Search results for "PROs"

showing 10 items of 7271 documents

Differences in serum zinc levels in acutely ill and remitted adolescents and young adults with bulimia nervosa in comparison with healthy controls &a…

2017

Neuropsychiatric disease and treatment 2017(13), 2621-2630 (2017). doi:10.2147/NDT.S137549

050103 clinical psychologymedicine.medical_specialtyNeuropsychiatric Disease and Treatment610bulimia nervosaReference rangeeating disordersGastroenterology03 medical and health sciencesremission0302 clinical medicineInternal medicineMedicineserum concentrations0501 psychology and cognitive sciencesddc:610Young adultOriginal ResearchSerum zincbusiness.industryBulimia nervosazinc05 social sciencesSerum concentrationmedicine.disease030227 psychiatryEating disordersEndocrinologyAnorexia nervosa (differential diagnoses)Prospective researchbusinessNeuropsychiatric Disease and Treatment
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Chapter 12. Focus, prosody, and subject positions in L3 Spanish

2018

060201 languages & linguistics05 social sciencesSubject (philosophy)06 humanities and the arts050105 experimental psychologylanguage.human_languageLinguisticsFocus (linguistics)GermanEuropean PortuguesePolitical science0602 languages and literaturelanguage0501 psychology and cognitive sciencesProsody
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Chapter 6. Prosody, genres and evidentiality in Spanish

2018

060201 languages & linguisticsEvidentiality0602 languages and literature05 social sciences0501 psychology and cognitive sciences06 humanities and the artsSociologyProsody050105 experimental psychologyLinguistics
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Korpusonomastinen tutkimus slanginimistä Hesa ja Stadi digitaalisissa diskursseissa

2019

Artikkelissamme selvitämme Helsinkiä tarkoittavien slanginimien, Hesan ja Stadin, käyttöä uudentyyppisen aineiston ja menetelmän avulla. Aiemmissa näitä nimiä koskevissa tutkimuksissa lähtökohta on ollut kvalitatiivinen, mutta tässä tutkimuksessa lähdemme liikkeelle laajasta digitaalisesta aineistosta ja tilastollisista menetelmistä. Tutkimuksemme on uusi avaus nimistöntutkimuksessa, ja nimitämme sitä korpusavusteiseksi nimistöntutkimukseksi, lyhyemmin korpusonomastiikaksi.
 Aineistonamme on laaja Suomi24-keskustelufoorumista muodostettu ja Kielipankista saatava Suomi24-korpus, josta olemme hakeneet Hesa- ja Stadi-nimet. Tutkimus toteutetaan korpusavusteisena diskurssintutkimuksena. Mo…

060201 languages & linguisticspaikannimetkorpusavusteinen diskurssintutkimus (CADS)nimistöntutkimuskorpustutkimus0602 languages and literature6121 Kielitieteet06 humanities and the artsGeneral MedicineArtikkelitnimistöntutkimus paikannimet korpustutkimus diskurssiprosodia korpusavusteinen diskurssintutkimus (CADS)060202 literary studiesdiskurssiprosodia
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Case Management for Depression by Health Care Assistants in Small Primary Care Practices

2009

BACKGROUND: Case management by health care assistants in small primary care practices provides unclear benefit for improving depression symptoms. OBJECTIVE: To determine whether case management provided by health care assistants in small primary care practices is more effective than usual care in improving depression symptoms and process of care for patients with major depression. DESIGN: Cluster randomized, controlled trial. A central automated system generated the randomization scheme, which was stratified by urban and rural practices; allocation sequence was concealed until groups were assigned. SETTING: 74 small primary care practices in Germany from April 2005 to September 2007. PATIEN…

11035 Institute of General PracticeAdultMalemedicine.medical_specialtyAdolescentQuality Assurance Health CareAllied Health Personnel610 Medicine & healthMedication Adherencelaw.inventionInterviews as TopicYoung AdultQuality of life (healthcare)Ambulatory careRandomized controlled triallawGermanySurveys and QuestionnairesHealth careInternal MedicinemedicineHumansProspective StudiesCluster randomised controlled trialPsychiatryDepression (differential diagnoses)AgedAged 80 and overDepressive Disorderbusiness.industryPublic healthGeneral MedicineMiddle AgedAntidepressive AgentsTelephoneOutcome and Process Assessment Health Care2724 Internal MedicineFamily medicineManaged careFemaleFamily PracticebusinessCase ManagementAnnals of Internal Medicine
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Resistance to water and abrasion of a broad-spectrum sunscreen: a prospective, open-label study.

