Search results for "PRODUCTS"

showing 10 items of 980 documents

Sexual Quality of Life in Patients with Axial Spondyloarthritis in the Biologic Treatment Era.

2019

Author's accepted manuscript. This is a pre-copyediting, author-produced PDF of an article accepted for publication in The Journal of Rheumatology following peer review. The definitive publisher-authenticated version Berg, K. H., Rohde, G., Prøven, A., Benestad, E. E. P., Østensen, M. & Haugeberg, G. (2019). Sexual Quality of Life in Patients with Axial Spondyloarthritis in the Biologic Treatment Era. The Journal of Rheumatology, 46(9), 1075-1083 is available online at: https://www.jrheum.org/content/46/9/1075. Objective. To examine the relationship between demographics, disease-related variables, treatment, and sexual quality of life (SQOL) in men and women with axial spondyloarthritis (ax…

AdultMalemedicine.medical_specialtyMultivariate analysisSexual BehaviorImmunologyDiseasePersonal SatisfactionSeverity of Illness IndexBody Mass Index03 medical and health sciences0302 clinical medicineSex FactorsRheumatologyQuality of lifeInternal medicineSurveys and QuestionnairesSpondylarthritisImmunology and AllergyMedicineOutpatient clinicHumans030212 general & internal medicineAxial spondyloarthritisBASDAI030203 arthritis & rheumatologyBiological Productsbusiness.industryMiddle AgedRheumatologyVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Reumatologi: 759Antirheumatic AgentsQuality of LifeFemalebusinessBASFIThe Journal of rheumatology
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Increased proportion of comorbidities but no deterioration of sexual quality of life during a 5-year follow-up in patients with axial spondyloarthrit…

2021

Abstract Objective To explore patient perception of sexual quality of life (SQOL), an important category of QOL, in male and female patients with axial SpA (axSpA) after a 5 year follow-up. Methods A broad spectrum of demographic, disease-related, treatment and SQOL data was collected at baseline and at the 5 year follow-up. SQOL was assessed by the SQOL-Female (SQOL-F) questionnaire. For statistical analysis, McNemar’s tests, paired t-tests and multiple regression analyses were applied. Results A total of 245 axSpA patients (168 men and 77 women) from outpatient clinics were examined (mean age 46 years, mean disease duration 11.9 years at baseline). Compared with baseline, the patients had…

AdultMalemedicine.medical_specialtySexual BehaviorDiseaseComorbidityMcNemar's testRheumatologyQuality of lifeInternal medicineSurveys and QuestionnairesSpondylarthritismedicineOutpatient clinicHumansPharmacology (medical)Axial spondyloarthritisAnkylosing spondylitisBiological Productsbusiness.industryEnthesitisMiddle Agedmedicine.diseaseComorbidityAntirheumatic AgentsQuality of LifeFemalemedicine.symptombusinessFollow-Up StudiesRheumatology (Oxford, England)
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Postoperative Reduction of Fibrinolysis as a Prognostic Factor of Fatal Outcome

2001

For the resection of an esophagus carcinoma a mortality rate of 2 to 30% was described, It is still unclear whether an abdominothoracic or transhiatal intervention is superior regarding the outcome. To investigate the prognostic value of fibrinolytic markers, plasmin-α2-antiplasmin (PAP) and D-dimer (DD) values were determined daily in the early postoperative period for 11days. In addition, the course of PAP and DD concentrations was compared with the method of esophagectomy. Of the 28 patients enclosed in the study, 5 died between day 10 and day 34 owing to adult respiratory distress syndrome and septicemia. The PAP and DD concentrations increased in survivors after surgery until day 5 an…

AdultMalemedicine.medical_specialtyTime FactorsFatal outcomeEsophageal Neoplasmsmedicine.medical_treatmentReference range030204 cardiovascular system & hematologySensitivity and SpecificityGastroenterologyFibrin Fibrinogen Degradation Products03 medical and health sciences0302 clinical medicineInternal medicineFibrinolysisD-dimermedicineHumansFibrinolysinPostoperative PeriodSurvival rateAgedalpha-2-AntiplasminRespiratory distressbusiness.industryFibrinolysisMortality rateHematologyGeneral MedicineMiddle AgedPrognosisAntifibrinolytic AgentsSurgeryEsophagectomySurvival RateROC CurveEsophagectomyFemalebusinessBiomarkers030215 immunologyClinical and Applied Thrombosis/Hemostasis
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Adalimumab efficacy in enteropathic spondyloarthritis: A 12-mo observational multidisciplinary study

2017

AIM To report adalimumab (Ada) efficacy on articular-gastrointestinal disease and health-related quality of life (HRQoL) in patients with enteropathic spondyloarthritis (ES). METHODS A cohort of 52 patients with ES was evaluated in the departments of gastroenterology and internal medicine. At baseline, all patients underwent assessment by an integrated gastro-rheumatologic evaluation of articular and gastrointestinal activity, as well patient reported outcomes (PROs) of the HRQoL questionnaires. After this integrated evaluation and following a specific working flowchart, the Ada anti-tumor necrosis factor (TNF)-inhibitor was assigned to a cohort of 30 patients and its clinical efficacy was …

