Search results for "PROGNOSIS"

showing 10 items of 2052 documents

Prognostic impact of systolic blood pressure in acute heart failure with preserved ejection fraction in older patients

2021

Abstract Aims Recent guidelines recommend a systolic blood pressure (SBP) target below 130 mmHg in heart failure patients with preserved ejection fraction (HFpEF), whatever their age. We investigated whether this intensive SBP control was associated with better survival in very old adults hospitalized for acute HFpEF. Methods and results We conducted an observational study in an acute geriatric unit: all consecutive patients discharged from hospital for acute heart failure from 1 March 2019 to 29 February 2020 with a diagnosis of HFpEF were included. Re‐hospitalization and all‐cause mortality at 1 year were compared according to the mean SBP at discharge (patients with a mean SBP < 130 mmHg…

medicine.medical_specialtyBlood PressureVentricular Function LeftElderlyInternal medicineRe‐hospitalizationDiseases of the circulatory (Cardiovascular) systemHumansMedicineMortalityMedical prescriptionProspective cohort studyAgedAged 80 and overHeart FailureEjection fractionbusiness.industryHazard ratioStroke VolumeOriginal ArticlesPreserved ejection fractionPrognosismedicine.diseaseConfidence intervalBlood pressureRC666-701Heart failureSystolic blood pressureCardiologyOriginal ArticleCardiology and Cardiovascular MedicinebusinessHeart failure with preserved ejection fractionESC Heart Failure
researchProduct

Materials and prognostic factors of bone regeneration in periapical surgery: a systematic review

2013

Objectives: Analyse the effectiveness of different materials and techniques used in guided tissue regeneration (GTR) applied in periapical surgery, comparing the success rate obtained in 4-wall defects and in through-and-through bone lesions as well as to establish prognostic factors. Material and Methods: A Cochrane, PubMed-MEDLINE and Scopus database search (October 2012 to March 2013) was conducted with the search terms “periapical surgery”, “surgical endodontic treatment”, “guided tissue regeneration”, “bone regeneration”, “bone grafts”, “barrier membranes” and “periapical lesions” individually and next, using the Boolean operator “AND”. The inclusion criteria were the use of GTR (bone …

medicine.medical_specialtyBone RegenerationMEDLINEDentistryOdontologíaReviewmedicineHumansBone regenerationProspective cohort studyGeneral Dentistrybusiness.industryPeriapical DiseasesRegeneration (biology)Retrospective cohort studyPrognosis:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludSurgerySearch termsOtorhinolaryngologyBone lesionUNESCO::CIENCIAS MÉDICASGuided Tissue Regeneration PeriodontalSurgeryOral SurgerybusinessPeriapical surgery
researchProduct

Head-to-head comparison of contemporary heart failure risk scores.

2021

Altres ajuts: acords transformatius de la UAB Aims: Several heart failure (HF) web-based risk scores are currently used in clinical practice. Currently, we lack head-to-head comparison of the accuracy of risk scores. This study aimed to assess correlation and mortality prediction performance of Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC-HF) risk score, which includes clinical variables + medications; Seattle Heart Failure Model (SHFM), which includes clinical variables + treatments + analytes; PARADIGM Risk of Events and Death in the Contemporary Treatment of Heart Failure (PREDICT-HF) and Barcelona Bio-Heart Failure (BCN-Bio-HF) risk calculator, which also include biomarke…

medicine.medical_specialtyCalibration (statistics)Head to headHeart failureSpearman's rank correlation coefficientRisk AssessmentCorrelationRisk FactorsInternal medicineNatriuretic Peptide BrainmedicineRisk modelsHumansOverall performanceMortalityNatriuretic PeptidesHeart FailureFramingham Risk Scorebusiness.industrymedicine.diseasePrognosisRisk predictionPeptide FragmentsClinical PracticeHeart failureCardiology and Cardiovascular MedicinebusinessBiomarkersEuropean journal of heart failureReferences
researchProduct

Comprehensive geriatric assessment is an essential tool to support treatment decisions in elderly patients with diffuse large B-cell lymphoma: A pros…

