Search results for "PROPERTY"

Predicting Skin Permeability by Means of Computational Approaches: Reliability and Caveats in Pharmaceutical Studies

2019

The skin is the main barrier between the internal body environment and the external one. The characteristics of this barrier and its properties are able to modify and affect drug delivery and chemical toxicity parameters. Therefore, it is not surprising that permeability of many different compounds has been measured through several in vitro and in vivo techniques. Moreover, many different in silico approaches have been used to identify the correlation between the structure of the permeants and their permeability, to reproduce the skin behavior, and to predict the ability of specific chemicals to permeate this barrier. A significant number of issues, like interlaboratory variability, experim…

Star-free trace languages

1992

Abstract Generalizing a classical result of Schutzenberger to free partially commutative monoids, we prove that the family of star-free trace languages coincides with the family of aperiodic trace languages.

Tower sets and other configurations with the Cohen-Macaulay property

2014

Abstract Some well-known arithmetically Cohen–Macaulay configurations of linear varieties in P r as k-configurations, partial intersections and star configurations are generalized by introducing tower schemes. Tower schemes are reduced schemes that are a finite union of linear varieties whose support set is a suitable finite subset of Z + c called tower set. We prove that the tower schemes are arithmetically Cohen–Macaulay and we compute their Hilbert function in terms of their support. Afterwards, since even in codimension 2 not every arithmetically Cohen–Macaulay squarefree monomial ideal is the ideal of a tower scheme, we slightly extend this notion by defining generalized tower schemes …

Headquarters’ Control Capacity and the Choice of R&D Organizational Forms Abroad

2013

International audience; Recently, regarding globalization, the decentralization of R&D activities abroad by multinational companies (MNCs) has become important in developed countries. However, academic research has not given this topic sufficient attention. This paper explains how the efficiency of control and incentive mechanisms may affect the choice of organizational forms by MNCs that decentralize their R&D activities abroad. We identify five main organizational forms: wholly owned green-field subsidiary, wholly owned acquired subsidiary, joint venture, cross-licensing agreements, and unilateral licensing agreements. A questionnaire addressed to the R&D managers of American and European…

Single cigar-shaped nanopores functionalized with amphoteric amino acid chains: experimental and theoretical characterization.

2012

We present an experimental and theoretical characterization of single cigar-shaped nanopores with pH-responsive carboxylic acid and lysine chains functionalized on the pore surface. The nanopore characterization includes (i) optical images of the nanostructure obtained by FESEM; (ii) different chemical procedures for the nanopore preparation (etching time and functionalizations; pH and electrolyte concentration of the external solution) allowing externally tunable nanopore responses monitored by the current-voltage (I-V) curves; and (iii) transport simulations obtained with a multilayer nanopore model. We show that a single, approximately symmetric nanopore can be operated as a reconfigurab…

The dynamics of private property: between individual rights and common interests

2021

The present research explores the tension implicit in the right to property as an exclusionary right. The conceptualization of the right to property as a necessary component of individual freedom stands at odds with a universal exercise of the right in the context of scarcity. Both moral and economic considerations align in the necessity for property, but these justifications are of a principally divergent order. The natural law perspective is predominantly anchored in the atomic – the interest of the individual in personal freedom and well-being. The focal point of the economics approach is in the aggregate – the benefit to be reaped in the rights’ systematic application. The present work …

Multitasking associative networks.

2012

We introduce a bipartite, diluted and frustrated, network as a sparse restricted Boltzman machine and we show its thermodynamical equivalence to an associative working memory able to retrieve multiple patterns in parallel without falling into spurious states typical of classical neural networks. We focus on systems processing in parallel a finite (up to logarithmic growth in the volume) amount of patterns, mirroring the low-level storage of standard Amit-Gutfreund-Sompolinsky theory. Results obtained trough statistical mechanics, signal-to-noise technique and Monte Carlo simulations are overall in perfect agreement and carry interesting biological insights. Indeed, these associative network…

Large area strip edgeless detectors fabricated by plasma etching process

2007

This work presents the last results from large area edgeless detector, fabricated by Plasma Etching Process to reduce the conventional width of the terminating structure of position sensitive detectors to the detector rim.. A current terminating ring is used to decouple the electrical behavior of the surface from the sensitive volume within a few tens of micrometers. The detectors have been illuminated using an infrared laser and their surface scanned in order to understand their collection behavior at the cut edge. The detectors have very high efficiency up to the insensitive area which is located about 60 mum from the detector edge.

Characterization of greedy bases in Banach spaces

2017

Abstract We shall present a new characterization of greedy bases and 1-greedy bases in terms of certain functionals defined using distances to one dimensional subspaces generated by the basis. We also introduce a new property that unifies the notions of unconditionality and democracy and allows us to recover a better dependence on the constants.

2021

This study investigated the reasons that leaders have given for their leader role occupancy. By using a mixed-method approach and large leader data, we aimed to provide a more nuanced picture of how leader positions are occupied in real life. We examined how individual leadership motivation may associate with other reasons for leader role occupancy. In addition, we aimed to integrate the different reasons behind leader role occupancy into the framework of sustainable leader careers and its two indicators: leader’s health (occupational well-being) and performance (measured indirectly as followers’ occupational well-being). The survey data consisted of 1,031 leaders from various sectors of wo…