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showing 10 items of 13045 documents

EMAS position statement: Predictors of premature and early natural menopause.

2019

Simoncini, Tommaso/0000-0002-2971-0079; Chung, Hsin-Fang/0000-0003-3261-5942; Mishra, Gita/0000-0001-9610-5904 WOS:000468709100014 PubMed ID: 31027683 Introduction: While the associations of genetic, reproductive and environmental factors with the timing of natural menopause have been extensively investigated, few epidemiological studies have specifically examined their association with premature (< 40 years) or early natural menopause (40-45 years). Aim: The aim of this position statement is to provide evidence on the predictors of premature and early natural menopause, as well as recommendations for the management of premature and early menopause and future research. Materials and methods…

medicine.medical_treatmentMenopause PrematureTwinsPremature ovarian insufficiencyOVARIAN DEVELOPMENT0302 clinical medicine3123 Gynaecology and paediatricsPregnancyRisk FactorsEpidemiology030212 general & internal medicineFamily historyAetiology030219 obstetrics & reproductive medicineObstetricsEstrogen Replacement TherapySmokingObstetrics and Gynecology3. Good healthEarly menopauseMenopauseParityMenarcheFemaleUnderweightmedicine.symptomMenopausemedicine.medical_specialtyPremature ovarian insufficiencyGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesAGEThinnessmedicineHumansPrematureMenarchePregnancyLIFE-COURSEbusiness.industryREPRODUCTIVE PERIODBody Weightmedicine.diseaseCOGNITIVE FUNCTIONBIRTH-WEIGHTAetiology; Early menopause; Premature ovarian insufficiency; Risk factors; Body Weight; Estrogen Replacement Therapy; Female; Humans; Menarche; Pregnancy; Risk Factors; Smoking; Thinness; Twins; Menopause; Menopause Premature; ParityBODY-MASS INDEXRisk factorsRISK-FACTORSHormone therapyCIGARETTE-SMOKINGbusinessSOCIOECONOMIC POSITIONMaturitas
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DNA fragmentation index, pAKT and pERK1/2 in cumulus cells are related to oocyte competence in patients undergoing in vitro fertilization programme

2019

SummaryActivated pERK1/2 and pAKT are key players in supporting cell survival and proliferation pathways. Translocation of pERK1/2 into the nucleus, where it interacts with transcription factors and DNA itself, is instrumental in exerting an anti-apoptotic effect. In this study, pAKT levels, pERK1/2 nuclear localization and DNA fragmentation index (DFI) in cumulus cells of single cumulus–oocyte complexes of patients undergoing in vitro fertilization programmes were evaluated and correlated with the clinical outcome of the related embryos. For a positive clinical outcome of blastocyst development, pERK1/2 nuclear localization and DFI value had a significant inverse relationship, whereas the …

medicine.medical_treatmentMolecular markerBiologyCell survivalIntracytoplasmic sperm injectionSettore MED/01 - Statistica MedicaAndrology03 medical and health sciences0302 clinical medicineOocyte qualitymedicineBlastocystViability assaySettore BIO/06 - Anatomia Comparata E Citologia030304 developmental biology0303 health sciences030219 obstetrics & reproductive medicineIn vitro fertilisationApoptosiCell BiologyOocytemedicine.anatomical_structureApoptosisDNA fragmentationDFIIntracellularDevelopmental BiologyZygote
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Spontaneous labour at term is associated with fetal monocyte activation.

1999

SUMMARYThe aetiology of both term and preterm labour remains incompletely understood. Maternal infectious diseases as well as intra-uterine infections were shown to be a well established cause of uncontrollable preterm delivery, indicating that inflammatory reactions, regulated by maternal immunecompetent cells, are implicated in labour-promoting mechanisms. To investigate the possibility that the activation of the fetal immune system may be involved in labour induction, we examined cytokine production patterns of different cord blood cell populations obtained from neonates after spontaneous onset of normal term labour and vaginal delivery (n = 25), vaginal delivery but induced term labour …

medicine.medical_treatmentT cellImmunologyInflammationGestational AgeBetamethasoneMonocytesMagnesium SulfateImmune systemFetusObstetric Labor PrematurePregnancymedicineImmunology and AllergyHumansLabor InducedLungreproductive and urinary physiologyFenoterolFetusLabor Obstetricbusiness.industryVaginal deliveryCesarean SectionInterleukin-6MonocyteInfant NewbornDelivery ObstetricFetal Bloodmedicine.anatomical_structureCytokineTocolytic AgentsCord bloodImmunologyFemaleOriginal Articlemedicine.symptombusinessClinical and experimental immunology
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K∗(892)0 and ϕ(1020) production in Pb-Pb collisions at √sNN =2.76 TeV

2015

The yields of the K∗(892)0 and ϕ(1020) resonances are measured in Pb-Pb collisions at √sNN=2.76 TeV through their hadronic decays using the ALICE detector. The measurements are performed in multiple centrality intervals at mid-rapidity (|y|<0.5) in the transverse-momentum ranges 0.3<pT<5 GeV/c for the K∗(892)0 and 0.5<pT<5 GeV/c for the ϕ(1020). The yields of K∗(892)0 are suppressed in central Pb-Pb collisions with respect to pp and peripheral Pb-Pb collisions (perhaps due to rescattering of its decay products in the hadronic medium), while the longer-lived ϕ(1020) meson is not suppressed. These particles are also used as probes to study the mechanisms of particle production. The shape of t…

meson productionPb-Pb collisionsNuclear Experiment
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Mappings of finite distortion between metric measure spaces