2015

We performed a multicenter study to validate the concept that a simple comprehensive geriatric assessment (CGA) can identify elderly, non-fit patients with diffuse large B-cell lymphoma (DLBCL) in whom curative treatment is not better then palliation, and to analyze potential benefits of treatment modulation after further subdividing the non-fit category by CGA criteria. One hundred and seventy-three patients aged &gt; 69 treated with curative or palliative intent by clinical judgement only were grouped according to CGA into fit (46%), unfit (16%) and frail (38%) categories. Two-year overall survival (OS) was significantly better in fit than in non-fit patients (84% vs. 47%; p &lt; 0.0001).…

medicine.medical_specialtyCancer ResearchMultivariate analysisLymphomaChemotherapeutic approaches; Immunotherapy; Lymphoma and Hodgkin disease; Hematology; Oncology; Cancer ResearchMEDLINEDisease-Free SurvivalInternal medicineComprehensive Assesment Diffuse large B cell lymphomaAntineoplastic Combined Chemotherapy Protocolsmedicine80 and overLarge B-CellHumansProspective StudiesProspective cohort studyGeriatric AssessmentAgedAged 80 and overChemotherapeutic approachesbusiness.industryPalliative CareGeriatric assessmentHematologymedicine.diseasePrognosisDiffuseSurgeryLymphomaSettore MED/15 - MALATTIE DEL SANGUETreatment OutcomeMulticenter studyOncologyLymphoma and Hodgkin diseaseMultivariate AnalysisTreatment decision makingImmunotherapyLymphoma Large B-Cell DiffusebusinessDiffuse large B-cell lymphoma
researchProduct

Reply to: Correspondence on "EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis - 2021 up…

2021

medicine.medical_specialtyCarcinoma HepatocellularHepatologybusiness.industryNon invasiveLiver NeoplasmsMEDLINEmedicine.diseasePrognosisSeverity of Illness IndexClinical PracticeLiver diseaseNAFLDmedicineHumansIntensive care medicinebusinessJournal of hepatology
researchProduct

Long-term observation of hepatocellular carcinoma recurrence after liver transplantation at a European transplantation centre

2019

BACKGROUND: The recurrence of hepatocellular carcinoma (HCC) is the strongest survival-limiting factor after liver transplantation (LT) in patients with HCC. In the face of donor organ shortage, it is necessary to identify factors associated with HCC recurrence in order to maximize the utility of the available grafts. OBJECTIVE: To study the phenomenon of HCC recurrence after LT at a European transplantation centre over the past 20 years. METHODS: Data from 304 HCC patients who underwent LT were prospectively recorded. Clinical and pathological factors were assessed for their association with recurrence. RESULTS: Fifty-one patients (16.8%) had HCC recurrence after LT. Patients exceeding the…

medicine.medical_specialtyCarcinoma Hepatocellularmedicine.medical_treatmentEconomic shortageLiver transplantationGastroenterology03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansIn patientneoplasmsProportional Hazards Modelsbusiness.industryLiver NeoplasmsGastroenterologyOriginal Articlesmedicine.diseasePrognosisdigestive system diseasesLiver TransplantationTransplantationEuropeTreatment OutcomeOncology030220 oncology & carcinogenesisHepatocellular carcinoma030211 gastroenterology & hepatologyNeoplasm Recurrence LocalbusinessLiver cancer
researchProduct

Caustic ingestion: development and validation of a prognostic score

2020

Abstract Background Caustic ingestion is a potentially severe condition and early identification of poor outcome is essential to improve management; however, prediction based on endoscopy alone can overestimate severity. This study aimed to develop and validate a prognostic score. Methods A prospective cohort study was designed to include all consecutive patients aged &gt; 15 years who presented with caustic ingestion between 1995 and 2017. Adverse outcome was defined by intensive care unit admission, urgent surgery, or death. The predictive value of clinical, analytical, and endoscopic variables was assessed in the first cohort (derivation cohort) and a prognostic score based on the result…

medicine.medical_specialtyCausticsLogistic regressionlaw.inventionEating03 medical and health sciences0302 clinical medicinelawPositive predicative valueInternal medicinemedicineHumansProspective Studies030212 general & internal medicineProspective cohort studyRetrospective Studiesbusiness.industryGastroenterologyRetrospective cohort studyOdds ratioPrognosisIntensive care unitConfidence intervalCohort030211 gastroenterology & hepatologybusinessEndoscopy
researchProduct

Non-Invasive Assessment of Liver Injury in Non-Alcoholic Fatty Liver Disease: A Review of Literature.

