Search results for "PTC"

showing 10 items of 122 documents

DHH is an independent prognosticator of oncologic outcome of clear cell renal cell carcinoma.

2014

Aberrant HH signaling has proved important in the pathogenesis of several solid cancers. Limited in vitro analyses suggested an oncogenic role for HH in renal cell carcinoma. In this explorative study we sought to validate aberrant HH expression in patients with renal cell carcinoma.A tissue microarray was constructed from 140 radical nephrectomy specimens of patients with clear cell renal cell carcinoma. We performed immunohistochemistry for Ki67 and HH pathway biomarkers, including PTCH1, Smo, SHH, IHH, DHH, Gli1, Gli2 and Gli3. Staining intensity was measured by automated image processing and related to tumor stage and grade. The impact of biomarker expression on cancer specific survival…

MalePathologymedicine.medical_specialtyUrologymedicine.medical_treatmentRenal cell carcinomamedicineCarcinomaHumansHedgehog ProteinsCarcinoma Renal CellDesert hedgehogAgedRetrospective StudiesKidneyTissue microarraybusiness.industryMiddle Agedmedicine.diseasePrognosisNephrectomyKidney NeoplasmsClear cell renal cell carcinomamedicine.anatomical_structurePTCH1Cancer researchFemalebusinessThe Journal of urology
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Immunohistochemistry Differentiates Papillary Thyroid Carcinoma Arising in Ectopic Thyroid Tissue from Secondary Lymph Node Metastases

2007

Objective: To verify whether immunohistochemistry might be useful in the distinction between a true laterocervical metastasis of an undetected thyroid carcinoma and a primary tumor outside the gland. Design: Galectin-3, cytokeratin 19, and HBME-1 were assessed in six cases (group A) of laterocervical masses harboring papillary thyroid carcinoma (PTC) but without a thyroid tumor, and in eight cases (group B) showing PTC both in the thyroid and in the laterocervical masses. In both groups, normal-looking follicles adjacent to the laterocervical neoplasia were present. Main outcome: We found that the apparently normal follicles in group A were negative for all the antibodies, while group B sho…

MaleThyroiditisPathologymedicine.medical_specialtyendocrine system diseasesEndocrinology Diabetes and MetabolismThyroid GlandHashimoto DiseaseChoristomaSettore MED/08 - Anatomia PatologicaMetastasisDiagnosis DifferentialThyroid carcinomaCytokeratinEndocrinologyHumansMedicineThyroid NeoplasmsLymph nodeAgedGoiterbusiness.industryThyroidMiddle Agedmedicine.diseasePrimary tumorCarcinoma Papillarymedicine.anatomical_structureLymphatic MetastasisimmunohistochemistryThyroidectomyImmunohistochemistryFemalepapillary thyroid carcinoma (PTC) ectopic thyroidbusinessImmunostainingThyroid
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Factors and Barriers of Implementing Early Warning, Support and Second Chance Support Systems for SMEs in the Baltic States

2021

COVID-19 creates insolvencies time bomb, even if economies are supported by the state. Following the liquidation or bankruptcy of a business, entrepreneurs in the EU mostly opt for a paid professional job rather than re-establishing their business [1]. Those entrepreneurs who re-establish their business after bankruptcy are experiencing faster growth than start-ups. The study points to significant current barriers and factors influencing the implementation of support, early warning and second chances in the Baltic States. There is a need to increase the competencies of both the businessmen and support providers on crisis management and the support already available in the broadest sense. By…

Market economyWarning systemState (polity)Coronavirus disease 2019 (COVID-19)Bankruptcymedia_common.quotation_subjectSupport systemBusinessCrisis managementThe BalticsBusiness environmentmedia_common
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Female directors, capital structure, and financial distress

