Search results for "PRODUCT"

showing 10 items of 13045 documents

Induction of body weight loss through RNAi-knockdown of APOBEC1 gene expression in transgenic rabbits

2014

In the search of new strategies to fight against obesity, we targeted a gene pathway involved in energy uptake. We have thus investigated the APOB mRNA editing protein (APOBEC1) gene pathway that is involved in fat absorption in the intestine. The APOB gene encodes two proteins, APOB100 and APOB48, via the editing of a single nucleotide in the APOB mRNA by the APOBEC1 enzyme. The APOB48 protein is mandatory for the synthesis of chylomicrons by intestinal cells to transport dietary lipids and cholesterol. We produced transgenic rabbits expressing permanently and ubiquitously a small hairpin RNA targeting the rabbit APOBEC1 mRNA. These rabbits exhibited a moderately but significantly reduced …

perte de poidsobesityApolipoprotein BAgricultural BiotechnologyGene Expressionlcsh:MedicinetransgenesisSmall hairpin RNAAnimals Genetically Modified0302 clinical medicinesirnaRNA interferenceGene expressionGene Knockdown TechniquesBiologie de la reproductionMedicine and Health SciencesTransgenesIntestinal MucosaRNA Small Interferinglcsh:Science[SDV.BDD]Life Sciences [q-bio]/Development Biology2. Zero hunger0303 health sciencesGene knockdownReproductive BiologyMultidisciplinarybiologyGenetically Modified OrganismsBiologie du développementapobec1; obesity; editing apob; apob100; apob48; chylomicron; intestine; rabbit; sirna; transgenesis; knockdownchylomicronknockdownAgricultureInherited Metabolic DisordersDevelopment BiologyobésitéCholesterolPhenotypeTransgenic Engineering[ SDV.BDLR ] Life Sciences [q-bio]/Reproductive BiologyLiverapobapob48Gene Knockdown Techniquesanimal transgéniqueRNA Interferencelipids (amino acids peptides and proteins)RabbitsGenetic EngineeringResearch ArticleBiotechnologyexpression géniqueTransgeneAPOBEC-1 DeaminaseMolecular Sequence DatarabbitDiet High-Fat03 medical and health sciencesintestinCytidine DeaminaseWeight Loss[SDV.BDD] Life Sciences [q-bio]/Development BiologyAnimalsHumanslapinRNA Messenger[ SDV.BDD ] Life Sciences [q-bio]/Development BiologyintestineTriglycerides[SDV.BDLR] Life Sciences [q-bio]/Reproductive Biology030304 developmental biologyapobec1Base SequenceGenetically Modified AnimalsAPOBEC1editinglcsh:RBiology and Life Sciences[SDV.BDLR]Life Sciences [q-bio]/Reproductive BiologyMolecular biologyapob100DyslipidemiaMetabolic Disordersbiology.proteinlcsh:QRNA EditingApolipoprotein B-48030217 neurology & neurosurgery
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Exposition continue à des mélanges de perturbateurs endocriniens

2012

Dans ce projet, il est question d’explorer les effets de mélanges de perturbateurs endocriniens sur plusieurs générations, en considérant des cibles différentes (appareil reproducteur, glande mammaire, os, dent, tissu adipeux, glandes salivaires, cerveau...) et adaptées à chaque âge pour essayer de mieux comprendre comment agissent des perturbateurs endocriniens, en particulier ceux qui interfèrent avec les hormones sexuelles. Parmi les questions majeures que se pose le scientifique, figurent celles de l’effet d’une exposition prolongée à des mélanges de perturbateurs endocriniens depuis la conception jusqu’à l’âge adulte, et de la possibilité que ces expositions aient des répercussions sur…

perturbateur endocrinienreproduction[SDV] Life Sciences [q-bio]génistéinedose effetbisphénol A[SDV.EE.SANT] Life Sciences [q-bio]/Ecology environment/Healthmécanisme actioncellulefaible doseexposition
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Battery- and Petrol-Powered Chainsaws: An Investigation of Productivity in Conifer Thinning

2023

In recent years, battery technology has been greatly improved and some types of battery chainsaws are currently comparable with light-type petrol machines, suggesting their possible introduction into forest operations. In this context, the aim of this study was to test and compare the performance, in a Douglas-fir thinning, of two chainsaws similar in terms of weight and power, the Stihl MS 220 CB battery-powered saw and the Stihl MS 201 CM petrol-powered saw, measuring the working times and calculating the productivities. The results showed that, within a working day (about 6 h gross time), an average of 15 trees of 0.56 m3 was felled in each area. No statistically significant differences …

petrolbatteryForestryproductivity comparisonforest operationSettore AGR/06 - Tecnologia Del Legno E Utilizzazioni ForestalichainsawForests
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Model of hydrocarbons transport through the porous ground media