2016

NAFLD (Non-Alcoholic Fatty Liver Disease) is an increasingly significant public health issue, regarded as the most relevant liver disease of the twenty-first century. Approximately 20%-30% of NAFLD subjects develop a NASH (Non-Alcoholic Steato-Hepatitis), a condition which can potentially evolve to liver cirrhosis and hepatocellular carcinoma. For these reasons a proper evaluation of liver damage is a key point for diagnosis and prognosis and liver biopsy still remains the "gold standard" procedure both for discrimination between steatosis and steatohepatitis and assessment of the degree of liver fibrosis. Nonetheless, given it is an invasive, painful and costly procedure, a great research …

medicine.medical_specialtyCirrhosisFibrosiBiopsyClinical Decision-MakingApoptosis030204 cardiovascular system & hematologyBiochemistryGastroenterologyMultimodal Imaging03 medical and health sciencesLiver disease0302 clinical medicineNon-alcoholic Fatty Liver DiseaseInternal medicineMedicineAnimalsHumansMortalityMolecular BiologyLiver injurymedicine.diagnostic_testAnimalbusiness.industryFatty liverApoptosiBiomarkerGeneral Medicinemedicine.diseasePrognosisFibrosisdigestive system diseasesAlgorithmLiverLiver biopsyHepatocellular carcinomaMolecular Medicine030211 gastroenterology & hepatologySteatosisSteatohepatitisMorbiditybusinessAlgorithmsBiomarkersHumanCurrent molecular medicine
researchProduct

A new tool for sepsis screening in the Emergency Department

2021

Abstract Objectives In this study, we developed and evaluated the diagnostic accuracy of the Sepsis Index for early sepsis screening in the Emergency Department (ED). Methods Sepsis Index is based on the combination of monocyte distribution width (MDW) and mean monocyte volume (MMV). Sepsis Index≥1 was selected to define sepsis. We tested its diagnostic accuracy in an ED population stratified in four groups: controls, Systemic Inflammatory Response Syndrome (SIRS), infection, and sepsis, according to Sepsis-2 criteria. Results Patients with sepsis displayed higher median Sepsis Index value than patients without sepsis. At the receiver operating characterictis (ROC) curve analysis for the pr…

medicine.medical_specialtyClinical BiochemistryPopulationDiagnostic accuracyGastroenterologyMonocytesSepsisSepsisInternal medicineHumansMedicineeducationeducation.field_of_studybusiness.industryBiochemistry (medical)Curve analysisArea under the curvemonocyte distribution width (MDW)Emergency DepartmentGeneral MedicineEmergency departmentPrognosismedicine.diseaseSystemic inflammatory response syndromeROC CurveArea Under CurvebiomarkerBiomarker (medicine)mean monocyte volume (MMV)Emergency Service HospitalbusinessBiomarkersClinical Chemistry and Laboratory Medicine (CCLM)
researchProduct

Bladder augmentation and urinary diversion in patients with neurogenic bladder: Non-surgical considerations

2011

Segments from almost all parts of the bowel have been used for urinary diversion. As a result, the available absorptive surface area of the bowel is reduced, and the incorporation of bowel segments into the urinary tract may have metabolic consequences. This is an area somewhat neglected in the literature. Metabolic complications are rare, but sub-clinical metabolic disturbances are quite common. Several studies have demonstrated that some of the absorbent and secreting properties of the bowel tissue are preserved after incorporation into the urinary tract. Hyperchloraemic metabolic acidosis can occur if ileal and/or colon segments are used, as well as malabsorption of vitamin B(12) and bil…

medicine.medical_specialtyColonbusiness.industryPatient Selectionmedicine.medical_treatmentUrologyUrinary diversionUrologyVitamin B 12 DeficiencyUrinary DiversionPrognosislcsh:Diseases of the genitourinary system. Urologylcsh:RC870-923Bile Acids and SaltsPostoperative ComplicationsBladder augmentationIleumPediatrics Perinatology and Child HealthmedicineHumansIn patientUreterUrinary Bladder NeurogenicAcidosisbusinessJournal of Pediatric Urology
researchProduct