AdultMalemedicine.medical_specialtyTime FactorsTumor necrosis factor-inhibitorMultidisciplinary studyObservational StudyInflammatory bowel diseasesInflammatory bowel diseaseWorkflowEnteropathic spondyloarthriti03 medical and health sciences0302 clinical medicineCrohn DiseaseClinimetric assessmentInternal medicineSpondylarthritisTumor necrosis factor-inhibitorsAdalimumabHumansMedicinePatient Reported Outcome MeasuresPatient reported outcomes030203 arthritis & rheumatologyBiological ProductsTumor Necrosis Factor-alphabusiness.industryRemission InductionAdalimumabGastroenterologyInflammatory Bowel DiseasesGeneral MedicineMiddle AgedPatient reported outcomeEnteropathic spondyloarthritisClinimetric assessment; Enteropathic spondyloarthritis; Inflammatory bowel diseases; Multidisciplinary evaluation; Patient reported outcomes; Tumor necrosis factor-inhibitors; GastroenterologyTreatment OutcomeMultidisciplinary evaluationAntirheumatic AgentsCritical PathwaysQuality of LifeColitis UlcerativeFemale030211 gastroenterology & hepatologyObservational studybusinessmedicine.drug
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Dose-Adjusted Thrombosis Prophylaxis in Trauma Surgery According to Levels of D-Dimer

2000

In 234 trauma surgery patients, thrombosis prophylaxis with Nadroparin-Calcium low-molecular-weight heparin (LMWH) was adjusted according to levels of D-Dimer. Basic prophylaxis was 2,850 IU per day. If D-Dimer concentrations rose above 2 mg/L after the fourth postoperative (p.o.) day, LMWH was administered twice a day. Color Doppler ultrasound was performed between the fifth and seventh p.o. days. Patients were divided into a high-risk (group 1: hip, femur, or knee replacement surgery, n=102) and a moderate-risk group (group 2: other surgery of the knee, tibia, fibula, or foot, n=132). Group 1 showed significantly higher D-Dimer levels than group 2 (p0.001). Measurement of D-Dimer on days …

AdultMalemedicine.medical_specialtyTime Factorsmedicine.drug_classmedicine.medical_treatmentDeep veinAntithrombin IIIKnee replacementLow molecular weight heparinSensitivity and SpecificityFibrin Fibrinogen Degradation ProductsFractures BoneRisk FactorsAntifibrinolytic agentD-dimerHumansMedicineAgedAged 80 and overVenous Thrombosisbusiness.industryAnticoagulantNadroparinHematologyMiddle Agedmedicine.diseaseAntifibrinolytic AgentsSurgeryVenous thrombosismedicine.anatomical_structureAnesthesiaWounds and InjuriesFemalebusinessTrauma surgeryBiomarkersLeg InjuriesPeptide HydrolasesThrombosis Research
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Laboratory control of minimal heparinization during haemodialysis in patients with a risk of haemorrhage

1994

Abstract For patients undergoing dialysis with a high risk of haemorrhage there is no standardized procedure for anticoagulation during extracorporeal circulation. Minimal heparinization with a dose equivalent to half that used for chronic haemodialysis was employed in 49 patients (125 haemodialyses) performed after operative interventions (83.3%), after haemorrhagic events (5.2%) and after invasive investigations (11.5%). Using a biocompatible membrane and a low molecular weight heparin (bolus dose 500-1300 U; continuous infusion 100-400 U) it was possible to complete haemodialysis in 74 cases (Group 0) without clots appearing in the venous bubble trap of the tubing system. In 30 cases (Gr…

AdultMalemedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentAntithrombin IIILow molecular weight heparinHemorrhageFibrin Fibrinogen Degradation ProductsClinical ProtocolsRenal DialysisRisk FactorsmedicineHumansIn patientRisk factorDialysisAgedMonitoring PhysiologicDose-Response Relationship Drugbusiness.industryAnticoagulantExtracorporeal circulationHematologyGeneral MedicineHeparinHeparin Low-Molecular-WeightMiddle AgedAntifibrinolytic AgentsSurgeryFemaleHemodialysisbusinessPeptide Hydrolasesmedicine.drugBlood Coagulation & Fibrinolysis
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An up to 7-Year Retrospective Analysis of Biologic and Technical Complication With the All-on-4 Concept

