Search results for "PROM"
showing 10 items of 2286 documents
La sombra del botellón es alargada: nuevos retos en una sociedad de consumo
2002
La solución al problema del «botellón» no parece fácil, pues, más allá de que puede controlarse en la calle, la cuestión de fondo, el abuso de alcohol sigue presente en adolescentes y jóvenes. Este fenómeno social tiene raíces profundas que conviene ana¬lizar para poder ofertar respuestas que posibiliten evitar problemas a los jóvenes y a la sociedad. La sombra del botellón resulta alargada y oculta más cuestiones de lo que a simple vista parece, pues se entremezclan elementos económicos, culturales, políticos, educativos, sin que falten los existenciales.En este trabajo se analiza la situación de adolescentes y jóvenes en la sociedad actual, de forma especial en su relación con el alcohol …
Recomendaciones en el manejo de la pandemia por coronavirus SARS-CoV-2 (Covid-19) en pacientes con trasplante renal
2020
The SARS-CoV-2 (Covid-19) coronavirus pandemic is evolving very quickly and means a special risk for both immunosuppressed and comorbid patients. Knowledge about this growing infection is also increasing although many uncertainties remain, especially in the kidney transplant population. This manuscript presents a proposal for action with general and specific recommendations to protect and prevent infection in this vulnerable population such as kidney transplant recipients. Resumen: La pandemia por coronavirus SARS-CoV-2 (Covid-19) está evolucionando de manera muy rápida y representa un riesgo especial en pacientes inmunodeprimidos y con comorbilidades añadidas. El conocimiento sobre esta in…
Aspectos pragmático-lingüísticos del discurso del turismo de aventura: estudio de un caso: estudio de un caso
2014
El objetivo de este trabajo es ofrecer una visión general del discurso turístico con respecto a sus principales características pragmático-lingüísticas y contrastarlo con un subsegmento turístico concreto. En este caso, nos aproximaremos al turismo de aventura, un tipo de turismo que está creciendo exponencialmente en los últimos años y que, por tanto, está ganando importancia en el sector turístico en España. Para ello, analizaremos un corpus de textos promocionales sobre este tipo de turismo a fin de ejemplificar dichas características e ilustrar a los traductores profesionales acerca de las posibles dificultades que puedan encontrar durante la traducción de este tipo de textos al español…
El treball social davanta la crisis
2010
The economic crisis is a time when the social sector professional has to live up to expectations by informing, raising awareness, helping with self-organization and mobilisation from our privileged position as intermediaries with the people, honouring our ethical obligation to fight for the social rights of the underprivileged and defending them. One cannot understand a social worker still managing to remain faithful to their ethical principles while not participating in denunciation and campaigning groups and not having motives for getting involved in the denunciation protests and mobilizations taking place all over the land today.
Gestión del léxico turístico en páginas webs hoteleras de promoción: un ejemplo en alojamientos de la comunidad balear
2014
En este trabajo se muestran las nuevas posibilidades de gestión del léxico turístico a partir del análisis de páginas webs de promoción de alojamientos turísticos con la que se ha nutrido una base de datos. Se ilustrará la influencia decisiva del canal Internet en la promoción turística y las características con sello propio del nuevo discurso turístico generado en la web 2.0. Expertos en marketing y lingüistas se adaptan al cambio radical de paradigma y de género (cibergénero, macrogénero) con productos competitivos basados en la atribución continua de nuevos significados al léxico. Finalmente se presenta un modelo de trabajo con el corpus resultante de un grupo representativo de alojamien…
Il ruolo dell'adulto nei percorsi di apprendimento dei bambini.
2012
The Relationship Between Goal Orientation, Social Comparison Responses, Self-Efficacy, and Performance
2008
The present study examined whether social comparison responses (identification and contrast in social comparison) mediated the relationship between goal orientation (promotion and prevention) and self-efficacy, and whether self-efficacy was subsequently related with a better performance. As expected, the results showed that promotion-oriented individuals – who are focused on achieving success – had higher self-efficacy than prevention-oriented individuals – who are focused on avoiding failure. Only one of the social comparison responses had a mediating role. That is, the tendency to contrast oneself with others who were doing better mediated the relationship between a prevention goal orien…
In Vitro Evaluation of Enteric-Coated HPMC Capsules—Effect of Formulation Factors on Product Performance
2020
A comparative study on different enteric-coated hard capsules was performed. The influence of different formulation factors like choice of enteric polymer, triethyl citrate (TEC) concentration (plasticizer), talc concentrations (anti-tacking agent), and different coating process parameters on the sealing performance of the capsule and the disintegration time were investigated. Furthermore, the influence of different disintegration test methods (with disc vs. without disc and 50 mM U.S. Pharmacopoeia (USP) buffer pH 6.8 vs. biopredictive 15 mM phosphate buffer pH 6.5) was evaluated. All formulations showed sufficient but not equivalent acid resistance when tested. Polymer type was the main f…
Collateral sensitivity of drug-resistant ABCB5- and mutation-activated EGFR overexpressing cells towards resveratrol due to modulation of SIRT1 expre…
2019
Abstract Background In the drug discovery field, natural products deemed a precious source of novel lead compounds. They have the ability to bypass or overcome multidrug resistance (MDR) in cancer cells. Purpose In this study, the natural polyphenolic stilbene resveratrol (RES) has been studied for its cytotoxic activity toward MDR cancer cells. Methods Resazurin assay was used to investigate the cytotoxicity of RES not only against a panel of drug-resistant cancer cells overexpressing P-glycoprotein/ABCB1, BCRP/ABCG2, ABCB5 (ATP-binding cassette transporters), but also mutation-activated EGFR. The assessment of proteins expression was done by Western blot analysis. COMPARE and hierarchical…
CitA/CitB Two-Component System Regulating Citrate Fermentation in Escherichia coli and Its Relation to the DcuS/DcuR System In Vivo
2011
ABSTRACT Citrate fermentation by Escherichia coli requires the function of the citrate/succinate antiporter CitT ( citT gene) and of citrate lyase ( citCDEFXG genes). Earlier experiments suggested that the two-component system CitA/CitB, consisting of the membrane-bound sensor kinase CitA and the response regulator CitB, stimulates the expression of the genes in the presence of citrate, similarly to CitA/CitB of Klebsiella pneumoniae . In this study, the expression of a chromosomal citC-lacZ gene fusion was shown to depend on CitA/CitB and citrate. CitA/CitB is related to the DcuS/DcuR two-component system which induces the expression of genes for fumarate respiration in response to C 4 -di…