2021

Abstract The composition of the board of directors is highly relevant to a firm’s capital structure and likelihood of financial distress. This study builds on the complementary proposals of agency theory and gender theories based on gender-differential behavior. We examine whether the gender diversity of the board affects firms’ capital structure (leverage, cost of debt, and debt maturity) and likelihood of bankruptcy. For a sample of European firms over the period 2002 to 2019, we find that the percentage of women directors is the most influential board characteristic in terms of capital structure decisions. This characteristic is negatively related to leverage, cost of debt, and debt matu…

MarketingLeverage (finance)Capital structureGender diversityBankruptcyCost of capitalCorporate governanceDebtmedia_common.quotation_subjectPrincipal–agent problemDemographic economicsBusinessmedia_commonJournal of Business Research
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La primera clase de créditos en el procedimiento concursal de reorganización judicial en Chile: ¿la gran ausente?

2017

The new Chilean bankruptcy law, No. 20,720 (D.O. of January 9, 2014), omitsexpressly referring to the credits of the first class in the judicial reorganizationprocedure of the debtor company. This omission has been understoodby a sector of the doctrine and even by the Superintendence of Insolvencyand Re-entrepreneurship as synonymous with the exclusion of said credits,which therefore would not be “reorganizable”. This work aims to raise and justify the opposite conclusion, with a view to overcomingone of the main obstacles that is currently facing this procedure, in its sphereof practical implementation and in view of its economic viability for the proponentdebtor. The research methods used…

ModalitiesWork (electrical)Bankruptcymedia_common.quotation_subjectPolitical scienceSubject (philosophy)DoctrineLegislationGeneral MedicineDebtorFirst classLaw and economicsmedia_commonCES Derecho
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CORPORATE BANKRUPTCY AND INSOLVENCY PREDICTION MODEL

2021

In any competitive economy, the risk of bankruptcy is pervasive. The research aims to contribute in improving the predictive power of bankruptcy and insolvency risk among companies by introducing new methods of processing and validation. This paper investigates the extensive application of the Z score model for predicting the economic-financial stability of Romanian companies in the manufacturing and extractive industries. A list of 37 financial indicators determined on the basis of the balance sheet data of 80 companies for the period 2015–2018 was used. Stepwise Least Squares Estimation through the Forward method allowed the identification of the most relevant ones. Canonical discriminant…

Multiple discriminant analysisInsolvencyHF5001-6182insolvencyComputer scienceStability (learning theory)Economic growth development planningmultiple discriminant analysisprediction modelbankruptcyDiscriminant function analysisBankruptcyHD72-88EconometricsPredictive powerBusinessBalance sheetRobustness (economics)FinanceriskTechnological and Economic Development of Economy
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"Table 85" of "Measurement of jet fragmentation in Pb+Pb and $pp$ collisions at $\sqrt{s_{NN}} = 5.02$ TeV with the ATLAS detector"

2020

Excess particles in jet in PbPb compared to pp collisions in different centrality selections for abs(jet rapidity) < 2.1.

PB PB --> JETS X5020.0PbPb) - D(pTpp)) * pTpTch = (D(pTpT < 4 GeVp p --> JETS Xjet fragmentation functions
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"Table 89" of "Measurement of jet fragmentation in Pb+Pb and $pp$ collisions at $\sqrt{s_{NN}} = 5.02$ TeV with the ATLAS detector"

2019

Excess particles in jet in PbPb compared to pp collisions in different centrality selections for abs(jet rapidity) < 2.1.

PB PB --> JETS X5020.0PbPb) - D(pTpp)) * pTpTch = (D(pTpT < 4 GeVp p --> JETS Xjet fragmentation functions
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PRIMARY PTCA: THE BEST CHOICE FOR ALL PATIENTS WITH ACUTE CORONARY SYNDROMES?

2006

PRIMARY PTCA: THE BEST CHOICE FOR ALL PATIENTS WITH ACUTE CORONARY SYNDROMES?

PRIMARY PTCA: THE BEST CHOICE FOR ALL PATIENTS WITH ACUTE CORONARY SYNDROMES?
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BRAFV600E mutation and timp-1 hyper-expression in classical variants of papillary thyroid carcinoma (PTC).

2009

PTC
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