, premature closure is a key factor triggering a diagnostic error. Cognitive errors are predictable and thus, it is possible to learn strategies to reduce or avoid them. Knowing the main features of cognitive shortcuts and identifying those automatically used is the first step towards preventing errors or minimizing their conseq…

Salsolinol and ethanol-derived excitation of dopamine mesolimbic neurons: new insights

2013

Evidence supporting the essential role of brain-derived ethanol metabolites in the excitation of dopamine (DA) midbrain neurons has multiplied in the last 10–15 years. The pioneer and influential behavioral studies by CM Aragon and colleagues (see Correa et al., 2012 for a complete review) and more recent data (Sanchez-Catalan et al., 2009; Marti-Prats et al., 2010, 2013) have repeatedly demonstrated the crucial role displayed by acetaldehyde (ACD) in the locomotor and other behavioral responses elicited by ethanol. Although these experiments mainly used an indirect measure (exploratory locomotion) as an index of the excitation of DA neurons in the ventral tegmental area (VTA), results stro…

2020

In this paper, we outline a theoretical account of the relationship between technology and human musicality. An enactive and biocultural position is adopted that assumes a close coevolutionary relationship between the two. From this position, we aim at clarifying how the present and emerging technologies, becoming embedded and embodied in our lifeworld, inevitably co-constitute and transform musical practices, skills, and ways of making sense of music. Therefore, as a premise of our scrutiny, we take it as a necessity to more deeply understand the ways that humans become affiliated to the ever-changing instruments of music technology, in order to better understand the coevolutionary impact …

Exposure to Gastric Acid Inhibitors Increases the Risk of Infection in Preterm Very Low Birth Weight Infants but Concomitant Administration of Lactof…

2018

Objective: To investigate whether exposure to inhibitors of gastric acidity, such as H2 blockers or proton pump inhibitors, can independently increase the risk of infections in very low birth weight (VLBW) preterm infants in the neonatal intensive care unit. Study design: This is a secondary analysis of prospectively collected data from a multicenter, randomized controlled trial of bovine lactoferrin (BLF) supplementation (with or without the probiotic Lactobacillus rhamnosus GG) vs placebo in prevention of late-onset sepsis (LOS) and necrotizing enterocolitis (NEC) in preterm infants. Inhibitors of gastric acidity were used at the recommended dosages/schedules based on the clinical judgmen…

On closures of discrete sets

2018

The depth of a topological space $X$ ($g(X)$) is defined as the supremum of the cardinalities of closures of discrete subsets of $X$. Solving a problem of Mart\'inez-Ruiz, Ram\'irez-P\'aramo and Romero-Morales, we prove that the cardinal inequality $|X| \leq g(X)^{L(X) \cdot F(X)}$ holds for every Hausdorff space $X$, where $L(X)$ is the Lindel\"of number of $X$ and $F(X)$ is the supremum of the cardinalities of the free sequences in $X$.

Packing dimensions of sections of sets

1999

We obtain a formula for the essential supremum of the packing dimensions of the sections of sets parallel to a given subspace. This depends on a variant of packing dimension defined in terms of local projections of sets.

Una mirada a los requisitos de la obtención de la nacionalidad española por residencia

2014

Vivimos en un mundo globalizado y la movilidad de las personas es identificativo de la modernidad, por esta razón la obtención de la nacionalidad española por residencia constituye un tema de importancia en el entorno social, económico, político y jurídico español. Para un extranjero adquirir la nacionalidad es un largo camino transitado más de espinas que de rosas, por ello este tema requiere ser visto con toda la seriedad que sea posible. El objetivo de este trabajo es reseñar algunas de las doctrinas de la jurisprudencia más actualizada en la materia, en relación a los requisitos exigidos para la obtención de la nacionalidad española. Partiendo de la premisa, que cuando un extranjero lle…

Étude exploratoire des obstacles à la transition universitaire selon le vécu d’étudiants français et belges

2020

International audience; Transition to Higher Education constitutes a challenging adjustment step for students that deserves major investigation. Yet, the transition obstacles are still overlooked. Most of international studies focused on individual predictors of adjustment and consider transition to Higher Education as a universal and invariant process. However, contextual characteristics of educational environment should be considered because they don’t imply the same requirements for adjustment. In order to address this limitation, this paper realized an exploratory comparison of first year student experience between a French and a Belgian university. The results highlighted similarities …

Progressive effect of beta amyloid peptides accumulation on CA1 pyramidal neurons: a model study suggesting possible treatments

2012

Several independent studies show that accumulation of β-amyloid (Aβ) peptides, one of the characteristic hallmark of Alzheimer's Disease (AD), can affect normal neuronal activity in different ways. However, in spite of intense experimental work to explain the possible underlying mechanisms of action, a comprehensive and congruent understanding is still lacking. Part of the problem might be the opposite ways in which Aβ have been experimentally found to affect the normal activity of a neuron; for example, making a neuron more excitable (by reducing the A- or DR-type K(+) currents) or less excitable (by reducing synaptic transmission and Na(+) current). The overall picture is therefore confus…

Filter Bank: a Directional Approach for Retinal Vessel Segmentation

2017

It is well known that retinal diseases are sometimes identified by tortuosity of the vessels, presence of exudates and hemorrhages while lesions of tissues are associated to diabetic retinopathy, retinopathy of prematurity and more general cerebrovascular problems. One of the main issues in this research field is detecting small curvilinear structures, thus the aim of this contribution is to introduce a non-supervised and automated methodology to detect features such as curvilinear structures in retinal images. The core of the proposed methodology consists in using an approach that resembles the “a trous” wavelet algorithm. With respect to the standard Gabor analysis our methodology is base…