2014

Dispersion model of hydrocarbons transport in porous media has been presented. Mathematical description of this process allows to estimate whether the menace of ground waters can occur as a result of hydrocarbons transport through the soil. The convection term in the mass transport equation is taken into account due to the higher velocity of propagation in vertical direction. Additionally, introduction to the balance equation the biosorption link allows to take into account microorganisms influence on impurities concentration, especially on heavy oils derived compounds. To verify the theoretical model series of the experiment in the soil filter has been carried out.

petroleum derived products transport; hydrocarbons transport in soil; transport in porous media; the; soil filter method.Naukoêmni Tehnologìï
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Green Production of Aldehydes from Alcohols by Heterogeneous Photocatalysis

2010

photocatalysis TiO2 aldehydes alcohols green production
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Nucleon dissociation and incoherent J/ψ photoproduction on nuclei in ion ultraperipheral collisions at the CERN Large Hadron Collider

2019

Using the general notion of cross section fluctuations in hadron-nucleus scattering at high energies, we derive an expression for the cross section of incoherent J / ψ photoproduction on heavy nuclei d σ γ A → J / ψ Y / d t , which includes both elastic d σ γ p → J / ψ p / d t and proton-dissociation d σ γ p → J / ψ Y / d t photoproduction on target nucleons. We find that, with good accuracy, d σ γ A → J / ψ Y / d t can be expressed as a product of the sum of the d σ γ p → J / ψ p / d t and d σ γ p → J / ψ Y / d t cross sections, which have been measured at HERA, and the common nuclear shadowing factor, which is calculated using the leading twist nuclear shadowing model. Our prediction for …

photonuclear reactionsphoton lepton and quark productionQCD in nuclear reactionshiukkasfysiikkaydinfysiikkarelativistic heavy-ion collisions
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Photoperiodic regulation of life-history traits before and after eclosion: egg-to-adult development time, juvenile body weight and reproductive diapa…

2012

Photoperiod is the main environmental cue used by northern insects to predict the forthcoming seasonal changes and to adjust their life-history traits to fit these changes. We studied the effects of photoperiod on egg-to-adult development time, juvenile body mass and female reproductive diapause in two northern Drosophila montana populations with different patterns of voltinism. The most interesting findings were consistent between the populations: (1) when maintained before eclosion in short day conditions, representing early autumn, the flies developed faster and were lighter than when maintained in long day conditions, representing early summer, (2) photoperiodic time measurement is appa…

photoperiodismMaleendocrine systemLarvabiologyPhysiologyEcologyPeriod (gene)PhotoperiodReproductionVoltinismBody WeightOvaryDiapausebiology.organism_classificationLife history theoryInsect ScienceLarvaJuvenileAnimalsta1181DrosophilaFemaleDrosophilaJournal of Insect Physiology
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Northern Drosophila montana flies show variation both within and between cline populations in the critical day length evoking reproductive diapause

2013

Reproductive diapause, and its correct timing, plays an important role in the life cycle of many insect species living in a seasonally varying environment at high latitudes. In the present paper we have documented variation in the critical day length (CDL) for adult reproductive diapause and the steepness of photoperiodic response curves (PPRCs) in seven clinal populations of Drosophila montana in Finland between the latitudes 61 and 67°N, paying special attention to variation in these traits within and between cline populations. The isofemale lines representing these populations showed a sharp transition from 0% to 100% in females' diapause incidence in the shortening day lengths, indicate…

photoperiodismeducation.field_of_studyCalendar datePhysiologyEcologyPhotoperiodReproductionPopulationGenetic VariationCline (biology)DiapauseBiologyCold ClimateDiapause Insectbiology.organism_classificationInsect ScienceGenetic variationAnimalsta1181DrosophilaFemaleAdaptationeducationDrosophilaJournal of Insect Physiology
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Exclusive J=ψ Photoproduction off Protons in Ultraperipheral p-Pb Collisions at √sNN = 5.02 TeV

2014

photoproduction off protonsultra-peripheral p-Pb collisions
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Use of Biostimulants for Organic Apple Production: Effects on Tree Growth, Yield, and Fruit Quality at Harvest and During Storage

2018

The experiment was conducted during two consecutive seasons (years 2016 and 2017) in an organic apple orchard of the cultivar Jonathan. Several biostimulants were tested (10 in total), including humic acids, macro and micro seaweed extracts, alfalfa protein hydrolysate, amino acids alone or in combination with zinc, B-group vitamins, chitosan and a commercial product containing silicon. Treatments were performed at weekly intervals, starting from the end of May until mid-August. The macroseaweed extract was effective in stimulate tree growth potential in both years, as shown by a significantly larger leaf area (+20% as compared to control) and by an higher chlorophyll content and leaf photo…

photosynthesisorganic productionMalus × domesticaphysiological disordersfungiseaweed extractfood and beverageslcsh:SB1-1110Plant Sciencephenolic compoundslcsh:Plant cultureanthocyaninsOriginal ResearchFrontiers in Plant Science
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