Search results for "PROGRESS"
showing 10 items of 1620 documents
Hematopoietic Stem Cell Transplantation in People With Active Secondary Progressive Multiple Sclerosis
2023
Background and ObjectivesUncontrolled evidence suggests that autologous hematopoietic stem cell transplantation (AHSCT) can be effective in people with active secondary progressive multiple sclerosis (SPMS). In this study, we compared the effect of AHSCT with that of other anti-inflammatory disease-modifying therapies (DMTs) on long-term disability worsening in active SPMS.MethodsWe collected data from the Italian Bone Marrow Transplantation Study Group and the Italian Multiple Sclerosis Register. Patients were considered eligible if treatment had been started after the diagnosis of SPMS. Disability worsening was assessed by the cumulative proportion of patients with a 6-month confirmed dis…
The impact of antiviral therapy on the course of chronic HCV infection: A systematic review
2003
Aim. Chronic hepatitis C is a progressive disease that leads to liver cirrhosis and hepatocellular carcinoma in a period ranging from 10 to 30 y. Many factors have been related to disease progression and, among them, persistent HCV replication has been advocated as one of the major determinant of hepatic deterioration. With this respect any treatment of chronic hepatitis C is mainly aimed to reduce necro-inflammation by suppressing viral activity in the long-term. We evaluated the persistence of HCV clearance after interferon therapy during follow-up in patients considered as long-term responders. Secondly, we analyzed the rate of progression from hepatitis to cirrhosis and hepatocellular c…
Assessing the impact of COVID-19 on liver cancer management (CERO-19)
2021
[Background & Aims] The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether the schedule of LC screening or procedures has been interrupted or delayed because of the COVID-19 pandemic.
p16INK4A (CDKN2A) gene deletion is a frequent genetic event in synovial sarcomas.
2006
We assessed the frequency of genomic deletion of p16 INK4A (CDKN2A) in synovial sarcomas (SSs) and its possible association with immunoexpression of p16 and cyclin D1 and the Ki-67 proliferation index using dualcolor fluorescence in situ hybridization (FISH) on tissue microarray sections of 41 histologically and molecularly confirmed SSs. A heterozygous p16 INK4A gene deletion was identified in 28 (74%) of 38 cases, with 25 (89%) of them showing abnormal p16 protein expression (20 negative and 5 heterogeneous). Of 25 cases, 19 (76%) exhibiting increased cyclin D1 expression also demonstrated heterozygous p16 INK4A deletion. No significant association was observed between p16 INK4A deletion …
An update on nuclear PDFs at the LHeC
2017
The prospects for a measurement of nuclear parton distribution functions (PDFs) at the Large Hadron--Electron Collider are discussed in the light of recent progress made in the front of global analysis of nuclear PDFs.
Validation of Neutrophil-to-lymphocyte Ratio in a Multi-institutional Cohort of Patients With T1G3 Non–muscle-invasive Bladder Cancer
2018
The aim of this multicenter study was to investigate the prognostic role of neutrophil-to-lymphocyte ratio (NLR) and to validate the NLR cutoff of 3 in a large multi-institutional cohort of patients with primary T1 HG/G3 non-muscle-invasive bladder cancer (NMIBC).
Identifying Problematic Study Progression and “At-Risk” Students in Higher Education in Finland
2018
Finland offers a specific example of a country with a broad enrolment in higher education, where the educational starting age is relatively high and where studies may last considerably longer than in most other European countries. This study attempted to identify at-risk students in Finnish universities with the greatest probability of non-completion of studies. This probability is by far the highest in the fields of information technology and information sciences and, in specific cases, in the fields of mathematics and science and economics and management. The situation of at-risk students is best described in terms of the scant use of time for present studies, uncertainty regarding their …
The Future We Want: a Learning Experience to Promote SDGs in Higher Education from the United Nations and University of Valencia
2021
This article shares the strategy for mainstreaming the Sustainable Development Goals (SDGs) at the University of Valencia (UV), which, although limited in its scale, may compel other Higher Education Institutions to think in technological and social progress aligned with the 2030 Agenda. It explicates a process driven by the UV, on the occasion of the 75th anniversary of the United Nations (UN), and in collaboration with the Service for Geospatial, Information, and Telecommunications Technologies from the UN Support Base in Valencia (Spain) to prepare the online event: “The United Nations We Want”. It was the culmination of a collaborative project between students and faculties from differe…
Henri Durel, Francis Bacon et l'affirmation d'une science nouvelle en Angleterre
2017
Comme l'indique le terme d'« affirmation » contenu dans le titre, cet ouvrage s'interesse a l'activite epistemologique plutot qu'a l'activite scientifique de Francis Bacon. Avec cette distinction en tete, Henri Durel cherche dans ce traite a rendre compte d'un paradoxe et a dissiper un malentendu. Le paradoxe reside dans le fait que Francis Bacon, reconnu d'abord par la Royal Society puis par la communaute scientifique au sens large comme « le pere de la science moderne », n'a jamais rien dec...
Anne Truelove e Baba the Turk: immagini del femminile in The Rake's Progress (1947-51) di Igor Stravinsky
2018
Il saggio ricostruisce la genesi di "The Rake's Progress" (La carriera di un libertino, 1947-51) di Igor Stravinsky, anche in relazione all'omonima serie di quadri e incisioni di William Hogarth e soffermandosi sulla contrapposizione rappresentativa e di linguaggio musicale che caratterizza i due personaggi femminili di Anne Truelove e Baba the Turk.