2016

The aim of this study was to evaluate retrospectively biologic and technical complications as well as clinical and radiographic outcomes of patients treated with 4 implants according to the All-on-4 protocol and followed up to 7 years of function. Data from 56 consecutive patients presenting complete edentulous jaw, aged 18 years or older, treated between January 2008 and December 2013, were evaluated. The outcomes were implant and prosthetic survival and success rates, any complications, and marginal bone loss (MBL). Two-hundred twenty-four implants were placed in 56 patients. During the entire follow-up, 1 maxillary implant but no prosthesis failed during the healing process. Fourteen pat…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentRadiographyAlveolar Bone LossDentistryProspective data02 engineering and technologyProsthesis03 medical and health sciencesimplant complications0302 clinical medicinetilted implantsAll-on-4 complete edentulism dental implants complete-arch prosthesis tilted implants implant complicationsdental implantsRetrospective analysisHumansJaw EdentulousMedicineDental Restoration FailureProspective StudiesAgedRetrospective StudiesBiological ProductsAll-on-4business.industrycomplete-arch prosthesisSignificant differencecomplete edentulism030206 dentistryMiddle Aged021001 nanoscience & nanotechnologySurgeryTreatment OutcomeAll-on-4FemaleDental Prosthesis Implant-SupportedImplantOral Surgery0210 nano-technologybusinessComplicationFollow-Up StudiesJournal of Oral Implantology
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Polybrominated diphenyl ethers in foods from the Region of Valencia: Dietary exposure and risk assessment

2019

Abstract Dietary exposure to polybrominated diphenyl ethers (PBDEs) of the population in the Region of Valencia, Spain, was assessed. A group of 320 composite samples of different fatty foods was collected and analyzed, including the following: vegetable oils, and foods of animal origin such as (a) fish and seafood, (b) eggs, (c) milk and dairy products, and (d) meat and meat products. Two scenarios were assumed for left-censored results: lower-bound (LB) and upper-bound (UB). Vegetable oils, and fish and seafood presented the highest content of PBDEs [mean values of 503 and 464 pg g−1 wet weight (ww) for total PBDEs, respectively, in the UB]. The dominating congeners were BDE47 in the food…

AdultMeatEnvironmental EngineeringAdolescentEggsHealth Toxicology and MutagenesisFatty foodsPolybrominated Biphenyls0208 environmental biotechnologyPopulationFood ContaminationContext (language use)02 engineering and technology010501 environmental sciencesBiologyRisk Assessment01 natural sciencesAnimal originDietary ExposureYoung AdultPolybrominated diphenyl ethersHalogenated Diphenyl EthersAnimalsHumansEnvironmental ChemistryFood scienceChildeducation0105 earth and related environmental scienceseducation.field_of_studyDietary exposureFishesPublic Health Environmental and Occupational Healthfood and beveragesGeneral MedicineGeneral ChemistryPollutionDiet020801 environmental engineeringMeat ProductsMilkCongenerSpainEnvironmental PollutantsFemaleRisk assessmentChemosphere
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Detection of a new 3-base pair insertion mutation in the protease gene of human immunodeficiency virus type 1 during highly active antiretroviral the…

2005

To investigate a new insertion mutation in the protease (PR) gene of human immunodeficiency virus type 1 (HIV-1) in a patient extensively pretreated with antiretroviral drugs, genotypic analyses of plasma-derived viruses were performed by sequencing segments of 1302 nucleotides in the pol gene of HIV-1. Despite optimal compliance to highly active antiretroviral therapy (HAART) the patient showed poor virological success. Nucleotide sequences of retrospective available plasma samples exhibited a previously unknown 3-bp insertion mutation, corresponding to a leucine, between codons 31 and 32 of the PR gene. This kind of mutation appears to be very rare and it does not seem to be associated wi…

AdultSequence analysismedicine.medical_treatmentImmunologyMolecular Sequence DataGene Products polHIV InfectionsVirusHIV ProteaseVirologyAntiretroviral Therapy Highly ActivemedicineHumansInsertionCodonGeneBase PairingGeneticsProteasebiologyBase SequenceSequence Analysis DNAbiology.organism_classificationVirologyInfectious DiseasesLentivirusMutation (genetic algorithm)MutationHIV-1FemaleViral diseaseAIDS research and human retroviruses
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Dairy Consumption and Incidence of Breast Cancer in the 'Seguimiento Universidad de Navarra' (SUN) Project.

2021

Dairy products might influence breast cancer (BC) risk. However, evidence is inconsistent. We sought to examine the association between dairy product consumption—and their subtypes—and incident BC in a Mediterranean cohort. The SUN (“Seguimiento Universidad de Navarra”) Project is a Spanish dynamic ongoing cohort of university graduates. Dairy product consumption was estimated through a previously validated 136-item food frequency questionnaire (FFQ). Incident BC was reported in biennial follow-up questionnaires and confirmed with revision of medical records and consultation of the National Death Index. Hazard ratios (HR) and 95% confidence intervals (CI) were estimated with Cox regression …

Adultlcsh:TX341-641Breast NeoplasmsNational Death IndexDiet SurveysArticleMediterranean population03 medical and health sciences0302 clinical medicineBreast cancerbreast cancerRisk FactorsSurveys and QuestionnairesSUN cohortmedicineHumans030212 general & internal medicineLongitudinal StudiesProportional Hazards ModelsConsumption (economics)Nutrition and Dieteticsbusiness.industryProportional hazards modelIncidence (epidemiology)IncidenceHazard ratioMiddle Agedmedicine.diseaseConfidence intervalPostmenopausePremenopauseSpain030220 oncology & carcinogenesisCohortFemaleDairy Productsbusinesslcsh:Nutrition. Foods and food supplyFood ScienceDemographyNutrients
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