2015

We establish the basic analytic properties of mappings of finite distortion between proper Ahlfors regular metric measure spaces that support a ( 1 , 1 ) (1,1) -Poincaré inequality. As applications, we prove that under certain integrability assumption for the distortion function, the branch set of a mapping of finite distortion between generalized n n -manifolds of type A A has zero Hausdorff n n -measure.

metric measure spacesPure mathematicsInjective metric spaceta111Mathematical analysisMathematicsofComputing_GENERALProduct metricEquivalence of metricsConvex metric spaceIntrinsic metricDistortion (mathematics)mappings of finite distortionMetric (mathematics)Metric mapGeometry and TopologyMathematicsConformal Geometry and Dynamics of the American Mathematical Society
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Trade-offs among intensive forestry, ecosystem services and biodiversity in boreal forests

2018

Finnish forests are used extensively for timber production but are also providers of other ecosystem services and harbor unique biodiversity. The ecosystem services approach has so far been used marginally in the context of Finnish forestry; however, due to the multiple values associated with Finnish forests and the impacts forestry operations have on forest ecosystems, it is clearly applicable in this context. In this thesis, I studied the occurrence and severity of trade-offs among ecosystem services and biodiversity conservation in Finnish forests. I used forest inventory data, forest growth simulations, and multi-objective optimization to reveal how the severity of the trade-offs varies…

metsänkäsittelyforest managementsustainabilitykestävä metsätalousmonitavoiteoptimointibiodiversiteettimetsätaloustehometsätalousmetsiensuojelupuuntuotantoekosysteemipalvelutboreaalinen vyöhykeconflictsmulti-objective optimizationtimber productionsimulointiFinland
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Assessment of the production costs curve in micro-grids: a comparative analysis

2012

In micro-grids, due to their small scale, there is commonly only one power supplier. A competitive wholesale market hardly exists so the question about how to consider market issues for small producers within micro-grids arises. On the other hand, the specific features of micro-grids where load and generated power hardly find a balance, require that customers take part to regulation issues, maybe using demand response programs. In this paper, price responsive policies and its programs are discussed to answer this question. A case study of a micro-grid with one microturbine and two photovoltaic generators in Italy is analyzed to assess the overall production cost in order to build a price re…

micro-grid production costs price responsive demand response DSO time based program distributed generator electricity supply curveSettore ING-IND/33 - Sistemi Elettrici Per L'Energia
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Energy and economic assessment of a small domestic wind turbine in Palermo

2016

The cost effectiveness of micro-wind technology is closely linked to the annual energy production plants, which strongly depends on the wind characteristics and on the morphological properties of the installation site. The power curve of a wind turbine, supplied by manufacturers, characterizes the theoretical energy performance that it should have at a particular site. The behavior of a wind turbine in the field is affected by the speed but also by wind direction variations. At each change of direction and speed, the turbine will try to adapt to new conditions and the phase transition negatively influences the energy production. In order to experimentally confirm what above mentioned, the a…

micro-wind technologyEngineeringSettore ING-IND/11 - Fisica Tecnica AmbientaleWind powerPower stationMeteorologyRenewable Energy Sustainability and the Environmentbusiness.industryCost effectivenessWind hybrid power systemspower curve020209 energyEnergy Engineering and Power Technology02 engineering and technologyWind directionTurbineFERWind speedOffshore wind powerSettore ING-IND/10 - Fisica Tecnica Industriale0202 electrical engineering electronic engineering information engineeringwind energy productionElectrical and Electronic Engineeringbusiness2016 IEEE 16th International Conference on Environment and Electrical Engineering (EEEIC)
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Initial pH Conditions Shape the Microbial Community Structure of Sewage Sludge in Batch Fermentations for the Improvement of Volatile Fatty Acid Prod…

2022

Conversion of wastewater treatment plants into biorefineries is a sustainable alternative for obtaining valuable compounds, thus reducing pollutants and costs and protecting the environment and human health. Under specific operating conditions, microbial fermentative products of sewage sludge are volatile fatty acids (VFA) that can be precursors of polyhydroxyalkanoate thermoplastic polyesters. The role of various operating parameters in VFA production has yet to be elucidated. This study aimed to correlate the levels of VFA yields with prokaryotic microbiota structures of sewage sludge in two sets of batch fermentations with an initial pH of 8 and 10. The sewage sludge used to inoculate th…

microbiota structureMicrobiology (medical)pH influencesewage sludgeVirologyprokaryotic communityvolatile fatty acid production; sewage sludge; microbiota structure; pH influence; prokaryotic communityvolatile fatty acid productionMicrobiologyMicroorganisms; Volume 10; Issue 10; Pages: 2073
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Isolation and characterization of microsatellite markers in the liver fluke (Fasciola hepatica)

2004

PRIMER NOTE; International audience; Six microsatellite markers were isolated from Fasciola hepatica, a re-emerging parasite that causes important veterinary and public health problems. In a sample of 52 liver flukes from a region of hyperendemicity (Bolivian Altiplano), five microsatellite were polymorphic. Our results showed that liver flukes present important genetic variability, suggesting a preferential outcrossing reproduction mode for this hermaphroditic parasite.

microsatellitemedia_common.quotation_subjectOutcrossingBiochemistryGeneral Biochemistry Genetics and Molecular Biology030308 mycology & parasitology03 medical and health sciences[SDE.BE.PARA]Environmental Sciences/Biodiversity and Ecology/domain_sde.be.paraparasitic diseasesParasite hostingFasciola hepaticaGenetic variability030304 developmental biologymedia_commonGenetics0303 health sciencesliver flukeEcologybiologyFasciola hepaticaLiver flukebiology.organism_classificationIsolation (microbiology)3. Good healthMicrosatelliteReproductionMolecular Ecology Notes
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