2015

1303 BiochemistryFrictionAbrasion (mechanical)Ultraviolet RaysDrug Evaluation PreclinicalSunburn610 Medicine & healthSunscreening AgentsDermatologyAdministration Cutaneous030226 pharmacology & pharmacyBiochemistry2708 Dermatology03 medical and health sciencesBroad spectrum0404 agricultural biotechnology0302 clinical medicineOpen label study1312 Molecular BiologymedicineHumansProspective StudiesSunburnComposite materialMolecular BiologySkin damageSkinWater resistanceChemistry10177 Dermatology ClinicWater04 agricultural and veterinary sciencesmedicine.disease040401 food scienceLiposomesHydrophobic and Hydrophilic InteractionsSunscreening AgentsExperimental dermatology
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Endogenous peroxynitrite modulates PGHS-1–dependent thromboxane A2 formation and aggregation in human platelets

2008

Aggregation of activated platelets is considerably mediated by the autocrine action of thromboxane A2 (TxA2) which is formed in a prostaglandin endoperoxide H2 synthase-1 (PGHS-1 or COX-1)-dependent manner. The activity of PGHS-1 can be stimulated by peroxides, an effect termed "peroxide tone", that renders PGHS-1 the key regulatory enzyme in the formation of TxA2. Activated platelets release nitric oxide (*NO) and superoxide (O*2) but their interactions with the prostanoid pathway have been controversially discussed in platelet physiology and pathophysiology. The current study demonstrates that endogenously formed peroxynitrite at nanomolar concentrations, originating from the interaction …

1303 BiochemistryPlatelet AggregationSuperoxideProstanoid610 Medicine & healthBiochemistryNitric oxideCell biologychemistry.chemical_compoundPeroxynitrous acidThromboxane A2Thromboxane A22737 Physiology (medical)BiochemistrychemistryPhysiology (medical)Peroxynitrous Acid10209 Clinic for CardiologyCyclooxygenase 1Humanslipids (amino acids peptides and proteins)PlateletPlatelet activationPeroxynitrite
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EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI): study protocol for a multicentre, observational trial

2021

Sağır, Özlem (Balikesir Author)

1682Epidemiologyurologic and male genital diseasesacute renal failureAdult Intensive & Critical CareAnaesthesiaCohort Studiessurgerychronic renal failureHumansMulticenter Studies as Topic1506Prospective Studiesadult intensive & critical careurogenital systemIncidenceGeneral MedicineAcute Kidney Injuryfemale genital diseases and pregnancy complicationscritical careRenal Replacement TherapyObservational Studies as Topicacute renal failure; adult intensive & critical care; chronic renal failure; epidemiology; surgeryAcute Renal FailureSurgeryepidemiologyadult intensive &ampChronic Renal Failure
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Effects of clopidogrel, prasugrel and ticagrelor on endothelial function, inflammatory and oxidative stress parameters and platelet function in patie…

2014

Introduction Particularly in the setting of acute coronary syndromes, the interplay between vascular and platelet function has been postulated to have direct clinical implications. The present trial is designed to test the effect of clopidogrel, prasugrel and ticagrelor on multiple parameters of vascular function, platelet aggregation, oxidative and inflammatory stress before and up to 4 weeks after coronary artery stenting. Methods and analysis The study is designed as a three-arm, parallel design, randomised, investigator-blinded study. Patients with unstable angina or non-ST elevation myocardial infarction undergoing coronary intervention with a drug-eluting stent will be randomised to r…

1683AdultBlood PlateletsMaleTicagrelorAdenosineTiclopidineAdolescent610 MedizinCardiovascular MedicineYoung AdultPercutaneous Coronary Intervention610 Medical sciencesProtocolHumansSingle-Blind Method1506Prospective StudiesAcute Coronary Syndrome1707AgedDrug-Eluting StentsMiddle AgedClopidogrelOxidative StressTreatment OutcomePurinergic P2Y Receptor AntagonistsFemaleEndothelium VascularPrasugrel HydrochloridePlatelet Aggregation InhibitorsFollow-Up Studies
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Irtolaisen elämänkulku : Ilmajoen työlaitoksen naiset 1962-1972

2015

Tutkimus käsittelee naisirtolaisten elämää sotienjälkeisessä Suomessa. Vuonna 1937 voimaan astuneessa laissa irtolaisuus määriteltiin tuomittavaksi elämäntavaksi ja sen nojalla yhteiskunnan kannalta vaikeat ongelmatapaukset voitiin määrätä työlaitokseen. Irtolaisnaiset tuomittiin työn vieroksunnan, juopottelun ja haureuden harjoittamisen perusteella. Työlaitos oli ankarin irtolaisuudesta määrätty rangaistus, johon turvauduttiin vasta sitten, kun lievemmät huoltotoimet osoittautuivat tehottomiksi. Tutkimuksessa käsitellään irtolaisuuden muodostumista Ilmajoen työlaitoksessa vuosien 1962-1972 välillä hoidettujen naisten elämäntarinoiden kautta. Tutkimuskohteena ei ole ainoastaan irtolaisuus v…

1960-lukunaisettyölaitoksetprostituutiorangaistuslaitoksetirtolaisuusirtolaishuoltoalkoholismi1960- ja 70-luvut1970-luku
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